CA2365843A1 - Expression de l'alpha-fetoproteine humaine dans des cellules mammiferes - Google Patents

Expression de l'alpha-fetoproteine humaine dans des cellules mammiferes Download PDF

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Publication number
CA2365843A1
CA2365843A1 CA002365843A CA2365843A CA2365843A1 CA 2365843 A1 CA2365843 A1 CA 2365843A1 CA 002365843 A CA002365843 A CA 002365843A CA 2365843 A CA2365843 A CA 2365843A CA 2365843 A1 CA2365843 A1 CA 2365843A1
Authority
CA
Canada
Prior art keywords
rhuafp
mammalian cell
cell
nucleic acid
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002365843A
Other languages
English (en)
Inventor
Stace Lindsay
Robert Mulroy
Daniel Semeniuk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
ATLANTIC BIOPHARMACEUTICALS Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ATLANTIC BIOPHARMACEUTICALS Inc filed Critical ATLANTIC BIOPHARMACEUTICALS Inc
Publication of CA2365843A1 publication Critical patent/CA2365843A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4715—Pregnancy proteins, e.g. placenta proteins, alpha-feto-protein, pregnancy specific beta glycoprotein
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Biochemistry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne un acide nucléique, un vecteur, des cellules et des procédés d'expression de l'alpha-fétoprotéine humaine recombinée (rHuAFP), dans des cellules mammifères de culture.
CA002365843A 1999-03-09 2000-03-08 Expression de l'alpha-fetoproteine humaine dans des cellules mammiferes Abandoned CA2365843A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12366699P 1999-03-09 1999-03-09
US60/123,666 1999-03-09
PCT/US2000/006038 WO2000053759A1 (fr) 1999-03-09 2000-03-08 Expression de l'alpha-fetoproteine humaine dans des cellules mammiferes

Publications (1)

Publication Number Publication Date
CA2365843A1 true CA2365843A1 (fr) 2000-09-14

Family

ID=22410086

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002365843A Abandoned CA2365843A1 (fr) 1999-03-09 2000-03-08 Expression de l'alpha-fetoproteine humaine dans des cellules mammiferes

Country Status (6)

Country Link
EP (1) EP1161533A1 (fr)
JP (1) JP2002537838A (fr)
AU (1) AU3871200A (fr)
CA (1) CA2365843A1 (fr)
IL (1) IL145056A0 (fr)
WO (1) WO2000053759A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7208576B2 (en) * 1999-01-06 2007-04-24 Merrimack Pharmaceuticals, Inc. Non-glycosylated human alpha-fetoprotein, methods of production, and uses thereof
ATE418607T1 (de) * 1999-07-12 2009-01-15 Univ Bruxelles Genetisch modifiziertes nichthumanes tier mit mangel in alpha-fetoprotein
US7022892B1 (en) 1999-07-12 2006-04-04 Universite Libre De Bruxelles Non-human genetically modified mammal lacking the alpha-fetoprotein
EA011606B1 (ru) * 2004-07-14 2009-04-28 Эдуард Борисович Татулов Способы получения и применения рекомбинантного альфа-фетопротеина

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995029237A1 (fr) * 1994-04-25 1995-11-02 Genentech, Inc. Cardiotrophine et ses utilisations

Also Published As

Publication number Publication date
JP2002537838A (ja) 2002-11-12
WO2000053759A1 (fr) 2000-09-14
EP1161533A1 (fr) 2001-12-12
AU3871200A (en) 2000-09-28
WO2000053759A8 (fr) 2000-11-09
IL145056A0 (en) 2002-06-30

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Legal Events

Date Code Title Description
FZDE Discontinued