CA2322858C - Detection of analytes by fluorescent lanthanide chelates - Google Patents

Detection of analytes by fluorescent lanthanide chelates Download PDF

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Publication number
CA2322858C
CA2322858C CA002322858A CA2322858A CA2322858C CA 2322858 C CA2322858 C CA 2322858C CA 002322858 A CA002322858 A CA 002322858A CA 2322858 A CA2322858 A CA 2322858A CA 2322858 C CA2322858 C CA 2322858C
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CA
Canada
Prior art keywords
lanthanide metal
analyte
chelators
group
ligand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002322858A
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English (en)
French (fr)
Other versions
CA2322858A1 (en
Inventor
Edwin F. Ullman
Alexandre V. Nikolaitchik
George Y. Daniloff
David Parker
Arthur E. Colvin
Aristotle G. Kalivretenos
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Sensors for Medecine and Science Inc
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Sensors for Medecine and Science Inc
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Publication of CA2322858A1 publication Critical patent/CA2322858A1/en
Application granted granted Critical
Publication of CA2322858C publication Critical patent/CA2322858C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/06Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]
    • Y10T436/144444Glucose

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Materials Engineering (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
CA002322858A 1998-03-11 1999-03-11 Detection of analytes by fluorescent lanthanide chelates Expired - Fee Related CA2322858C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3796098A 1998-03-11 1998-03-11
US09/037,960 1998-03-11
PCT/US1999/005290 WO1999046600A1 (en) 1998-03-11 1999-03-11 Detection of analytes by fluorescent lanthanide chelates

Publications (2)

Publication Number Publication Date
CA2322858A1 CA2322858A1 (en) 1999-09-16
CA2322858C true CA2322858C (en) 2009-06-02

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA002322858A Expired - Fee Related CA2322858C (en) 1998-03-11 1999-03-11 Detection of analytes by fluorescent lanthanide chelates

Country Status (9)

Country Link
US (1) US6344360B1 (https=)
EP (1) EP1062516A1 (https=)
JP (1) JP4625180B2 (https=)
KR (1) KR100718953B1 (https=)
CN (1) CN1159583C (https=)
AU (1) AU757901B2 (https=)
CA (1) CA2322858C (https=)
TW (1) TWI227323B (https=)
WO (1) WO1999046600A1 (https=)

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US6673625B2 (en) 1999-09-15 2004-01-06 The Regents Of The University Of California Saccharide sensing molecules having enhanced fluorescent properties
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WO2001075450A2 (en) * 2000-04-04 2001-10-11 The Regents Of The University Of California Fluorescent lifetime assays for non-invasive quantification of analytes
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US7470420B2 (en) * 2000-12-05 2008-12-30 The Regents Of The University Of California Optical determination of glucose utilizing boronic acid adducts
US6653141B2 (en) * 2000-12-05 2003-11-25 The Regents Of The University Of California Polyhydroxyl-substituted organic molecule sensing method and device
US6800451B2 (en) * 2001-01-05 2004-10-05 Sensors For Medicine And Science, Inc. Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone
US20020119581A1 (en) * 2001-01-05 2002-08-29 Daniloff George Y. Detection of analytes
US6927246B2 (en) 2001-02-15 2005-08-09 Medtronic Minimed, Inc. Polymers functionalized with fluorescent boronate motifs and methods for making them
JP4729734B2 (ja) * 2001-05-16 2011-07-20 財団法人北九州産業学術推進機構 キドセンサによる重金属イオン測定装置
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US9493806B2 (en) 2001-06-01 2016-11-15 Colorado State University Research Foundation Enzymatic biosensing systems
US20050164316A1 (en) * 2001-06-27 2005-07-28 Bray Terry L. Biophotonic sensors and methods of use thereof
US20030215391A1 (en) * 2001-07-19 2003-11-20 Carlos Rabito Fluorescent agents for real-time measurement of organ function
US7045361B2 (en) 2001-09-12 2006-05-16 Medtronic Minimed, Inc. Analyte sensing via acridine-based boronate biosensors
ATE468335T1 (de) * 2002-03-14 2010-06-15 Sensors For Med & Science Inc Nachweis von glucose in lösungen, die auch alpha- hydroxysäure oder ein beta-diketon enthalten
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JP4748791B2 (ja) * 2003-02-24 2011-08-17 独立行政法人科学技術振興機構 蛍光性ランタニド錯体
WO2005065241A2 (en) * 2003-12-24 2005-07-21 Argose, Inc. Smmr (small molecule metabolite reporters) for use as in vivo glucose biosensors
US7713745B2 (en) * 2004-04-13 2010-05-11 Sensors For Medicine And Science, Inc. Non-covalent immobilization of indicator molecules
DE102004051830B4 (de) * 2004-10-25 2007-12-13 Roche Diagnostics Gmbh Multifunktionales Referenzsystem bei Analytbestimmungen durch Fluoreszenz
TWI381162B (zh) * 2005-05-26 2013-01-01 Plagenom Co Ltd A authenticity determination method, an authenticity determination device, a authenticity determination system, and a detection device terminal
JP5057682B2 (ja) * 2006-03-30 2012-10-24 株式会社東芝 照明装置、撮像装置及び携帯端末
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CN104641232A (zh) * 2012-04-24 2015-05-20 阿克森斯公司 用于表征和/或测定样品的方法
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Also Published As

Publication number Publication date
EP1062516A1 (en) 2000-12-27
US6344360B1 (en) 2002-02-05
TWI227323B (en) 2005-02-01
CA2322858A1 (en) 1999-09-16
CN1300368A (zh) 2001-06-20
KR100718953B1 (ko) 2007-05-16
CN1159583C (zh) 2004-07-28
WO1999046600A1 (en) 1999-09-16
WO1999046600A9 (en) 1999-11-18
AU757901B2 (en) 2003-03-13
AU3078599A (en) 1999-09-27
KR20010041855A (ko) 2001-05-25
JP4625180B2 (ja) 2011-02-02
JP2002506973A (ja) 2002-03-05

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Effective date: 20160311