CA2307316C - Kcnq2 and kcnq3-potassium channel genes which are mutated in benign familial neonatal convulsions (bfnc) and other epilepsies - Google Patents
Kcnq2 and kcnq3-potassium channel genes which are mutated in benign familial neonatal convulsions (bfnc) and other epilepsies Download PDFInfo
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- CA2307316C CA2307316C CA2307316A CA2307316A CA2307316C CA 2307316 C CA2307316 C CA 2307316C CA 2307316 A CA2307316 A CA 2307316A CA 2307316 A CA2307316 A CA 2307316A CA 2307316 C CA2307316 C CA 2307316C
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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Priority Applications (1)
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|---|---|---|---|
| CA2712809A CA2712809C (en) | 1997-10-24 | 1998-10-23 | Kcnq2 and kcnq3-potassium channel genes which are mutated in benign familial neonatal convulsions (bfnc) and other epilepsies |
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| US6314797P | 1997-10-24 | 1997-10-24 | |
| US60/063,147 | 1997-10-24 | ||
| PCT/US1998/022375 WO1999021875A1 (en) | 1997-10-24 | 1998-10-23 | Kcnq2 and kcnq3-potassium channel genes which are mutated in benign familial neonatal convulsions (bfnc) and other epilepsies |
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| CA2712809A Division CA2712809C (en) | 1997-10-24 | 1998-10-23 | Kcnq2 and kcnq3-potassium channel genes which are mutated in benign familial neonatal convulsions (bfnc) and other epilepsies |
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| ES2281129T3 (es) | 1997-08-12 | 2007-09-16 | Bristol-Myers Squibb Company | Canales de potasio kcnq y procedimientos para su modulacion. |
| US6413719B1 (en) * | 1997-10-24 | 2002-07-02 | University Of Utah Research Foundation | KCNQ2 and KCNQ3-potassium channel genes which are mutated in benign familial neonatal convulsions (BFNC) and other epilepsies |
| DK1147134T3 (da) * | 1999-01-26 | 2007-02-05 | Neurosearch As | Hidtil ukendte kaliumkanaler og gener, der koder for disse kaliumkanaler |
| US6794161B1 (en) | 1999-01-26 | 2004-09-21 | Neurosearch A/S | Potassium channels and genes encoding these potassium channels |
| AU4911000A (en) * | 1999-06-11 | 2001-01-02 | Neurosearch A/S | Novel potassium channels and genes encoding these potassium channels |
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| GB9915414D0 (en) * | 1999-07-01 | 1999-09-01 | Glaxo Group Ltd | Medical use |
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| AU1846501A (en) | 1999-11-26 | 2001-06-04 | Bionomics Limited | Loci for idiopathic generalized epilepsy, mutations thereof and method using same to assess, diagnose, prognose or treat epilepsy |
| US6617131B2 (en) | 2000-03-21 | 2003-09-09 | Aventis Pharma Deutschland Gmbh | Nucleic acid molecule encoding the potassium channel protein, KCNQ5 |
| DE10013732A1 (de) * | 2000-03-21 | 2001-09-27 | Aventis Pharma Gmbh | Das Kaliumkanalprotein KCNQ5, ein neuer Angriffspunkt bei Erkrankungen des zentralen Nervensystems und des Herz-Kreislauf-Systems |
| US6348486B1 (en) * | 2000-10-17 | 2002-02-19 | American Home Products Corporation | Methods for modulating bladder function |
| US7537928B2 (en) * | 2003-08-22 | 2009-05-26 | Masonic Medical Research Laboratory | Mutations in ion channel proteins associated with sudden cardiac death |
