CA2362936A1 - Proteine kinase activee par la caspase - Google Patents

Proteine kinase activee par la caspase Download PDF

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Publication number
CA2362936A1
CA2362936A1 CA002362936A CA2362936A CA2362936A1 CA 2362936 A1 CA2362936 A1 CA 2362936A1 CA 002362936 A CA002362936 A CA 002362936A CA 2362936 A CA2362936 A CA 2362936A CA 2362936 A1 CA2362936 A1 CA 2362936A1
Authority
CA
Canada
Prior art keywords
smak
protein
cells
kinase
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002362936A
Other languages
English (en)
Inventor
Michael A. Rudnicki
Luc A. Sabourin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ottawa Health Research Institute
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2362936A1 publication Critical patent/CA2362936A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne une nouvelle protéine kinase appelée SMAK et apparentée à la famille de Ste20 ainsi que des méthodes de préparation et d'utilisation de cette protéine kinase. L'invention concerne également des acides nucléiques codant pour SMAK ainsi que des méthodes d'utilisation de ces acides nucléiques pour la préparation de SMAK et pour la préparation et l'identification d'analogues de SMAK.
CA002362936A 1999-02-19 2000-02-18 Proteine kinase activee par la caspase Abandoned CA2362936A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12078499P 1999-02-19 1999-02-19
US60/120,784 1999-02-19
PCT/CA2000/000165 WO2000049139A2 (fr) 1999-02-19 2000-02-18 Proteine kinase activee par la caspase

Publications (1)

Publication Number Publication Date
CA2362936A1 true CA2362936A1 (fr) 2000-08-24

Family

ID=22392543

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002362936A Abandoned CA2362936A1 (fr) 1999-02-19 2000-02-18 Proteine kinase activee par la caspase

Country Status (3)

Country Link
AU (1) AU2654900A (fr)
CA (1) CA2362936A1 (fr)
WO (1) WO2000049139A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007036053A1 (fr) * 2005-09-30 2007-04-05 Ottawa Health Research Institute Inhibiteurs de kinase de type ste20 (slk) et procedes de modulation de la progression du cycle cellulaire et de la motilite cellulaire

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997042212A1 (fr) * 1996-05-07 1997-11-13 The General Hospital Corporation Sok-1 et techniques d'utilisation
WO1999029857A1 (fr) * 1997-12-09 1999-06-17 The Children's Medical Center Corp. Deux nouvelles proteines de type kinase, les 'sterile 20' et leur mode d'utilisation
GB9726851D0 (en) * 1997-12-19 1998-02-18 Zeneca Ltd Human signal transduction serine/threonine kinase
DK1073723T3 (da) * 1998-04-14 2006-01-02 Sugen Inc STE20-relaterede proteinkinaser

Also Published As

Publication number Publication date
WO2000049139A3 (fr) 2001-01-25
WO2000049139A2 (fr) 2000-08-24
AU2654900A (en) 2000-09-04

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead