CA2309559A1 - Hp90: host membrane receptor for pathogenic bacteria, encoded by the bacterial tir gene - Google Patents

Hp90: host membrane receptor for pathogenic bacteria, encoded by the bacterial tir gene Download PDF

Info

Publication number
CA2309559A1
CA2309559A1 CA002309559A CA2309559A CA2309559A1 CA 2309559 A1 CA2309559 A1 CA 2309559A1 CA 002309559 A CA002309559 A CA 002309559A CA 2309559 A CA2309559 A CA 2309559A CA 2309559 A1 CA2309559 A1 CA 2309559A1
Authority
CA
Canada
Prior art keywords
tir
polypeptide
polynucleotide
coli
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002309559A
Other languages
English (en)
French (fr)
Inventor
B. Brett Finlay
Brendan Kenny
Rebekah Devinney
Marcus Stein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2309559A1 publication Critical patent/CA2309559A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA002309559A 1997-11-12 1998-11-10 Hp90: host membrane receptor for pathogenic bacteria, encoded by the bacterial tir gene Abandoned CA2309559A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6513097P 1997-11-12 1997-11-12
US60/065,130 1997-11-12
PCT/CA1998/001042 WO1999024576A1 (en) 1997-11-12 1998-11-10 Hp90: host membrane receptor for pathogenic bacteria, encoded by the bacterial tir gene

Publications (1)

Publication Number Publication Date
CA2309559A1 true CA2309559A1 (en) 1999-05-20

Family

ID=22060539

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002309559A Abandoned CA2309559A1 (en) 1997-11-12 1998-11-10 Hp90: host membrane receptor for pathogenic bacteria, encoded by the bacterial tir gene

Country Status (9)

Country Link
EP (1) EP1029054B1 (enExample)
JP (2) JP4410412B2 (enExample)
AT (1) ATE438721T1 (enExample)
AU (1) AU1137399A (enExample)
CA (1) CA2309559A1 (enExample)
DE (1) DE69841042D1 (enExample)
ES (1) ES2333630T3 (enExample)
PT (1) PT1029054E (enExample)
WO (1) WO1999024576A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9901897D0 (en) * 1999-01-29 1999-03-17 Imp College Innovations Ltd Biological material and use thereof
GB0013115D0 (en) * 2000-05-31 2000-07-19 Imp College Innovations Ltd Biological materials and methods for use in the prevention or treatment of infections
WO2002053181A1 (en) 2001-01-04 2002-07-11 University Of Saskatchewan Enterohemorragic escherichia coli vaccine
CA2339436A1 (fr) 2001-03-15 2002-09-15 Josee Harel Production d'anticorps contre les facteurs de virulence associes aux souches d'escherichia coli aeec, et leur utilisation
CN1922324B (zh) 2003-10-31 2010-06-09 不列颠哥伦比亚大学 细菌毒力因子及其用途
US8414903B2 (en) 2006-11-29 2013-04-09 Tufts University Escherichia coli mutants and methods of use thereof
WO2010115278A1 (en) 2009-04-06 2010-10-14 University Of Saskatchewan Methods and compositions for treating and preventing shiga toxin-producing escherichia coli infection
AU2014225717B2 (en) * 2013-03-07 2019-01-17 President And Fellows Of Harvard College Compositions and methods for bacterial delivery of polypeptides
US10702559B2 (en) 2016-02-09 2020-07-07 The General Hospital Corporation Methods and compositions relating to engineered microbial cells

Also Published As

Publication number Publication date
ES2333630T3 (es) 2010-02-24
EP1029054B1 (en) 2009-08-05
DE69841042D1 (de) 2009-09-17
JP2009173667A (ja) 2009-08-06
JP2001522605A (ja) 2001-11-20
PT1029054E (pt) 2009-11-11
JP4410412B2 (ja) 2010-02-03
EP1029054A1 (en) 2000-08-23
ATE438721T1 (de) 2009-08-15
AU1137399A (en) 1999-05-31
WO1999024576A1 (en) 1999-05-20

Similar Documents

Publication Publication Date Title
US8021861B2 (en) Pathogenic Escherichia coli associated protein
Konkel et al. Identification and molecular cloning of a gene encoding a fibronectin‐binding protein (CadF) from Campylobacter jejuni
De Grado et al. Identification of the intimin‐binding domain of Tir of enteropathogenic Escherichia coli
JP2009173667A (ja) 病原菌のｔｉｒ遺伝子によってコードされる、病原菌の宿主の膜受容体、ｈｐ９０
Alm et al. Variation in antigenicity and molecular weight of Campylobacter coli VC167 flagellin in different genetic backgrounds
US7026157B1 (en) Bacterial hemoglobin receptor genes
WO2003065973A2 (en) Multivalent streptococcal vaccine compositions and methods for use
US5874300A (en) Campylobacter jejuni antigens and methods for their production and use
JP2000509270A (ja) ヒスチジンタグ付きインチミン、ならびに免疫応答を刺激し、標的能力を有する抗原担体としてインチミンを使用する方法
EP2417165B1 (en) Methods and compositions for treating and preventing shiga toxin-producing escherichia coli infection
US20070298014A1 (en) Probiotic therapy of neonatal meningitis and method of using E. coli virulence determinants
KR0170752B1 (ko) 혈호균속 인플루엔자용 백신과 진단검사법
WO1999045136A1 (en) Methods for assaying type iii secretion inhibitors
US7208574B1 (en) Host receptor for pathogenic bacteria
Moeck et al. Topological analysis of the Escherichia coli ferrichrome-iron receptor by using monoclonal antibodies
US6890539B2 (en) Genes and proteins, and their use
WO2002079247A2 (en) Intimins in the prevention or treatment of infections:ii
EP1366068A1 (en) Poynucleotide and polypeptide from group b streptococcus and use thereof for the preparation of a vaccine
MXPA98008795A (es) Proteina asociada con escherichia coli patogena

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20150417