CA2315263A1 - Reactifs et methodes s'utilisant pour detecter des affections du pancreas - Google Patents

Reactifs et methodes s'utilisant pour detecter des affections du pancreas Download PDF

Info

Publication number
CA2315263A1
CA2315263A1 CA002315263A CA2315263A CA2315263A1 CA 2315263 A1 CA2315263 A1 CA 2315263A1 CA 002315263 A CA002315263 A CA 002315263A CA 2315263 A CA2315263 A CA 2315263A CA 2315263 A1 CA2315263 A1 CA 2315263A1
Authority
CA
Canada
Prior art keywords
sequence
polynucleotide
polypeptide
antigen
fragments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002315263A
Other languages
English (en)
Inventor
Patricia A. Billing-Medel
Maurice Cohen
Tracey L. Colpitts
Paula N. Friedman
Julian Gordon
Edward N. Granados
Steven C. Hodges
Michael R. Klass
Jon D. Kratochvil
Lisa Roberts-Rapp
John C. Russell
Stephen D. Stroupe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2315263A1 publication Critical patent/CA2315263A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne une série de séquences d'ADN complémentaire contiguës et se chevauchant en partie, ainsi que des polypeptides codés par ces séquences dénommées PA153 et transcrites à partir de tissu pancréatique. Ces séquences s'utilisent pour la détection, le diagnostic, la stadification, le contrôle, le pronostic, la formation d'images in vivo, la prévention ou le traitement, ou la détermination de la prédisposition d'un individu à des affections et troubles du pancréas tels que le cancer du pancréas. L'invention concerne également des anticorps se liant spécifiquement au polypeptide ou à la protéine codée par PA153, ainsi que des agonistes ou inhibiteurs empêchant l'action du polypeptide PA153 spécifique au tissu, ces molécules s'utilisant pour le traitement thérapeutique de maladies, tumeurs ou métastases du pancréas.
CA002315263A 1997-12-15 1998-12-11 Reactifs et methodes s'utilisant pour detecter des affections du pancreas Abandoned CA2315263A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99056897A 1997-12-15 1997-12-15
US08/990,568 1997-12-15
PCT/US1998/026441 WO1999031274A2 (fr) 1997-12-15 1998-12-11 Reactifs et methodes s'utilisant pour detecter des affections du pancreas

Publications (1)

Publication Number Publication Date
CA2315263A1 true CA2315263A1 (fr) 1999-06-24

Family

ID=25536289

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002315263A Abandoned CA2315263A1 (fr) 1997-12-15 1998-12-11 Reactifs et methodes s'utilisant pour detecter des affections du pancreas

Country Status (3)

Country Link
EP (1) EP1038030A2 (fr)
CA (1) CA2315263A1 (fr)
WO (1) WO1999031274A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002534088A (ja) * 1999-01-07 2002-10-15 インサイト・ファーマスーティカルズ・インコーポレイテッド インスリン合成遺伝子
US7034132B2 (en) 2001-06-04 2006-04-25 Anderson David W Therapeutic polypeptides, nucleic acids encoding same, and methods of use
CN1703524B (zh) * 2002-09-30 2010-04-07 肿瘤疗法科学股份有限公司 与人胰腺癌相关的基因和多肽

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996021041A1 (fr) * 1994-12-29 1996-07-11 Eiken Kagaku Kabushiki Kaisha Procede de detection cellulaire
US5998165A (en) * 1995-12-29 1999-12-07 Incyte Pharmaceuticals, Inc. Polynucleotides encoding a protein associated with pancreatic cancer
US5817479A (en) * 1996-08-07 1998-10-06 Incyte Pharmaceuticals, Inc. Human kinase homologs

Also Published As

Publication number Publication date
EP1038030A2 (fr) 2000-09-27
WO1999031274A2 (fr) 1999-06-24
WO1999031274A3 (fr) 1999-09-02

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Legal Events

Date Code Title Description
FZDE Discontinued