CA2362051C - Methods and compositions for use in perfusion applications - Google Patents
Methods and compositions for use in perfusion applications Download PDFInfo
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- CA2362051C CA2362051C CA2362051A CA2362051A CA2362051C CA 2362051 C CA2362051 C CA 2362051C CA 2362051 A CA2362051 A CA 2362051A CA 2362051 A CA2362051 A CA 2362051A CA 2362051 C CA2362051 C CA 2362051C
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Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/243,921 | 1999-02-03 | ||
| US09/243,921 US6589223B1 (en) | 1999-02-03 | 1999-02-03 | Method and compositions for use in perfusion applications |
| PCT/US2000/001703 WO2000045873A1 (en) | 1999-02-03 | 2000-01-24 | Methods and compositions for use in perfusion applications |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2362051A1 CA2362051A1 (en) | 2000-08-10 |
| CA2362051C true CA2362051C (en) | 2010-06-29 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2362051A Expired - Fee Related CA2362051C (en) | 1999-02-03 | 2000-01-24 | Methods and compositions for use in perfusion applications |
Country Status (14)
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| US (3) | US6589223B1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1150728A4 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2002536078A (cg-RX-API-DMAC7.html) |
| CN (1) | CN1200742C (cg-RX-API-DMAC7.html) |
| AR (1) | AR022482A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU765144B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR0008006A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2362051C (cg-RX-API-DMAC7.html) |
| EA (1) | EA003171B1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL144710A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA01007875A (cg-RX-API-DMAC7.html) |
| TW (1) | TW542728B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2000045873A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200107243B (cg-RX-API-DMAC7.html) |
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| US8409846B2 (en) | 1997-09-23 | 2013-04-02 | The United States Of America As Represented By The Department Of Veteran Affairs | Compositions, methods and devices for maintaining an organ |
| US6589223B1 (en) * | 1999-02-03 | 2003-07-08 | Biotime, Inc. | Method and compositions for use in perfusion applications |
| US6718735B2 (en) * | 2002-03-19 | 2004-04-13 | Baxter International Inc. | Albumin in a flexible polymeric container |
| US7354342B2 (en) * | 2003-07-30 | 2008-04-08 | Igt | Gaming device having a multiple coordinate award distributor including award percentages |
| US8304181B2 (en) | 2004-10-07 | 2012-11-06 | Transmedics, Inc. | Method for ex-vivo organ care and for using lactate as an indication of donor organ status |
| US9301519B2 (en) * | 2004-10-07 | 2016-04-05 | Transmedics, Inc. | Systems and methods for ex-vivo organ care |
| US12010987B2 (en) | 2004-10-07 | 2024-06-18 | Transmedics, Inc. | Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status |
| US8585380B2 (en) | 2004-10-07 | 2013-11-19 | Transmedics, Inc. | Systems and methods for ex-vivo organ care |
| US20100121273A1 (en) * | 2005-06-22 | 2010-05-13 | Kochanek Patrick M | Emergency preservation and resuscitation methods |
| US9078428B2 (en) | 2005-06-28 | 2015-07-14 | Transmedics, Inc. | Systems, methods, compositions and solutions for perfusing an organ |
| US7712094B2 (en) * | 2005-12-22 | 2010-05-04 | Alan Joshua Shapiro | Method and apparatus for replicating a panoplex onto a storage medium from a master |
| DK1942726T3 (en) * | 2006-04-19 | 2017-04-10 | Transmedics Inc | METHODS FOR EX VIVO ORGANIC CARE |
| US9457179B2 (en) | 2007-03-20 | 2016-10-04 | Transmedics, Inc. | Systems for monitoring and applying electrical currents in an organ perfusion system |
| KR101183965B1 (ko) * | 2007-10-05 | 2012-09-18 | 후소 야쿠힝 고교 가부시끼가이샤 | 안정한 탄산수소 이온 함유 약액 |
| US20090123436A1 (en) * | 2007-11-08 | 2009-05-14 | Surmodics, Inc. | Cryopreservative compositions and methods |
| US9247728B2 (en) | 2008-01-31 | 2016-02-02 | Transmedics, Inc. | Systems and methods for ex vivo lung care |
| SE534527C2 (sv) * | 2009-09-24 | 2011-09-20 | Vivoline Medical Ab | Förfarande, anordning och vätska för behandling av ett hjärta efter uttagning |
| DK4032401T3 (da) | 2011-04-14 | 2025-12-15 | Transmedics Inc | Fremgangsmåde til fremstilling af en organplejeopløsning til maskinperfusion ex-vivo af donorlunger |
| US8579880B2 (en) * | 2012-03-01 | 2013-11-12 | Outcome Solutions, Llc | Devices and methods for making and administering an intravenous liquid with supersaturated dissolved gas |
| IL303658B2 (en) | 2014-06-02 | 2024-07-01 | Transmedics Inc | Ex vivo organ care system |
| DK3229588T3 (da) | 2014-12-12 | 2025-06-23 | Transmedics Inc | Anordning og fremgangsmåde til organperfusion |
