CA2316545A1 - Nouvel acide nucleique et nouveau polypeptide - Google Patents

Nouvel acide nucleique et nouveau polypeptide Download PDF

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Publication number
CA2316545A1
CA2316545A1 CA002316545A CA2316545A CA2316545A1 CA 2316545 A1 CA2316545 A1 CA 2316545A1 CA 002316545 A CA002316545 A CA 002316545A CA 2316545 A CA2316545 A CA 2316545A CA 2316545 A1 CA2316545 A1 CA 2316545A1
Authority
CA
Canada
Prior art keywords
ntr
polypeptide
mammalian
human
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002316545A
Other languages
English (en)
Inventor
David M. Valenzuela
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Regeneron Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2316545A1 publication Critical patent/CA2316545A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La présente invention porte sur des séquences d'acide nucléique codant de nouveaux polypeptides récepteurs mammaliens appelés NTR-5. Cette invention porte également sur des systèmes de dosage pouvant être utilisés pour détecter et/ou mesurer des ligands qui fixent le produit génique mammalien NTR-5, ainsi que sur des méthodes diagnostiques et thérapeutiques basées sur l'interaction entre NTR-5 mammalien et des agents qui déclenchent la transduction du signal par fixation sur NTR-5. Selon une réalisation spécifique, NTR-5 mammalien peut être un NTR-5 humain ou de souris.
CA002316545A 1997-12-29 1998-12-28 Nouvel acide nucleique et nouveau polypeptide Abandoned CA2316545A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6892597P 1997-12-29 1997-12-29
US60/068,925 1997-12-29
PCT/US1998/027688 WO1999033967A2 (fr) 1997-12-29 1998-12-28 Nouvel acide nucleique et nouveau polypeptide

Publications (1)

Publication Number Publication Date
CA2316545A1 true CA2316545A1 (fr) 1999-07-08

Family

ID=22085585

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002316545A Abandoned CA2316545A1 (fr) 1997-12-29 1998-12-28 Nouvel acide nucleique et nouveau polypeptide

Country Status (6)

Country Link
EP (1) EP1044267A2 (fr)
JP (1) JP2002508934A (fr)
AU (1) AU748167B2 (fr)
CA (1) CA2316545A1 (fr)
IL (1) IL136988A0 (fr)
WO (1) WO1999033967A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU738688B2 (en) 1997-09-12 2001-09-27 Apoxis Sa Cysteine rich receptors-train
WO1999037818A1 (fr) * 1998-01-27 1999-07-29 Millennium Pharmaceuticals, Inc. Nouvelles molecules de la superfamille du recepteur du facteur de necrose tumorale et leurs utilisations
WO2000049149A1 (fr) * 1999-02-19 2000-08-24 Toshio Kitamura Nouvelles proteines du type recepteurs des tnf
US6951738B2 (en) 1999-07-16 2005-10-04 Human Genome Sciences, Inc. Human tumor necrosis factor receptors TR13 and TR14
AU780060B2 (en) * 1999-07-16 2005-02-24 Human Genome Sciences, Inc. Human tumor necrosis factor receptors TR13 and TR14
IL158152A0 (en) 2001-04-03 2004-03-28 Nestle Sa Osteoprotegerin in milk
WO2006017673A2 (fr) 2004-08-03 2006-02-16 Biogen Idec Ma Inc. Influence du taj sur les fonctions neuronales

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965388A (en) * 1996-07-09 1999-10-12 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
MA24169A1 (fr) * 1996-05-08 1997-12-31 Hoffmann La Roche Traitement de l'asthme a l'aide de la tnfr-ig
ATE397662T1 (de) * 1997-02-27 2008-06-15 Ono Pharmaceutical Co Neues polypeptid, dafür kodierende dna und deren verwendungen
WO1999011791A2 (fr) * 1997-09-05 1999-03-11 University Of Washington Recepteurs et ligands de la famille du facteur de necrose tumorale, acides nucleiques codants et agents de liaison associes
AU738688B2 (en) * 1997-09-12 2001-09-27 Apoxis Sa Cysteine rich receptors-train

Also Published As

Publication number Publication date
WO1999033967A3 (fr) 1999-09-10
JP2002508934A (ja) 2002-03-26
IL136988A0 (en) 2001-06-14
AU748167B2 (en) 2002-05-30
AU2207999A (en) 1999-07-19
EP1044267A2 (fr) 2000-10-18
WO1999033967A2 (fr) 1999-07-08

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 20041229