CA2373291C - Acides carboxyliques de benzoquinolizine antibacteriens optiquement purs, procedes, compositions et procedes de traitement - Google Patents

Acides carboxyliques de benzoquinolizine antibacteriens optiquement purs, procedes, compositions et procedes de traitement Download PDF

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Publication number
CA2373291C
CA2373291C CA002373291A CA2373291A CA2373291C CA 2373291 C CA2373291 C CA 2373291C CA 002373291 A CA002373291 A CA 002373291A CA 2373291 A CA2373291 A CA 2373291A CA 2373291 C CA2373291 C CA 2373291C
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CA
Canada
Prior art keywords
benzo
methyl
fluoro
quinolizine
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002373291A
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English (en)
Other versions
CA2373291A1 (fr
Inventor
M.V. Patel
S.V. Gupte
Y. Chugh
D.G. Saoji
S.K. Agarwal
N.J. De Souza
H.F. Khorakiwala
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Wockhardt Ltd
Original Assignee
Wockhardt Ltd
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Filing date
Publication date
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Priority claimed from PCT/IN2000/000054 external-priority patent/WO2000068229A2/fr
Publication of CA2373291A1 publication Critical patent/CA2373291A1/fr
Application granted granted Critical
Publication of CA2373291C publication Critical patent/CA2373291C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

L'invention concerne des S-(-)- acides carboxyliques de benzoquinolizine optiquement purs de formule (I), y compris leurs sels pharmaceutiquement acceptables, dérivés, pseudopolymorphes et hydrates, sensiblement dépourvus de leurs R-(+)-isomères. L'invention concerne également des procédés relatifs à leur élaboration et des compositions pharmaceutiques renfermant un principe actif décrit dans l'invention. Les composés considérés ont une excellente activité antibactérienne. Les composés et les compositions en question peuvent être utilisés pour le traitement d'infections bactériennes locales et systémiques, de maladies et de troubles engendrés par des souches microbiennes sensibles et résistantes vis-à-vis des antibiotiques, sans risque concomitant d'effets préjudiciables associés au mélange racémique du principe actif décrit dans l'invention.
CA002373291A 1999-05-07 2000-05-08 Acides carboxyliques de benzoquinolizine antibacteriens optiquement purs, procedes, compositions et procedes de traitement Expired - Lifetime CA2373291C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
INPCT/IN99/00016 1999-05-07
IN9900016 1999-05-07
US17067699P 1999-12-14 1999-12-14
US60/170,676 1999-12-14
PCT/IN2000/000054 WO2000068229A2 (fr) 1999-05-07 2000-05-08 Acides carboxyliques de benzoquinolizine antibacteriens optiquement purs, procedes, compositions et procedes de traitement

Publications (2)

Publication Number Publication Date
CA2373291A1 CA2373291A1 (fr) 2000-11-16
CA2373291C true CA2373291C (fr) 2007-02-06

Family

ID=34519590

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002373291A Expired - Lifetime CA2373291C (fr) 1999-05-07 2000-05-08 Acides carboxyliques de benzoquinolizine antibacteriens optiquement purs, procedes, compositions et procedes de traitement

Country Status (2)

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AU (1) AU5425600A (fr)
CA (1) CA2373291C (fr)

Also Published As

Publication number Publication date
AU5425600A (en) 2000-11-21
CA2373291A1 (fr) 2000-11-16

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