CA2316405A1 - Modulation de l'inflammation a l'aide de produits du type protease - Google Patents

Modulation de l'inflammation a l'aide de produits du type protease Download PDF

Info

Publication number
CA2316405A1
CA2316405A1 CA002316405A CA2316405A CA2316405A1 CA 2316405 A1 CA2316405 A1 CA 2316405A1 CA 002316405 A CA002316405 A CA 002316405A CA 2316405 A CA2316405 A CA 2316405A CA 2316405 A1 CA2316405 A1 CA 2316405A1
Authority
CA
Canada
Prior art keywords
mcp
cells
host
gelatinise
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002316405A
Other languages
English (en)
Inventor
Ian Clark-Lewis
Jiang-Hong Gong
G. Angus Mcquibban
Christopher Mark Overall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
University of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA 2307705 external-priority patent/CA2307705A1/fr
Application filed by University of British Columbia filed Critical University of British Columbia
Priority to CA002316405A priority Critical patent/CA2316405A1/fr
Priority to PCT/CA2001/000741 priority patent/WO2001090361A2/fr
Priority to AU2001261971A priority patent/AU2001261971A1/en
Publication of CA2316405A1 publication Critical patent/CA2316405A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • C07K14/523Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002316405A 2000-05-26 2000-08-17 Modulation de l'inflammation a l'aide de produits du type protease Abandoned CA2316405A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002316405A CA2316405A1 (fr) 2000-05-26 2000-08-17 Modulation de l'inflammation a l'aide de produits du type protease
PCT/CA2001/000741 WO2001090361A2 (fr) 2000-05-26 2001-05-25 Modulation des effets de protease sur des substrats de chimiokines
AU2001261971A AU2001261971A1 (en) 2000-05-26 2001-05-25 Modulation of inflammation by protease-treated mcp-3 chemokine

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA 2307705 CA2307705A1 (fr) 2000-05-26 2000-05-26 Modulation de l'inflammation a l'aide de produits du type protease
CA2,307,705 2000-05-26
CA002316405A CA2316405A1 (fr) 2000-05-26 2000-08-17 Modulation de l'inflammation a l'aide de produits du type protease

Publications (1)

Publication Number Publication Date
CA2316405A1 true CA2316405A1 (fr) 2001-11-26

Family

ID=25681785

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002316405A Abandoned CA2316405A1 (fr) 2000-05-26 2000-08-17 Modulation de l'inflammation a l'aide de produits du type protease

Country Status (3)

Country Link
AU (1) AU2001261971A1 (fr)
CA (1) CA2316405A1 (fr)
WO (1) WO2001090361A2 (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998006751A1 (fr) * 1996-08-16 1998-02-19 Research Corporation Technologies, Inc. Antagonistes des recepteurs de mcp-3, rantes et mip-1alpha
EP0906954A1 (fr) * 1997-09-29 1999-04-07 Applied Research Systems ARS Holding N.V. C-C chémokine tronquée à l'aminoterminus comme antagoniste de chémokines

Also Published As

Publication number Publication date
AU2001261971A1 (en) 2001-12-03
WO2001090361A2 (fr) 2001-11-29
WO2001090361A3 (fr) 2002-08-08

Similar Documents

Publication Publication Date Title
EP1061944B1 (fr) Antagonistes therapeutiques du recepteur de chemokine
DE60103052T2 (de) Verwendung von cxcr4 antagonisten zur behandlung von krebs und autoimmunkrankheiten
US6875738B1 (en) Therapeutic chemokine receptor antagonists
KR100898765B1 (ko) 성장인자 복합체
KR20080082608A (ko) Vegf 유사체 및 사용 방법
US20090192082A1 (en) Cxcr4 antagonist treatment of hematopoietic cells
JP2009515520A (ja) 肝細胞成長因子イントロン融合蛋白
KR100682666B1 (ko) 항혈관형성 단백질 및 이들을 사용하는 방법
DE60106002T2 (de) Behandlung von hämatopoetischen Zellen mit CXCR4 Agonisten
WO2000009152A1 (fr) Antagonistes therapeutiques du recepteur de la chimiokine
JP2018535964A (ja) 線維芽細胞増殖因子(fgf)1アナログによるステロイド誘導性高血糖の処置
JP2001510988A (ja) プロテアーゼ活性化受容体3およびその使用
JP2009019032A (ja) 血管形成及び心臓血管新生の促進又は阻害
KR101008785B1 (ko) 유사분열촉진 활성을 가진 Bv8 핵산 및 폴리펩티드
WO1997035969A2 (fr) Ligands peptidiques du recepteur de l'urokinase
Spiller et al. Modulation of human CXCL12 binding properties to glycosaminoglycans to enhance chemotactic gradients
US20050164929A1 (en) Methods of preventing and treating inflammatory bowel disease
CA2316405A1 (fr) Modulation de l'inflammation a l'aide de produits du type protease
US20070059314A1 (en) Novel anti-angiogenic agent and its use in particular within the framework of the treatment of cancer
JPH05271291A (ja) 機能性ポリペプチド
CA2307705A1 (fr) Modulation de l'inflammation a l'aide de produits du type protease
KR100568755B1 (ko) Yh 모티프를 포함하는 펩타이드를 유효성분으로함유하는 혈관신생 억제제
EP2504027B1 (fr) Accélération de la cicatrisation par un inhibiteur tissulaire des métalloprotéases lié à des ancres de glycosylphosphatidylinositol (gpi)
JP2002543784A (ja) 新規なチンパンジーエリスロポエチン(chepo)ポリペプチドおよびこれをコードする核酸
US20040029775A1 (en) Methods and compounds for influencing beta3-integrin-dependent intracellular processes

Legal Events

Date Code Title Description
FZDE Dead