| WO2005035784A1 (en) * | 2003-10-13 | 2005-04-21 | Bionomics Limited | A diagnostic method for neonatal or infantile epilepsy syndromes |
| WO2006096648A2 (en) * | 2005-03-07 | 2006-09-14 | University Of Utah Research Foundation | Mouse model |
| KR102361394B1 (ko) * | 2017-12-28 | 2022-02-14 | 재단법인 대구경북과학기술원 | 뇌전증과 관련된 ｍｉＲＮＡ 및 그의 용도 |
| KR102248910B1 (ko) * | 2017-12-28 | 2021-05-06 | 재단법인대구경북과학기술원 | 뇌전증과 관련된 ｍｉＲＮＡ 및 그의 용도 |
| CN111499758B (zh) * | 2019-01-31 | 2023-01-31 | 中国科学院脑科学与智能技术卓越创新中心 | 筛选人钾离子通道调节剂的方法 |
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| US5833975A (en) | 1989-03-08 | 1998-11-10 | Virogenetics Corporation | Canarypox virus expressing cytokine and/or tumor-associated antigen DNA sequence |
| US4675285A (en) * | 1984-09-19 | 1987-06-23 | Genetics Institute, Inc. | Method for identification and isolation of DNA encoding a desired protein |
| JPH09502614A (ja) | 1993-09-14 | 1997-03-18 | メルク エンド カンパニー インコーポレーテッド | 新規ヒト蛋白質チロシンホスファターゼをコードするｃＤＮＡ |
| JP3619282B2 (ja) | 1994-04-01 | 2005-02-09 | 中外製薬株式会社 | ＩｇＧＦｃ部結合タンパク質をコードする遺伝子 |
| ES2325820T3 (es) * | 1995-12-22 | 2009-09-18 | University Of Utah Research Foundation | Gen del sindrome qt largo que codifica kvlqt1 y su asociacion con mink. |
| JPH09191882A (ja) * | 1996-01-16 | 1997-07-29 | Japan Tobacco Inc | ヒト新規ｋ＋チャネル蛋白質をコードするｄｎａおよびその断片 |
| ES2281129T3 (es) * | 1997-08-12 | 2007-09-16 | Bristol-Myers Squibb Company | Canales de potasio kcnq y procedimientos para su modulacion. |
| US6413719B1 (en) | 1997-10-24 | 2002-07-02 | University Of Utah Research Foundation | KCNQ2 and KCNQ3-potassium channel genes which are mutated in benign familial neonatal convulsions (BFNC) and other epilepsies |
| GB9726339D0 (en) * | 1997-12-13 | 1998-02-11 | Zeneca Ltd | Human-derived tissue-specific potassium channel |
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1998
- 1998-10-23 US US09/177,650 patent/US6413719B1/en not_active Expired - Lifetime
- 1998-10-23 EP EP98955051A patent/EP1037900A4/en not_active Withdrawn
- 1998-10-23 JP JP2000517983A patent/JP4520634B2/ja not_active Expired - Lifetime
- 1998-10-23 CA CA2307316A patent/CA2307316C/en not_active Expired - Lifetime
- 1998-10-23 WO PCT/US1998/022375 patent/WO1999021875A1/en not_active Ceased
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2002
- 2002-03-14 US US10/096,578 patent/US7214483B2/en not_active Expired - Fee Related
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2007
- 2007-02-05 US US11/702,218 patent/US9523127B2/en not_active Expired - Fee Related
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2009
- 2009-10-16 JP JP2009239501A patent/JP5328603B2/ja not_active Expired - Lifetime
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- 2013-05-29 JP JP2013112986A patent/JP5911823B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20070254297A1 (en) | 2007-11-01 |
| JP2001521041A (ja) | 2001-11-06 |
| WO1999021875A1 (en) | 1999-05-06 |
| WO1999021875A9 (en) | 1999-08-12 |
| EP1037900A1 (en) | 2000-09-27 |
| JP5328603B2 (ja) | 2013-10-30 |
| CA2307316A1 (en) | 1999-05-06 |
| US20030165874A1 (en) | 2003-09-04 |
| US6413719B1 (en) | 2002-07-02 |
| US7214483B2 (en) | 2007-05-08 |
| JP4520634B2 (ja) | 2010-08-11 |
| JP2010075182A (ja) | 2010-04-08 |
| US9523127B2 (en) | 2016-12-20 |
| EP1037900A4 (en) | 2006-08-30 |
| JP2013226146A (ja) | 2013-11-07 |
| JP5911823B2 (ja) | 2016-04-27 |
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