CA2354253A1 - Polypetides ou adices nucleiques codant les polypeptides de recepteurs couples de la famille des proteines g, et leur utilisation pour le diagnostic ou le traitement de troubles, notamment de troubles cutanes, et leur utilisation pour l'identification de substances pharmacologiquement actives - Google Patents
Polypetides ou adices nucleiques codant les polypeptides de recepteurs couples de la famille des proteines g, et leur utilisation pour le diagnostic ou le traitement de troubles, notamment de troubles cutanes, et leur utilisation pour l'identification de substances pharmacologiquement actives Download PDFInfo
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- CA2354253A1 CA2354253A1 CA002354253A CA2354253A CA2354253A1 CA 2354253 A1 CA2354253 A1 CA 2354253A1 CA 002354253 A CA002354253 A CA 002354253A CA 2354253 A CA2354253 A CA 2354253A CA 2354253 A1 CA2354253 A1 CA 2354253A1
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- Prior art keywords
- polypeptide
- nucleic acid
- wound healing
- acid encoding
- antibody
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- PTMHPRAIXMAOOB-UHFFFAOYSA-L phosphoramidate Chemical compound NP([O-])([O-])=O PTMHPRAIXMAOOB-UHFFFAOYSA-L 0.000 description 1
- 125000002743 phosphorus functional group Chemical group 0.000 description 1
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- 108010031719 prolyl-serine Proteins 0.000 description 1
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- 108010070643 prolylglutamic acid Proteins 0.000 description 1
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- 108010090894 prolylleucine Proteins 0.000 description 1
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- AQHHHDLHHXJYJD-UHFFFAOYSA-N propranolol Chemical compound C1=CC=C2C(OCC(O)CNC(C)C)=CC=CC2=C1 AQHHHDLHHXJYJD-UHFFFAOYSA-N 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 210000002307 prostate Anatomy 0.000 description 1
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- 238000004080 punching Methods 0.000 description 1
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- 108091008146 restriction endonucleases Proteins 0.000 description 1
- 102000029752 retinol binding Human genes 0.000 description 1
- 108091000053 retinol binding Proteins 0.000 description 1
- 230000001177 retroviral effect Effects 0.000 description 1
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- 239000002336 ribonucleotide Substances 0.000 description 1
- 108091092562 ribozyme Proteins 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
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- 230000019491 signal transduction Effects 0.000 description 1
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- 210000000273 spinal nerve root Anatomy 0.000 description 1
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- 230000008685 targeting Effects 0.000 description 1
- 208000002918 testicular germ cell tumor Diseases 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
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- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 238000009210 therapy by ultrasound Methods 0.000 description 1
- RYYWUUFWQRZTIU-UHFFFAOYSA-K thiophosphate Chemical compound [O-]P([O-])([O-])=S RYYWUUFWQRZTIU-UHFFFAOYSA-K 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
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- 230000032258 transport Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 230000004102 tricarboxylic acid cycle Effects 0.000 description 1
- 125000000430 tryptophan group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12 0.000 description 1
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- 241001430294 unidentified retrovirus Species 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Addiction (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Cardiology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Emergency Medicine (AREA)
- Oncology (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2000138111 DE10038111A1 (de) | 2000-08-04 | 2000-08-04 | Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren einer Familie von G-Protein gekoppelten Rezeptoren zur Diagnose oder Behandlung von Erkrankungen, beispielsweise Hautkrankheiten, sowie ihre Verwendung zur Identifizierung von pharmakologisch aktiven Substanzen |
| DE10038111.1 | 2000-08-04 | ||
| US22950100P | 2000-08-31 | 2000-08-31 | |
| US60/229,501 | 2000-08-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2354253A1 true CA2354253A1 (fr) | 2002-02-04 |
Family
ID=26006614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002354253A Abandoned CA2354253A1 (fr) | 2000-08-04 | 2001-07-31 | Polypetides ou adices nucleiques codant les polypeptides de recepteurs couples de la famille des proteines g, et leur utilisation pour le diagnostic ou le traitement de troubles, notamment de troubles cutanes, et leur utilisation pour l'identification de substances pharmacologiquement actives |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20020116724A1 (fr) |
| EP (1) | EP1178053A3 (fr) |
| JP (1) | JP2003000267A (fr) |
| AU (1) | AU5780801A (fr) |
| CA (1) | CA2354253A1 (fr) |
| IL (1) | IL144655A0 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040143092A1 (en) * | 2001-02-08 | 2004-07-22 | Alex Smolyar | Regulation of human dorsal root receptor-like g protein-coupled receptor |
| WO2003046147A2 (fr) * | 2001-11-26 | 2003-06-05 | Bristol-Myers Squibb Company | Nouveau recepteur couple a la proteine g humaine, hgprbmy31, variants et procedes d'utilisation de ce dernier |
| US20030171293A1 (en) * | 2002-02-27 | 2003-09-11 | Pfizer Inc. | Neuropeptide receptor and uses thereof |
| WO2004000999A2 (fr) * | 2002-06-21 | 2003-12-31 | California Institute Of Technology | Identification d'une migration regulee de recepteurs et metastase des cellules cancereuses de la peau |
| US7056685B1 (en) | 2002-11-05 | 2006-06-06 | Amgen Inc. | Receptor ligands and methods of modulating receptors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9704836D0 (sv) * | 1997-12-22 | 1997-12-22 | Astra Pharma Inc | Novel receptor |
| JP2000023676A (ja) * | 1998-07-14 | 2000-01-25 | Asahi Chem Ind Co Ltd | ７回膜貫通型受容体蛋白質ｅｒｇ５ |
| JP2000023677A (ja) * | 1998-07-14 | 2000-01-25 | Asahi Chem Ind Co Ltd | ７回膜貫通型受容体蛋白質ｅｒｇ９ |
| IL149569A0 (en) * | 1999-11-17 | 2002-11-10 | Arena Pharm Inc | Endogenous and non-endogenous versions of human g protein-coupled receptors |
| EP1242454A2 (fr) * | 1999-12-28 | 2002-09-25 | PHARMACIA & UPJOHN COMPANY | Nouveaux recepteurs couples a une proteine g |
| CA2399982A1 (fr) * | 2000-02-02 | 2001-08-09 | Incyte Genomics, Inc. | Recepteurs couples aux proteines g |
-
2001
- 2001-07-31 IL IL14465501A patent/IL144655A0/xx unknown
- 2001-07-31 CA CA002354253A patent/CA2354253A1/fr not_active Abandoned
- 2001-08-01 US US09/920,068 patent/US20020116724A1/en not_active Abandoned
- 2001-08-03 AU AU57808/01A patent/AU5780801A/en not_active Abandoned
- 2001-08-03 EP EP01118709A patent/EP1178053A3/fr not_active Withdrawn
- 2001-08-03 JP JP2001235814A patent/JP2003000267A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003000267A (ja) | 2003-01-07 |
| AU5780801A (en) | 2002-02-07 |
| EP1178053A2 (fr) | 2002-02-06 |
| US20020116724A1 (en) | 2002-08-22 |
| IL144655A0 (en) | 2002-05-23 |
| EP1178053A3 (fr) | 2002-03-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |