CA2304102A1 - Polypeptide de type insuline et ses utilisations - Google Patents

Polypeptide de type insuline et ses utilisations Download PDF

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Publication number
CA2304102A1
CA2304102A1 CA002304102A CA2304102A CA2304102A1 CA 2304102 A1 CA2304102 A1 CA 2304102A1 CA 002304102 A CA002304102 A CA 002304102A CA 2304102 A CA2304102 A CA 2304102A CA 2304102 A1 CA2304102 A1 CA 2304102A1
Authority
CA
Canada
Prior art keywords
ilp
polypeptide
seq
insulin
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002304102A
Other languages
English (en)
Inventor
Austin L. Gurney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2304102A1 publication Critical patent/CA2304102A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/64—Relaxins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne des séquences nucléotidiques et d'acides aminés destinées à identifier et à coder un nouveau polypeptide exprimé de type insuline (ILP), exprimé par exemple à partir de cellules du colon ou de l'utérus. La présente invention concerne également les molécules antisens desdites séquences nucléotidiques codant l'ILP, des vecteurs d'expression permettant de produire un ILP purifié, des anticorps capables de se fixer spécifiquement à cet ILP, des sondes d'hybridation ou des oligonucléotides conçus pour détecter les séquences d'acide nucléique codant l'ILP, des cellules hôtes génétiquement manipulées permettant d'exprimer l'ILP, des tests destinés à diagnostiquer l'activation de type insuline en fonction des molécules d'acide nucléique codant l'ILP, et des anticorps capables de se fixer spécifiquement à la protéine.
CA002304102A 1997-09-24 1998-08-28 Polypeptide de type insuline et ses utilisations Abandoned CA2304102A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5983697P 1997-09-24 1997-09-24
US60/059,836 1997-09-24
PCT/US1998/017888 WO1999015664A1 (fr) 1997-09-24 1998-08-28 Polypeptide de type insuline et ses utilisations

Publications (1)

Publication Number Publication Date
CA2304102A1 true CA2304102A1 (fr) 1999-04-01

Family

ID=22025596

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002304102A Abandoned CA2304102A1 (fr) 1997-09-24 1998-08-28 Polypeptide de type insuline et ses utilisations

Country Status (7)

Country Link
EP (1) EP1017816A1 (fr)
JP (1) JP2001517444A (fr)
AU (1) AU9037898A (fr)
CA (1) CA2304102A1 (fr)
IL (1) IL135050A0 (fr)
WO (1) WO1999015664A1 (fr)
ZA (1) ZA988070B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111269310A (zh) * 2020-03-02 2020-06-12 郑州伊美诺生物技术有限公司 C-p串联表达重组蛋白及其基因、制备方法、应用、c肽检测试剂盒

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3228500A (en) * 1999-02-12 2000-08-29 Zymogenetics Inc. Insulin-family homolog localized to chromosome 1
CN1633498A (zh) * 2000-04-21 2005-06-29 武田药品工业株式会社 新型胰岛素/胰岛素样生长因子/松弛素家族多肽及其dna
SE526214C2 (sv) * 2003-02-28 2005-07-26 Amersham Biosciences Ab Ett sätt att generera metallkelaterande affinitetsligander

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5108897A (en) * 1988-09-30 1992-04-28 Cornell Research Foundation, Inc. Relaxin testing for early detection of pregnancy in dogs
US6046028A (en) * 1996-10-15 2000-04-04 Zymogenetics, Inc. Polynucleotides encoding insulin homolog zins3

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111269310A (zh) * 2020-03-02 2020-06-12 郑州伊美诺生物技术有限公司 C-p串联表达重组蛋白及其基因、制备方法、应用、c肽检测试剂盒
CN111269310B (zh) * 2020-03-02 2023-03-31 郑州伊美诺生物技术有限公司 C-p串联表达重组蛋白及其基因、制备方法、应用、c肽检测试剂盒

Also Published As

Publication number Publication date
WO1999015664A1 (fr) 1999-04-01
IL135050A0 (en) 2001-05-20
AU9037898A (en) 1999-04-12
ZA988070B (en) 2000-03-03
JP2001517444A (ja) 2001-10-09
EP1017816A1 (fr) 2000-07-12

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued