CA2334609A1 - Utilisation d'un antagoniste du recepteur nk-1 dans le traitement des troubles psychiatriques - Google Patents
Utilisation d'un antagoniste du recepteur nk-1 dans le traitement des troubles psychiatriques Download PDFInfo
- Publication number
- CA2334609A1 CA2334609A1 CA002334609A CA2334609A CA2334609A1 CA 2334609 A1 CA2334609 A1 CA 2334609A1 CA 002334609 A CA002334609 A CA 002334609A CA 2334609 A CA2334609 A CA 2334609A CA 2334609 A1 CA2334609 A1 CA 2334609A1
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- Canada
- Prior art keywords
- treatment
- disorders
- pharmaceutically acceptable
- hydroxyethoxy
- triazol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 229960002324 trifluoperazine Drugs 0.000 description 1
- ZEWQUBUPAILYHI-UHFFFAOYSA-N trifluoperazine Chemical compound C1CN(C)CCN1CCCN1C2=CC(C(F)(F)F)=CC=C2SC2=CC=CC=C21 ZEWQUBUPAILYHI-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La présente invention concerne l'utilisation d'un antagoniste du récepteur NK-1 (neurokinine 1) pour la fabrication d'un médicament, administrable par voie orale, intervenant dans le traitement ou la prévention de troubles schizophréniques, de troubles liés à l'utilisation de certaines substances et de troubles de la mobilité ainsi que des techniques de traitement médical au moyen d'un tel antagoniste du récepteur NK-1 et des compositions pharmaceutiques et des produits renfermant ledit antagoniste.
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9812669.1 | 1998-06-11 | ||
| GB9812663.4 | 1998-06-11 | ||
| GBGB9812663.4A GB9812663D0 (en) | 1998-06-11 | 1998-06-11 | Therapeutic use |
| GB9812661.8 | 1998-06-11 | ||
| GBGB9812661.8A GB9812661D0 (en) | 1998-06-11 | 1998-06-11 | Therapeutic use |
| GBGB9812669.1A GB9812669D0 (en) | 1998-06-11 | 1998-06-11 | Therapeutic use |
| PCT/GB1999/001819 WO1999064010A1 (fr) | 1998-06-11 | 1999-06-08 | Utilisation d'un antagoniste du recepteur nk-1 dans le traitement des troubles psychiatriques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2334609A1 true CA2334609A1 (fr) | 1999-12-16 |
Family
ID=27269359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002334609A Abandoned CA2334609A1 (fr) | 1998-06-11 | 1999-06-08 | Utilisation d'un antagoniste du recepteur nk-1 dans le traitement des troubles psychiatriques |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1085875A1 (fr) |
| JP (1) | JP2002517448A (fr) |
| AU (1) | AU4279699A (fr) |
| CA (1) | CA2334609A1 (fr) |
| WO (1) | WO1999064010A1 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0020721D0 (en) * | 2000-08-22 | 2000-10-11 | Merck Sharp & Dohme | Therapeutic agents |
| DE10111058A1 (de) * | 2001-03-08 | 2002-09-12 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und NK¶1¶-Rezeptor-Antagonisten |
| US6620438B2 (en) | 2001-03-08 | 2003-09-16 | Boehringer Ingelheim Pharma Kg | Pharmaceutical compositions based on anticholinergics and NK1-receptor antagonists |
| US20060030600A1 (en) * | 2004-08-06 | 2006-02-09 | Patrick Schnider | Dual NK1/NK3 receptor antagonists for the treatment of schizophrenia |
| WO2006043532A1 (fr) * | 2004-10-19 | 2006-04-27 | Ono Pharmaceutical Co., Ltd. | Agent thérapeutique pour la maladie de parkinson |
| WO2009109001A1 (fr) * | 2008-03-04 | 2009-09-11 | Adelaide Research & Innovation Pty Ltd | Procédé de prévention et/ou de traitement d’une maladie, d’une condition ou d’un état associés à une fonction réduite des neurones dopaminergiques |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1462450B1 (fr) * | 1993-12-29 | 2007-06-13 | MERCK SHARP & DOHME LTD. | Dérivés de morpholine substitués et leur application en tant qu'agents thérapeutiques |
| GB9523244D0 (en) * | 1995-11-14 | 1996-01-17 | Merck Sharp & Dohme | Therapeutic agents |
| DK0942729T3 (da) * | 1996-12-02 | 2005-01-10 | Merck Sharp & Dohme | Anvendelse af NK-1-receptorantagonister til behandling af stresslidelser |
| ATE288756T1 (de) * | 1996-12-02 | 2005-02-15 | Merck Sharp & Dohme | Verwendung von nk-1 rezeptorantagonisten zur behandlung von schweren depressionen, die von angstzuständen begleitet werden |
| WO1998024445A1 (fr) * | 1996-12-02 | 1998-06-11 | Merck Sharp & Dohme Limited | Utilisation d'antagonistes du recepteur nk-1 dans le traitement des troubles schizophreniques |
| CA2273785A1 (fr) * | 1996-12-02 | 1998-06-11 | Raymond Baker | Utilisation d'antagonistes du recepteur nk-1 dans le traitement des etats anxieux severes |
| CA2273810A1 (fr) * | 1996-12-02 | 1998-06-11 | Merck Sharp & Dohme Limited | Utilisation d'antagonistes du recepteur nk-1 dans le traitement des etats depressifs majeurs |
| CA2273856A1 (fr) * | 1996-12-02 | 1998-06-11 | Merck Sharp & Dohme Limited | Utilisation d'antagonistes du recepteur nk-1 dans le traitement des troubles bipolaires |
| CA2273806A1 (fr) * | 1996-12-02 | 1998-06-11 | Merck Sharp & Dohme Limited | Utilisation d'antagonistes du recepteur nk-1 dans le traitement des troubles du sevrage |
-
1999
- 1999-06-08 EP EP99955427A patent/EP1085875A1/fr not_active Withdrawn
- 1999-06-08 WO PCT/GB1999/001819 patent/WO1999064010A1/fr not_active Application Discontinuation
- 1999-06-08 AU AU42796/99A patent/AU4279699A/en not_active Abandoned
- 1999-06-08 JP JP2000553079A patent/JP2002517448A/ja not_active Withdrawn
- 1999-06-08 CA CA002334609A patent/CA2334609A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU4279699A (en) | 1999-12-30 |
| WO1999064010A1 (fr) | 1999-12-16 |
| JP2002517448A (ja) | 2002-06-18 |
| EP1085875A1 (fr) | 2001-03-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |