CA2334611A1 - Utilisation d'antagonistes du recepteur nk-1 dans le traitement des troubles psychiatriques - Google Patents
Utilisation d'antagonistes du recepteur nk-1 dans le traitement des troubles psychiatriques Download PDFInfo
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- CA2334611A1 CA2334611A1 CA002334611A CA2334611A CA2334611A1 CA 2334611 A1 CA2334611 A1 CA 2334611A1 CA 002334611 A CA002334611 A CA 002334611A CA 2334611 A CA2334611 A CA 2334611A CA 2334611 A1 CA2334611 A1 CA 2334611A1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La présente invention a pour objet l'utilisation d'un antagoniste du récepteur NK-1 dans la fabrication d'un médicament prévu pour être administré pour traiter ou prévenir les troubles dépressifs majeurs, les troubles anxieux sévères, les troubles dépressifs majeurs avec les troubles anxieux et les états de stress, sans thérapie parallèle par d'autres agents antidépressifs, anxiolytiques ou antistress. L'invention concerne également des procédés de traitement à l'aide d'un antagoniste du récepteur NK-1 et de compositions pharmaceutiques comprenant cet antagoniste.
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9812616.2 | 1998-06-11 | ||
| GBGB9812620.4A GB9812620D0 (en) | 1998-06-11 | 1998-06-11 | Therapeutic use |
| GB9812666.7 | 1998-06-11 | ||
| GBGB9812616.2A GB9812616D0 (en) | 1998-06-11 | 1998-06-11 | Therapeutic use |
| GB9812620.4 | 1998-06-11 | ||
| GBGB9812618.8A GB9812618D0 (en) | 1998-06-11 | 1998-06-11 | Therapeutic use |
| GBGB9812666.7A GB9812666D0 (en) | 1998-06-11 | 1998-06-11 | Therapeutic use |
| GB9812618.8 | 1998-06-11 | ||
| PCT/GB1999/001797 WO1999064006A1 (fr) | 1998-06-11 | 1999-06-08 | Utilisation d'antagonistes du recepteur nk-1 dans le traitement des troubles psychiatriques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2334611A1 true CA2334611A1 (fr) | 1999-12-16 |
Family
ID=27451798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002334611A Abandoned CA2334611A1 (fr) | 1998-06-11 | 1999-06-08 | Utilisation d'antagonistes du recepteur nk-1 dans le traitement des troubles psychiatriques |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1085873A1 (fr) |
| JP (1) | JP2002517446A (fr) |
| AU (1) | AU4278199A (fr) |
| CA (1) | CA2334611A1 (fr) |
| WO (1) | WO1999064006A1 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0020721D0 (en) * | 2000-08-22 | 2000-10-11 | Merck Sharp & Dohme | Therapeutic agents |
| JPWO2004026296A1 (ja) * | 2002-09-18 | 2006-01-12 | 味の素株式会社 | 抗ストレス性疾患組成物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9408442A (pt) * | 1993-12-29 | 1997-08-05 | Merck Sharp & Dohme | Composto composição farmacêutica processos para tratamento ou prevenção de distúrbios fisiológicos associados com um excesso de taquiquininas e para a preparação do composto e de uso do composto |
| CA2266773A1 (fr) * | 1996-10-07 | 1998-04-16 | Merck Sharp & Dohme Limited | Utilisation de l'antagoniste du recepteur nk-1 utilise comme antidepresseur et/ou agent anxiolytique |
| WO1998024440A1 (fr) * | 1996-12-02 | 1998-06-11 | Merck Sharp & Dohme Limited | Utilisation d'antagonistes du recepteur nk-1 dans le traitement des etats de stress |
| EP0942734A1 (fr) * | 1996-12-02 | 1999-09-22 | MERCK SHARP & DOHME LTD. | Utilisation d'antagonistes du recepteur nk-1 dans le traitement des etats anxieux severes |
| JP2001504847A (ja) * | 1996-12-02 | 2001-04-10 | メルク シヤープ エンド ドーム リミテツド | 重抑鬱障害の治療のためのｎｋ−１受容体拮抗薬の使用 |
| ATE282416T1 (de) * | 1996-12-02 | 2004-12-15 | Merck Sharp & Dohme | Die verwendung von nk-1 rezeptor antagonisten für die behandlung von substanz-verwendung störungen |
| EP0941093B1 (fr) * | 1996-12-02 | 2005-02-09 | MERCK SHARP & DOHME LTD. | Utilisation d'antagonistes du recepteur nk-1 dans le traitement des etats depressifs majeurs accompagnes d'anxiete |
-
1999
- 1999-06-08 CA CA002334611A patent/CA2334611A1/fr not_active Abandoned
- 1999-06-08 EP EP99955423A patent/EP1085873A1/fr not_active Withdrawn
- 1999-06-08 JP JP2000553075A patent/JP2002517446A/ja not_active Withdrawn
- 1999-06-08 WO PCT/GB1999/001797 patent/WO1999064006A1/fr not_active Application Discontinuation
- 1999-06-08 AU AU42781/99A patent/AU4278199A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU4278199A (en) | 1999-12-30 |
| JP2002517446A (ja) | 2002-06-18 |
| WO1999064006A1 (fr) | 1999-12-16 |
| EP1085873A1 (fr) | 2001-03-28 |
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| Date | Code | Title | Description |
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| FZDE | Dead |