CA2345753A1 - Procede pour augmenter l'excretion des substances hydrophobes endogenes autres que les sterols en augmentant l'excretion fecale des matieres grasses - Google Patents

Procede pour augmenter l'excretion des substances hydrophobes endogenes autres que les sterols en augmentant l'excretion fecale des matieres grasses Download PDF

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Publication number
CA2345753A1
CA2345753A1 CA002345753A CA2345753A CA2345753A1 CA 2345753 A1 CA2345753 A1 CA 2345753A1 CA 002345753 A CA002345753 A CA 002345753A CA 2345753 A CA2345753 A CA 2345753A CA 2345753 A1 CA2345753 A1 CA 2345753A1
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CA
Canada
Prior art keywords
compound
excretion
fat
accumulation
faeces
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002345753A
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English (en)
Inventor
Hendrik Jan Verkade
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2345753A1 publication Critical patent/CA2345753A1/fr
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/739—Lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Cette invention se rapporte à un procédé servant à augmenter l'excrétion des substances hydrophobes endogènes autres que les stérols ou des dérivés métaboliques de cette substance, en augmentant l'excrétion fécale de ces substances hydrophobes ou des dérivés métaboliques de celles-ci, ce procédé se caractérisant en ce que l'excrétion fécale des matières grasses est accrue. Le but de cette invention est de prévenir ou de traiter les états associés à l'accumulation de substances hydrophobes endogènes autres que les stérols ou de dérivés métaboliques de ces substances, ces substances étant la bilirubine ou la protoporphyrine non conjuguée. Plus particulièrement, la lipstatine, l'orlistat, la tétrahydrolipstatine, les acides gras de polyol tels que l'olestra et les doses non habituelles de matières grasses diététiques sont utilisées pour traiter l'ictère physiologique du nouveau-né, l'ictère hémolytique et la protoporphyrie érythropoiétique.
CA002345753A 1999-07-30 1999-07-30 Procede pour augmenter l'excretion des substances hydrophobes endogenes autres que les sterols en augmentant l'excretion fecale des matieres grasses Abandoned CA2345753A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/NL1999/000492 WO2001008679A1 (fr) 1999-07-30 1999-07-30 Procede pour augmenter l'excretion des substances hydrophobes endogenes autres que les sterols en augmentant l'excretion fecale des matieres grasses

Publications (1)

Publication Number Publication Date
CA2345753A1 true CA2345753A1 (fr) 2001-02-08

Family

ID=19866607

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002345753A Abandoned CA2345753A1 (fr) 1999-07-30 1999-07-30 Procede pour augmenter l'excretion des substances hydrophobes endogenes autres que les sterols en augmentant l'excretion fecale des matieres grasses

Country Status (5)

Country Link
EP (1) EP1117396A1 (fr)
JP (1) JP2003505504A (fr)
AU (1) AU5200299A (fr)
CA (1) CA2345753A1 (fr)
WO (1) WO2001008679A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1216625A1 (fr) * 2000-12-21 2002-06-26 The Procter & Gamble Company Utilisation d'un lipide non-digestible, non-absorbable pour le traitement de l'hyperbilirubinémie
JP5697296B2 (ja) 2004-03-05 2015-04-08 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア 高脂血症および高コレステロール血症に関連する障害または疾患を、副作用を最小限にしつつ処置するための方法
US20130115306A1 (en) * 2011-11-09 2013-05-09 Denovo Inc. Toxin decontaminant food product and method of treating disorders of the gastrointestinal tract

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4363801A (en) * 1981-02-09 1982-12-14 The Texas A&M University System Method for treating hyperbilirubinemia
AU570143B2 (en) * 1985-01-14 1988-03-03 Rockefeller University, The Method of increasing heme excretion from a mammal using tin protoporphyrin
WO1989006137A1 (fr) * 1988-01-11 1989-07-13 Massachusetts Institute Of Technology Therapie orale de reduction de la bilirubine
US5665775A (en) * 1995-07-28 1997-09-09 Arab Pharmaceutical Manufacturing Co., Ltd. Different way of management of neonatal hyperbilirubinemia
JPH10330265A (ja) * 1997-06-02 1998-12-15 Lederle Japan Ltd 肝疾患治療剤

Also Published As

Publication number Publication date
JP2003505504A (ja) 2003-02-12
AU5200299A (en) 2001-02-19
WO2001008679A1 (fr) 2001-02-08
EP1117396A1 (fr) 2001-07-25

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 20050801