| DK3347084T3 (da) | 2015-09-09 | 2021-02-15 | Transmedics Inc | Aortakanyle til ex vivo-organplejesystem |
| DK3462861T5 (da) | 2016-05-30 | 2024-01-08 | Transmedics Inc | Fremgangsmåde til ex vivo-lungeventilati on med et varierende udvendigt tryk |
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| US3677024A (en) | 1970-01-20 | 1972-07-18 | Paul E Segall | Preservation and storage of biologic materials |
| US3937821A (en) | 1971-08-21 | 1976-02-10 | Kyorin Seiyaku Kabushiki Kaisha | Plasma substitute including artificial starch and method for the preparation thereof |
| US4001401A (en) | 1975-02-02 | 1977-01-04 | Alza Corporation | Blood substitute and blood plasma expander comprising polyhemoglobin |
| US4061736A (en) | 1975-02-02 | 1977-12-06 | Alza Corporation | Pharmaceutically acceptable intramolecularly cross-linked, stromal-free hemoglobin |
| DE2801123C2 (de) | 1977-01-26 | 1986-01-02 | Armour Pharma GmbH & Co KG, 3440 Eschwege | Verfahren zur Herstellung eines intravenös applizierbaren Serumeiweiß-Präparates |
| EP0185759B2 (en) | 1984-06-22 | 2004-06-02 | Btg International Limited | Electrolyte solutions and (in vivo) use thereof |
| US5084377A (en) | 1984-09-19 | 1992-01-28 | Larry Rowan | Cryogenic suspension method |
| US4908350A (en) | 1985-10-31 | 1990-03-13 | The Regents Of The University Of California | Hyperosmotic/hyperoncotic solutions for resuscitation of hypodynamic shock |
| US5210083A (en) | 1986-07-17 | 1993-05-11 | Ed. Geistlich Sohne A.G. Fur Chemische Industrie | Pharmaceutical compositions |
| JPS6360931A (ja) | 1986-08-29 | 1988-03-17 | Noboru Sato | 血液または血液製剤保存液およびこれを用いた血液または血液製剤の保存方法 |
| US4927806A (en) | 1987-04-23 | 1990-05-22 | The Regents Of The University Of California | Saturated salt/concentrated dextran formulation to treat hemorrhage |
| WO1989005659A1 (en) | 1987-12-24 | 1989-06-29 | Borody Thomas J | Orthostatic lavage solutions |
| US5130230A (en) * | 1988-05-02 | 1992-07-14 | Cryomedical Sciences, Inc. | Blood substitute |
| US4923442A (en) * | 1988-05-02 | 1990-05-08 | Cryomedical Sciences Inc. | Blood substitute |
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| CA2066374C (en) | 1991-04-19 | 2002-01-29 | Paul E. Segall | Solution for perfusing primates |
| EP0663821A4 (en) | 1991-08-08 | 1997-09-17 | Leigh D Segel | BLOOD SUBSTITUTE WITH FLUOROCARBON. |
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| CN1102851C (zh) * | 1993-06-04 | 2003-03-12 | 生物时间公司 | 类血浆溶液 |
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| US6589223B1 (en) * | 1999-02-03 | 2003-07-08 | Biotime, Inc. | Method and compositions for use in perfusion applications |
-
1999
- 1999-02-03 US US09/243,921 patent/US6589223B1/en not_active Expired - Lifetime
-
2000
- 2000-01-24 AU AU33497/00A patent/AU765144B2/en not_active Ceased
- 2000-01-24 WO PCT/US2000/001703 patent/WO2000045873A1/en not_active Ceased
- 2000-01-24 EP EP00911630A patent/EP1150728A4/en not_active Withdrawn
- 2000-01-24 CA CA2362051A patent/CA2362051C/en not_active Expired - Fee Related
- 2000-01-24 BR BR0008006-3A patent/BR0008006A/pt not_active Application Discontinuation
- 2000-01-24 JP JP2000596992A patent/JP2002536078A/ja active Pending
- 2000-01-24 IL IL14471000A patent/IL144710A0/xx not_active IP Right Cessation
- 2000-01-24 EA EA200100855A patent/EA003171B1/ru not_active IP Right Cessation
- 2000-01-24 CN CNB008060290A patent/CN1200742C/zh not_active Expired - Fee Related
- 2000-01-24 MX MXPA01007875A patent/MXPA01007875A/es not_active Application Discontinuation
- 2000-02-02 AR ARP000100449A patent/AR022482A1/es not_active Application Discontinuation
- 2000-02-03 TW TW089102018A patent/TW542728B/zh not_active IP Right Cessation
-
2001
- 2001-08-31 ZA ZA200107243A patent/ZA200107243B/en unknown
-
2003
- 2003-05-23 US US10/445,392 patent/US6991624B2/en not_active Expired - Lifetime
-
2005
- 2005-10-12 US US11/249,757 patent/US7503913B2/en not_active Expired - Fee Related
-
2009
- 2009-06-02 JP JP2009133059A patent/JP5180912B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1200742C (zh) | 2005-05-11 |
| CA2362051A1 (en) | 2000-08-10 |
| AU3349700A (en) | 2000-08-25 |
| EP1150728A4 (en) | 2004-09-29 |
| EA200100855A1 (ru) | 2002-02-28 |
| JP2002536078A (ja) | 2002-10-29 |
| BR0008006A (pt) | 2001-12-04 |
| MXPA01007875A (es) | 2002-08-20 |
| JP5180912B2 (ja) | 2013-04-10 |
| TW542728B (en) | 2003-07-21 |
| US7503913B2 (en) | 2009-03-17 |
| JP2009242404A (ja) | 2009-10-22 |
| AU765144B2 (en) | 2003-09-11 |
| AR022482A1 (es) | 2002-09-04 |
| IL144710A0 (en) | 2002-06-30 |
| CN1346286A (zh) | 2002-04-24 |
| EA003171B1 (ru) | 2003-02-27 |
| US20040018966A1 (en) | 2004-01-29 |
| US6589223B1 (en) | 2003-07-08 |
| ZA200107243B (en) | 2002-09-02 |
| US20060088606A1 (en) | 2006-04-27 |
| WO2000045873A1 (en) | 2000-08-10 |
| EP1150728A1 (en) | 2001-11-07 |
| US6991624B2 (en) | 2006-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20200124 |