CA2354612A1 - Homologue recepteur du facteur de necrose tumorale (trh1) - Google Patents

Homologue recepteur du facteur de necrose tumorale (trh1) Download PDF

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Publication number
CA2354612A1
CA2354612A1 CA002354612A CA2354612A CA2354612A1 CA 2354612 A1 CA2354612 A1 CA 2354612A1 CA 002354612 A CA002354612 A CA 002354612A CA 2354612 A CA2354612 A CA 2354612A CA 2354612 A1 CA2354612 A1 CA 2354612A1
Authority
CA
Canada
Prior art keywords
necrosis factor
tumor necrosis
factor receptor
receptor homologue
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002354612A
Other languages
English (en)
Inventor
Michael A. Bowen
Nathan Siemers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2354612A1 publication Critical patent/CA2354612A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Transplantation (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention concerne l'identification du nouvel homologue récepteur du facteur de nécrose tumorale (TRH1), de même que ses séquences d'acide nucléique et d'acide aminé qui l'identifie. Cette invention concerne aussi des techniques d'utilisation de ces séquences d'acide nucléique, de la protéine TRH1, d'un anticorps monoclonal spécifique au récepteur du facteur de nécrose tumorale, d'un ligand du nouveau récepteur du facteur de nécrose tumorale, et de protéines hybrides comprenant tout ou partie du TRH1 de l'invention.
CA002354612A 1998-12-11 1999-12-10 Homologue recepteur du facteur de necrose tumorale (trh1) Abandoned CA2354612A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11182698P 1998-12-11 1998-12-11
US60/111,826 1998-12-11
PCT/US1999/029400 WO2000034294A2 (fr) 1998-12-11 1999-12-10 Homologue recepteur du facteur de necrose tumorale (trh1)

Publications (1)

Publication Number Publication Date
CA2354612A1 true CA2354612A1 (fr) 2000-06-15

Family

ID=22340643

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002354612A Abandoned CA2354612A1 (fr) 1998-12-11 1999-12-10 Homologue recepteur du facteur de necrose tumorale (trh1)

Country Status (5)

Country Link
EP (1) EP1135412A2 (fr)
JP (1) JP2002531112A (fr)
AU (1) AU2708000A (fr)
CA (1) CA2354612A1 (fr)
WO (1) WO2000034294A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6358508B1 (en) 1997-06-11 2002-03-19 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor TR9
CN1329086A (zh) * 2000-06-21 2002-01-02 上海博德基因开发有限公司 一种新的多肽——人含细胞色素c结构域的tnfr/ngfr蛋白15和编码这种多肽的多核苷酸

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0869179A1 (fr) * 1997-04-02 1998-10-07 Smithkline Beecham Corporation Récepteur en rapport avec la nécrose des tumeurs, TR7
EP0988371A4 (fr) * 1997-06-11 2002-11-04 Human Genome Sciences Inc Recepteur humain tr9 du facteur de necrose tumorale

Also Published As

Publication number Publication date
EP1135412A2 (fr) 2001-09-26
AU2708000A (en) 2000-06-26
JP2002531112A (ja) 2002-09-24
WO2000034294A2 (fr) 2000-06-15
WO2000034294A3 (fr) 2000-10-26

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Legal Events

Date Code Title Description
FZDE Dead