JP4410412B2 - 病原菌のｔｉｒ遺伝子によってコードされる、病原菌の宿主の膜受容体、ｈｐ９０ - Google Patents

病原菌のｔｉｒ遺伝子によってコードされる、病原菌の宿主の膜受容体、ｈｐ９０ Download PDF

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Publication number
JP4410412B2
JP4410412B2 JP2000520570A JP2000520570A JP4410412B2 JP 4410412 B2 JP4410412 B2 JP 4410412B2 JP 2000520570 A JP2000520570 A JP 2000520570A JP 2000520570 A JP2000520570 A JP 2000520570A JP 4410412 B2 JP4410412 B2 JP 4410412B2
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Japan
Prior art keywords
tir
polypeptide
polynucleotide
epec
intimin
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English (en)
Japanese (ja)
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JP2001522605A5 (enExample
JP2001522605A (ja
Inventor
フィンレイ，ビー．，ブレット
ケニー，ブレンダン
デビニー，レベッカ
ステイン，マーカス
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ザ ユニバーシティー オブ ブリティッシュ コロンビア
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Publication of JP2001522605A5 publication Critical patent/JP2001522605A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2000520570A 1997-11-12 1998-11-10 病原菌のｔｉｒ遺伝子によってコードされる、病原菌の宿主の膜受容体、ｈｐ９０ Expired - Fee Related JP4410412B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6513097P 1997-11-12 1997-11-12
US60/065,130 1997-11-12
PCT/CA1998/001042 WO1999024576A1 (en) 1997-11-12 1998-11-10 Hp90: host membrane receptor for pathogenic bacteria, encoded by the bacterial tir gene

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009071999A Division JP2009173667A (ja) 1997-11-12 2009-03-24 病原菌のｔｉｒ遺伝子によってコードされる、病原菌の宿主の膜受容体、ｈｐ９０

Publications (3)

Publication Number Publication Date
JP2001522605A JP2001522605A (ja) 2001-11-20
JP2001522605A5 JP2001522605A5 (enExample) 2006-01-12
JP4410412B2 true JP4410412B2 (ja) 2010-02-03

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ID=22060539

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000520570A Expired - Fee Related JP4410412B2 (ja) 1997-11-12 1998-11-10 病原菌のｔｉｒ遺伝子によってコードされる、病原菌の宿主の膜受容体、ｈｐ９０
JP2009071999A Pending JP2009173667A (ja) 1997-11-12 2009-03-24 病原菌のｔｉｒ遺伝子によってコードされる、病原菌の宿主の膜受容体、ｈｐ９０

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009071999A Pending JP2009173667A (ja) 1997-11-12 2009-03-24 病原菌のｔｉｒ遺伝子によってコードされる、病原菌の宿主の膜受容体、ｈｐ９０

Country Status (9)

Country Link
EP (1) EP1029054B1 (enExample)
JP (2) JP4410412B2 (enExample)
AT (1) ATE438721T1 (enExample)
AU (1) AU1137399A (enExample)
CA (1) CA2309559A1 (enExample)
DE (1) DE69841042D1 (enExample)
ES (1) ES2333630T3 (enExample)
PT (1) PT1029054E (enExample)
WO (1) WO1999024576A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9901897D0 (en) * 1999-01-29 1999-03-17 Imp College Innovations Ltd Biological material and use thereof
GB0013115D0 (en) * 2000-05-31 2000-07-19 Imp College Innovations Ltd Biological materials and methods for use in the prevention or treatment of infections
BR0206312A (pt) 2001-01-04 2004-02-17 Univ Saskatchewan Composição de vacina, uso sobrenadante de cultura celular de escherichia coli enteroemorrágica (ehec), e, métodos para a geração de uma resposta imunológica em um mamìfero contra um antìgeno de escherichia coli enteroemorrágica (ehec) secretado, e 0157:h7 enteroemorrágica (ehec 0157:h7) secretado, e para a redução da colonização de escherichia coli enteroemorrágica (ehec) em um ruminante
CA2339436A1 (fr) 2001-03-15 2002-09-15 Josee Harel Production d'anticorps contre les facteurs de virulence associes aux souches d'escherichia coli aeec, et leur utilisation
CN101711861A (zh) 2003-10-31 2010-05-26 不列颠哥伦比亚大学 细菌毒力因子及其用途
WO2008133659A2 (en) 2006-11-29 2008-11-06 Tufts University Eschericia coli mutants and methods of use thereof
US8734811B2 (en) 2009-04-06 2014-05-27 University Of Saskatchewan Methods and compositions for treating and preventing Shiga toxin-producing Escherichia coli infection
CA2904009A1 (en) * 2013-03-07 2014-09-12 The General Hospital Corporation Compositions and methods for bacterial delivery of polypeptides
US10702559B2 (en) 2016-02-09 2020-07-07 The General Hospital Corporation Methods and compositions relating to engineered microbial cells

Also Published As

Publication number Publication date
JP2009173667A (ja) 2009-08-06
EP1029054A1 (en) 2000-08-23
ATE438721T1 (de) 2009-08-15
ES2333630T3 (es) 2010-02-24
PT1029054E (pt) 2009-11-11
EP1029054B1 (en) 2009-08-05
WO1999024576A1 (en) 1999-05-20
CA2309559A1 (en) 1999-05-20
AU1137399A (en) 1999-05-31
DE69841042D1 (de) 2009-09-17
JP2001522605A (ja) 2001-11-20

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