CA2343100A1 - Procede de fabrication de timbres matriciels autocollants contenant des sels hydrophiles de medicaments - Google Patents
Procede de fabrication de timbres matriciels autocollants contenant des sels hydrophiles de medicaments Download PDFInfo
- Publication number
- CA2343100A1 CA2343100A1 CA002343100A CA2343100A CA2343100A1 CA 2343100 A1 CA2343100 A1 CA 2343100A1 CA 002343100 A CA002343100 A CA 002343100A CA 2343100 A CA2343100 A CA 2343100A CA 2343100 A1 CA2343100 A1 CA 2343100A1
- Authority
- CA
- Canada
- Prior art keywords
- drug
- hci
- adhesive
- pressure sensitive
- sensitive adhesive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Un procédé de fabrication de timbre matriciel autocollant permettant d'administrer un médicament par voie transdermique est présentée. La méthode consiste à dissoudre le médicament sous forme de sel hydrophile dans la phase aqueuse d'une dispersion d'un autocollant hydrophobe, à couler le mélange qui en résulte en un film fin,et à faire évaporer l'eau. La stabilité physique du médicament dans le film est excellente et on évite toute crystallisation du médicament. Une méthode permettant d'augmenter le flux transdermique d'un médicament acide est également présentée.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14952398A | 1998-09-08 | 1998-09-08 | |
US09/149,523 | 1998-09-08 | ||
PCT/US1999/020814 WO2000024386A1 (fr) | 1998-09-08 | 1999-09-08 | Procede de fabrication de timbres matriciels autocollants contenant des sels hydrophiles de medicaments |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2343100A1 true CA2343100A1 (fr) | 2000-05-04 |
Family
ID=22530677
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002343100A Abandoned CA2343100A1 (fr) | 1998-09-08 | 1999-09-08 | Procede de fabrication de timbres matriciels autocollants contenant des sels hydrophiles de medicaments |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1117389A1 (fr) |
JP (1) | JP2003520191A (fr) |
AU (1) | AU5820699A (fr) |
CA (1) | CA2343100A1 (fr) |
WO (1) | WO2000024386A1 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE20220982U1 (de) * | 2001-03-16 | 2004-11-25 | Alza Corp., Mountain View | Transdermal-Pflaster zum Verabreichen von Fentanyl |
US7797375B2 (en) | 2001-05-07 | 2010-09-14 | International Business Machines Corporat | System and method for responding to resource requests in distributed computer networks |
DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
US20110086086A1 (en) * | 2005-07-26 | 2011-04-14 | Pfizer Inc | Transdermal system for varenicline |
WO2007035940A2 (fr) | 2005-09-23 | 2007-03-29 | Alza Corporation | Systeme d'administration de norelgestromine par voie transdermique |
WO2007035939A2 (fr) | 2005-09-23 | 2007-03-29 | Alza Corporation | Formulation de polyacrylate superieur avec chargement d'activateur destinee a des applications transdermiques |
KR101771629B1 (ko) * | 2008-03-31 | 2017-08-25 | 닛토덴코 가부시키가이샤 | 침투제 전달 시스템 및 그의 사용방법 |
US20100086582A1 (en) * | 2008-10-06 | 2010-04-08 | Mylan Technologies, Inc. | Amorphous rotigotine transdermal system |
FR2963889B1 (fr) | 2010-08-20 | 2013-04-12 | Debregeas Et Associes Pharma | Formulations a base de nalbuphine et leurs utilisations |
EP2809307B1 (fr) * | 2012-01-31 | 2017-12-20 | Grünenthal GmbH | Timbre pharmaceutique pour l'administration transdermique de (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine |
WO2014144109A1 (fr) * | 2013-03-15 | 2014-09-18 | Naimco, Inc. | Timbre transdermique ayant un adhésif non-soluble dans l'eau et un anesthésique |
WO2023048192A1 (fr) * | 2021-09-27 | 2023-03-30 | 久光製薬株式会社 | Procédé d'inhibition de production d'indolinones de diclofénac |
JP7222155B1 (ja) * | 2021-09-27 | 2023-02-14 | 久光製薬株式会社 | ジクロフェナクインドリノン体の生成を抑制する方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5310559A (en) * | 1982-09-01 | 1994-05-10 | Hercon Laboratories Corporation | Device for controlled release and delivery to mammalian tissue of pharmacologically active agents incorporating a rate controlling member which comprises an alkylene-alkyl acrylate copolymer |
US5633009A (en) * | 1990-11-28 | 1997-05-27 | Sano Corporation | Transdermal administration of azapirones |
JP2849950B2 (ja) * | 1990-11-30 | 1999-01-27 | 日東電工株式会社 | 経皮吸収製剤 |
US5883115A (en) * | 1992-11-09 | 1999-03-16 | Pharmetrix Division Technical Chemicals & Products, Inc. | Transdermal delivery of the eutomer of a chiral drug |
US5985317A (en) * | 1996-09-06 | 1999-11-16 | Theratech, Inc. | Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents |
EP1079813B1 (fr) * | 1998-04-29 | 2005-02-09 | Virotex Corporation | Dispositif porteur pharmaceutique pour l'administration de composes pharmaceutiques aux surfaces muqueuses |
-
1999
- 1999-09-08 WO PCT/US1999/020814 patent/WO2000024386A1/fr not_active Application Discontinuation
- 1999-09-08 CA CA002343100A patent/CA2343100A1/fr not_active Abandoned
- 1999-09-08 JP JP2000577996A patent/JP2003520191A/ja active Pending
- 1999-09-08 EP EP99945640A patent/EP1117389A1/fr not_active Withdrawn
- 1999-09-09 AU AU58206/99A patent/AU5820699A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1117389A1 (fr) | 2001-07-25 |
WO2000024386A1 (fr) | 2000-05-04 |
AU5820699A (en) | 2000-05-15 |
JP2003520191A (ja) | 2003-07-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Dead |