CA2253078C - Composition immunologique et sa methode d'utilisation pour provoquer une demyelinisation transitoire dans le systeme nerveux central d'un mammifere afin de favoriser la regeneration des neurones - Google Patents

Composition immunologique et sa methode d'utilisation pour provoquer une demyelinisation transitoire dans le systeme nerveux central d'un mammifere afin de favoriser la regeneration des neurones Download PDF

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Publication number
CA2253078C
CA2253078C CA 2253078 CA2253078A CA2253078C CA 2253078 C CA2253078 C CA 2253078C CA 2253078 CA2253078 CA 2253078 CA 2253078 A CA2253078 A CA 2253078A CA 2253078 C CA2253078 C CA 2253078C
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CA
Canada
Prior art keywords
myelin
fragments
complement
antibodies
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA 2253078
Other languages
English (en)
Other versions
CA2253078A1 (fr
Inventor
John D. Steeves
Jason K. Dyer
Hans S. Keirstead
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
Original Assignee
University of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA 2219683 external-priority patent/CA2219683A1/fr
Application filed by University of British Columbia filed Critical University of British Columbia
Priority to CA 2253078 priority Critical patent/CA2253078C/fr
Publication of CA2253078A1 publication Critical patent/CA2253078A1/fr
Application granted granted Critical
Publication of CA2253078C publication Critical patent/CA2253078C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA 2253078 1997-10-28 1998-10-28 Composition immunologique et sa methode d'utilisation pour provoquer une demyelinisation transitoire dans le systeme nerveux central d'un mammifere afin de favoriser la regeneration des neurones Expired - Fee Related CA2253078C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA 2253078 CA2253078C (fr) 1997-10-28 1998-10-28 Composition immunologique et sa methode d'utilisation pour provoquer une demyelinisation transitoire dans le systeme nerveux central d'un mammifere afin de favoriser la regeneration des neurones

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CA2,219,683 1997-10-28
CA 2219683 CA2219683A1 (fr) 1997-10-28 1997-10-28 Composition immunologique et methodes d'utilisation pour perturber transitoirement la myelin au systeme nerveux central de mammiferes pour promouvoir la regeneration des neuronnes
CA2,251,410 1998-10-16
CA2251410 1998-10-16
CA 2253078 CA2253078C (fr) 1997-10-28 1998-10-28 Composition immunologique et sa methode d'utilisation pour provoquer une demyelinisation transitoire dans le systeme nerveux central d'un mammifere afin de favoriser la regeneration des neurones

Publications (2)

Publication Number Publication Date
CA2253078A1 CA2253078A1 (fr) 1999-04-28
CA2253078C true CA2253078C (fr) 2001-05-01

Family

ID=27170505

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2253078 Expired - Fee Related CA2253078C (fr) 1997-10-28 1998-10-28 Composition immunologique et sa methode d'utilisation pour provoquer une demyelinisation transitoire dans le systeme nerveux central d'un mammifere afin de favoriser la regeneration des neurones

Country Status (1)

Country Link
CA (1) CA2253078C (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10221390B2 (en) 2008-01-30 2019-03-05 Asterias Biotherapeutics, Inc. Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7285415B2 (en) 2002-07-11 2007-10-23 The Regents Of The University Of California Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
US20050101014A1 (en) 2002-07-11 2005-05-12 Keirstead Hans S. Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
KR20180084951A (ko) * 2015-11-20 2018-07-25 메모리얼 슬로안-케터링 캔서 센터 혈액 뇌척수액 장벽의 침투성을 조절하는 것

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10221390B2 (en) 2008-01-30 2019-03-05 Asterias Biotherapeutics, Inc. Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells

Also Published As

Publication number Publication date
CA2253078A1 (fr) 1999-04-28

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20131029