CA2352858A1 - Derives de swainsonine, procedes de preparation et utilisations comme agents therapeutiques - Google Patents

Derives de swainsonine, procedes de preparation et utilisations comme agents therapeutiques Download PDF

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Publication number
CA2352858A1
CA2352858A1 CA002352858A CA2352858A CA2352858A1 CA 2352858 A1 CA2352858 A1 CA 2352858A1 CA 002352858 A CA002352858 A CA 002352858A CA 2352858 A CA2352858 A CA 2352858A CA 2352858 A1 CA2352858 A1 CA 2352858A1
Authority
CA
Canada
Prior art keywords
compound
formula
compounds
aryl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002352858A
Other languages
English (en)
Inventor
Francois D. Tropper
Cheng Guo
Rajan N. Shah
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glycodesign Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2352858A1 publication Critical patent/CA2352858A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des dérivés de swainsonine 8a substitués, des procédés destinés à leur préparation, et leurs utilisations comme agents thérapeutiques. L'invention concerne aussi des compositions pharmaceutiques contenant ces composés ainsi que leurs utilisations comme agents thérapeutiques.
CA002352858A 1998-12-18 1999-12-17 Derives de swainsonine, procedes de preparation et utilisations comme agents therapeutiques Abandoned CA2352858A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11293098P 1998-12-18 1998-12-18
US60/112,930 1998-12-18
PCT/CA1999/001210 WO2000037465A2 (fr) 1998-12-18 1999-12-17 Derives de swainsonine, procedes de preparation et utilisations comme agents therapeutiques

Publications (1)

Publication Number Publication Date
CA2352858A1 true CA2352858A1 (fr) 2000-06-29

Family

ID=22346611

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002352858A Abandoned CA2352858A1 (fr) 1998-12-18 1999-12-17 Derives de swainsonine, procedes de preparation et utilisations comme agents therapeutiques

Country Status (3)

Country Link
AU (1) AU1764300A (fr)
CA (1) CA2352858A1 (fr)
WO (1) WO2000037465A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2286766A1 (fr) 1997-04-15 1998-10-22 Glycodesign Inc. Sels halogenes d'alcaloide de swainsonine et procedes d'utilisation
GB0401238D0 (en) * 2004-01-21 2004-02-25 Molecularnature Ltd Immunomodulatory alkaloids
CN102432609A (zh) * 2011-12-15 2012-05-02 西藏自治区农牧科学院 一种茎直黄芪中苦马豆素的微波辅助提取工艺
CN103319481B (zh) * 2013-07-05 2014-12-17 西藏自治区农牧科学院 茎直黄芪中苦马豆素的提取工艺

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5466809A (en) * 1991-11-06 1995-11-14 Toronto Research Chemicals, Inc. Process for the preparation of immunostimulating swainsonine analogs

Also Published As

Publication number Publication date
WO2000037465A3 (fr) 2000-09-08
WO2000037465A2 (fr) 2000-06-29
AU1764300A (en) 2000-07-12

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Legal Events

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