CA2360366A1 - Use of 3-isoxazolidinones and hydroxylamine acids for the treatment of infections - Google Patents

Use of 3-isoxazolidinones and hydroxylamine acids for the treatment of infections Download PDF

Info

Publication number
CA2360366A1
CA2360366A1 CA002360366A CA2360366A CA2360366A1 CA 2360366 A1 CA2360366 A1 CA 2360366A1 CA 002360366 A CA002360366 A CA 002360366A CA 2360366 A CA2360366 A CA 2360366A CA 2360366 A1 CA2360366 A1 CA 2360366A1
Authority
CA
Canada
Prior art keywords
methyl
dimethyl
chlorophenyl
chloro
isoxazolidinone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002360366A
Other languages
English (en)
French (fr)
Inventor
Hassan Jomaa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jomaa Pharmaka GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19903666A external-priority patent/DE19903666A1/de
Application filed by Individual filed Critical Individual
Publication of CA2360366A1 publication Critical patent/CA2360366A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002360366A 1999-01-13 2000-01-12 Use of 3-isoxazolidinones and hydroxylamine acids for the treatment of infections Abandoned CA2360366A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19900907 1999-01-13
DE19900907.4 1999-01-13
DE19903666.7 1999-01-30
DE19903666A DE19903666A1 (de) 1999-01-13 1999-01-30 Arzneimittel mit einem Gehalt an 3-Isoxazolidinonen und Hydroxylaminsäuren als Wirkstoff und ihre Verwendung
PCT/EP2000/000165 WO2000041473A2 (de) 1999-01-13 2000-01-12 Verwendung von 3-isoxazolidinonen und hydroxylaminsäuren zur behandlung von infektionen

Publications (1)

Publication Number Publication Date
CA2360366A1 true CA2360366A1 (en) 2000-07-20

Family

ID=26051290

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002360366A Abandoned CA2360366A1 (en) 1999-01-13 2000-01-12 Use of 3-isoxazolidinones and hydroxylamine acids for the treatment of infections

Country Status (14)

Country Link
EP (1) EP1143941A3 (xx)
JP (1) JP2002534440A (xx)
CN (1) CN1342078A (xx)
AU (1) AU2436600A (xx)
BR (1) BR0007491A (xx)
CA (1) CA2360366A1 (xx)
CZ (1) CZ20012380A3 (xx)
HU (1) HUP0105412A2 (xx)
IL (1) IL143795A0 (xx)
NO (1) NO20013464L (xx)
PL (1) PL350128A1 (xx)
SK (1) SK9502001A3 (xx)
TR (1) TR200102019T2 (xx)
WO (1) WO2000041473A2 (xx)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023247301A1 (en) * 2022-06-22 2023-12-28 Syngenta Crop Protection Ag Herbicidal compounds

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1443930A1 (en) 2001-10-25 2004-08-11 AstraZeneca AB Isoxazoline derivatives useful as antimicrobials

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL45174A (en) * 1973-08-10 1976-12-31 Merck & Co Inc Antibacterial preparations containing a compound of the type 3-fluoro-D-alanine and a cyclocarrin compound that is converted in the nitrogen atom
US3911007A (en) * 1974-08-08 1975-10-07 Searle & Co N-substituted N-benzyloxy-2-methyl-2-(4-halophenoxy)propionamides
FR2290442A1 (fr) * 1974-11-06 1976-06-04 Aries Robert Nouvelles rifamycines
EP0219923B1 (en) * 1985-04-30 1992-09-02 Takeda Chemical Industries, Ltd. Antibiotic derivatives, their production and use
GB8531838D0 (en) * 1985-12-30 1986-02-05 Wellcome Found Aryl derivatives
JPS63119476A (ja) * 1986-11-05 1988-05-24 Takeda Chem Ind Ltd イソキサゾリドン誘導体
JPS63119462A (ja) * 1986-11-05 1988-05-24 Takeda Chem Ind Ltd 五員環ｎ−スルホ化合物
US5288896A (en) * 1992-01-15 1994-02-22 Warner-Lambert Company 3,5-di-t-butyl-4-hydroxylphenylmethylhydroxylamines and their derivatives, pharmaceutical compositions, and methods of use therefor
EP0689538B1 (en) * 1993-03-16 1998-08-12 British Biotech Pharmaceuticals Limited Hydroxamic acid derivatives as metalloproteinase inhibitors
EP0715619A4 (en) * 1993-08-23 1997-03-19 Immunex Corp INHIBITORS OF TNF-ALPHA SECRETION
GB9401129D0 (en) * 1994-01-21 1994-03-16 British Bio Technology Hydroxamic acid derivatives as metalloproteinase inhibitors
WO1996013263A2 (en) * 1994-11-01 1996-05-09 Research Corporation Technologies, Inc. Methods of treatment of viral disease with inhibitors of sphingolipid biosynthesis
US5919790A (en) * 1996-10-11 1999-07-06 Warner-Lambert Company Hydroxamate inhibitors of interleukin-1β converting enzyme
US6251913B1 (en) * 1997-03-28 2001-06-26 Zeneca Limited Hydroxamic acids substituted by heterocycles useful for inhibition of tumor necrosis factor
AUPO721997A0 (en) * 1997-06-06 1997-07-03 Queensland Institute Of Medical Research, The Anticancer compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023247301A1 (en) * 2022-06-22 2023-12-28 Syngenta Crop Protection Ag Herbicidal compounds

Also Published As

Publication number Publication date
AU2436600A (en) 2000-08-01
WO2000041473A2 (de) 2000-07-20
IL143795A0 (en) 2002-04-21
PL350128A1 (en) 2002-11-04
CN1342078A (zh) 2002-03-27
JP2002534440A (ja) 2002-10-15
EP1143941A3 (de) 2002-02-06
SK9502001A3 (en) 2002-05-09
TR200102019T2 (tr) 2002-04-22
BR0007491A (pt) 2001-11-20
EP1143941A2 (de) 2001-10-17
NO20013464D0 (no) 2001-07-12
WO2000041473A3 (de) 2001-11-29
NO20013464L (no) 2001-09-12
HUP0105412A2 (hu) 2002-05-29
CZ20012380A3 (cs) 2002-01-16

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued