CA2333107A1 - Produit pharmaceutique, procede et dispositif de realisation - Google Patents

Produit pharmaceutique, procede et dispositif de realisation Download PDF

Info

Publication number
CA2333107A1
CA2333107A1 CA002333107A CA2333107A CA2333107A1 CA 2333107 A1 CA2333107 A1 CA 2333107A1 CA 002333107 A CA002333107 A CA 002333107A CA 2333107 A CA2333107 A CA 2333107A CA 2333107 A1 CA2333107 A1 CA 2333107A1
Authority
CA
Canada
Prior art keywords
substrate
powder
product according
deposition
product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002333107A
Other languages
English (en)
Inventor
Lawrence Harrison Hammer
Howard Christopher Rivenburg
Nitin Vithalbhai Desai
Kerry Dennis O'mara
Suggy S. Chrai
William Ronald Roach
Hoi Cheong Sun
Peter John Zanzucchi
Eugene Samuel Poliniak
Jen-Chi Chen
Bawa Singh
Nalin Kumar
Aaron William Levine
Prince Lal
Peter David Southgate
Ramaswamy Murari
David Keller
Dominic Stephen Rosati
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Delsys Pharmaceutical Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/095,246 external-priority patent/US6063194A/en
Priority claimed from US09/095,616 external-priority patent/US6303143B1/en
Application filed by Individual filed Critical Individual
Publication of CA2333107A1 publication Critical patent/CA2333107A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B1/04—Methods of, or means for, filling the material into the containers or receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B1/30—Devices or methods for controlling or determining the quantity or quality or the material fed or filled
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B11/00—Wrapping, e.g. partially or wholly enclosing, articles or quantities of material, in strips, sheets or blanks, of flexible material
    • B65B11/50—Enclosing articles, or quantities of material, by disposing contents between two sheets, e.g. pocketed sheets, and securing their opposed free margins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/08—Plant for applying liquids or other fluent materials to objects

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mechanical Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Quality & Reliability (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Electrostatic Spraying Apparatus (AREA)
  • Medicinal Preparation (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

La présente invention concerne un produit (1) pharmaceutique, en l'occurrence une monodose thérapeutique ou une dose de diagnostic (6) comprenant une quantité définie d'un principe actif ne s'écartant pas de plus de 5% de la quantité définie. Selon une réalisation, la monodose est constituée d'un substrat (8), d'un dépôt (14) sur le substrat, et d'une couche (9) qui recouvre le dépôt et qui est fixée au substrat par une liaison encerclant le dépôt et donc encapsulant le dépôt entre le substrat et les substrats de couverture. Le dépôt renferme une poudre dont une partie au moins est constituée du principe actif considéré. La monodose est obtenue au moyen d'un appareil de dépôt de poudre sèche qui procède à un dépôt électrostatique de la poudre sur le substrat. Cet appareil qui fait intervenir un mandrin électrostatique et un appareil de débit de poudre chargée, comporte également un appareil capable de mesurer la quantité de poudre déposée.
CA002333107A 1998-06-10 1999-06-08 Produit pharmaceutique, procede et dispositif de realisation Abandoned CA2333107A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/095,246 US6063194A (en) 1998-06-10 1998-06-10 Dry powder deposition apparatus
US09/095,616 US6303143B1 (en) 1998-06-10 1998-06-10 Pharmaceutical product
US09/095,616 1998-06-10
US09/095,246 1998-06-10
PCT/US1999/012772 WO1999063972A1 (fr) 1998-06-10 1999-06-08 Produit pharmaceutique, procede et dispositif de realisation

Publications (1)

Publication Number Publication Date
CA2333107A1 true CA2333107A1 (fr) 1999-12-16

Family

ID=26789996

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002333107A Abandoned CA2333107A1 (fr) 1998-06-10 1999-06-08 Produit pharmaceutique, procede et dispositif de realisation

Country Status (10)

Country Link
EP (1) EP1089721A1 (fr)
JP (1) JP2002517304A (fr)
KR (1) KR20010052734A (fr)
CN (1) CN1312709A (fr)
AU (1) AU763869B2 (fr)
CA (1) CA2333107A1 (fr)
HU (1) HUP0102753A2 (fr)
IL (1) IL140087A0 (fr)
NZ (1) NZ508402A (fr)
WO (1) WO1999063972A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6287595B1 (en) * 1998-06-10 2001-09-11 Delsys Pharmaceuticals Corporation Biomedical assay device
US6444033B1 (en) * 1999-11-12 2002-09-03 Delsys Pharmaceutical Corp. Article comprising a diffuser with flow control features
KR20030023692A (ko) * 2000-07-06 2003-03-19 델시스 파머수티컬 코포레이션 상승된 안정성을 갖는 의약품의 제형화 방법
US6411567B1 (en) * 2000-07-07 2002-06-25 Mark A. Niemiec Drug delivery management system
IL154268A0 (en) * 2000-08-10 2003-09-17 Delsys Pharmaceutical Corp Improved solid pharmaceutical dosage formulation of hydrophobic drugs
TWI356036B (en) * 2004-06-09 2012-01-11 Smithkline Beecham Corp Apparatus and method for pharmaceutical production
US8814861B2 (en) 2005-05-12 2014-08-26 Innovatech, Llc Electrosurgical electrode and method of manufacturing same
TWI636715B (zh) * 2017-11-10 2018-09-21 台光電子材料股份有限公司 取粉裝置

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4332789A (en) * 1975-12-15 1982-06-01 Hoffmann-La Roche Inc. Pharmaceutical unit dosage forms
GB2154365A (en) * 1984-02-10 1985-09-04 Philips Electronic Associated Loading semiconductor wafers on an electrostatic chuck
US5669973A (en) 1995-06-06 1997-09-23 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing and retaining materials upon a substrate
US5714007A (en) 1995-06-06 1998-02-03 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing a medicament powder upon predefined regions of a substrate
US5753302A (en) 1996-04-09 1998-05-19 David Sarnoff Research Center, Inc. Acoustic dispenser
US5846595A (en) 1996-04-09 1998-12-08 Sarnoff Corporation Method of making pharmaceutical using electrostatic chuck
US5788814A (en) 1996-04-09 1998-08-04 David Sarnoff Research Center Chucks and methods for positioning multiple objects on a substrate
US5871010A (en) 1996-06-10 1999-02-16 Sarnoff Corporation Inhaler apparatus with modified surfaces for enhanced release of dry powders
US5858814A (en) 1996-07-17 1999-01-12 Lucent Technologies Inc. Hybrid chip and method therefor

Also Published As

Publication number Publication date
NZ508402A (en) 2003-08-29
WO1999063972A1 (fr) 1999-12-16
AU763869B2 (en) 2003-07-31
AU4675599A (en) 1999-12-30
JP2002517304A (ja) 2002-06-18
KR20010052734A (ko) 2001-06-25
WO1999063972A9 (fr) 2000-10-12
IL140087A0 (en) 2002-02-10
HUP0102753A2 (hu) 2001-11-28
EP1089721A1 (fr) 2001-04-11
CN1312709A (zh) 2001-09-12

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JP2003514736A (ja) 流れ制御機能を備えたディフューザを有する装置
US6844048B2 (en) Substrates for powder deposition containing conductive domains
AU2083600A (en) Electrostatic chucks
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Legal Events

Date Code Title Description
FZDE Discontinued