CA2371592A1 - Composition pour la regeneration neuronale, comprenant des anticorps specifiques de la myeline et des complements - Google Patents

Composition pour la regeneration neuronale, comprenant des anticorps specifiques de la myeline et des complements Download PDF

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Publication number
CA2371592A1
CA2371592A1 CA002371592A CA2371592A CA2371592A1 CA 2371592 A1 CA2371592 A1 CA 2371592A1 CA 002371592 A CA002371592 A CA 002371592A CA 2371592 A CA2371592 A CA 2371592A CA 2371592 A1 CA2371592 A1 CA 2371592A1
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CA
Canada
Prior art keywords
complement
composition according
myelin
cells
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002371592A
Other languages
English (en)
Inventor
John D. Steeves
Jason K. Dyer
Hans S. Keirstead
Jason Bourque
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA002371592A priority Critical patent/CA2371592A1/fr
Priority claimed from PCT/CA2000/000440 external-priority patent/WO2000064473A1/fr
Publication of CA2371592A1 publication Critical patent/CA2371592A1/fr
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des nouvelles compositions ainsi que l'administration combinée de compléments sériques et d'anticorps fixant lesdits compléments. Les anticorps se lient spécifiquement à un ou plusieurs épitopes de myéline et aux compléments. Ces compositions sont utiles pour favoriser la repousse, la réparation et la régénération des neurones dans le système nerveux central d'un sujet mammifère. Les compositions et la méthode de l'invention peuvent être utilisés immédiatement après une lésion chronique.
CA002371592A 1999-04-28 2000-04-28 Composition pour la regeneration neuronale, comprenant des anticorps specifiques de la myeline et des complements Abandoned CA2371592A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002371592A CA2371592A1 (fr) 1999-04-28 2000-04-28 Composition pour la regeneration neuronale, comprenant des anticorps specifiques de la myeline et des complements

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CA2270364 1999-04-28
CA2,270,364 1999-04-28
PCT/CA2000/000440 WO2000064473A1 (fr) 1999-04-28 2000-04-28 Composition pour la regeneration neuronale, comprenant des anticorps specifiques de la myeline et des complements
CA002371592A CA2371592A1 (fr) 1999-04-28 2000-04-28 Composition pour la regeneration neuronale, comprenant des anticorps specifiques de la myeline et des complements

Publications (1)

Publication Number Publication Date
CA2371592A1 true CA2371592A1 (fr) 2000-11-02

Family

ID=25680912

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002371592A Abandoned CA2371592A1 (fr) 1999-04-28 2000-04-28 Composition pour la regeneration neuronale, comprenant des anticorps specifiques de la myeline et des complements

Country Status (1)

Country Link
CA (1) CA2371592A1 (fr)

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