EP1017816A1 - Polypeptide de type insuline et ses utilisations - Google Patents

Polypeptide de type insuline et ses utilisations

Info

Publication number
EP1017816A1
EP1017816A1 EP98942285A EP98942285A EP1017816A1 EP 1017816 A1 EP1017816 A1 EP 1017816A1 EP 98942285 A EP98942285 A EP 98942285A EP 98942285 A EP98942285 A EP 98942285A EP 1017816 A1 EP1017816 A1 EP 1017816A1
Authority
EP
European Patent Office
Prior art keywords
ilp
polypeptide
seq
cell
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98942285A
Other languages
German (de)
English (en)
Inventor
Austin Gurney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of EP1017816A1 publication Critical patent/EP1017816A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/64—Relaxins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne des séquences nucléotidiques et d'acides aminés destinées à identifier et à coder un nouveau polypeptide exprimé de type insuline (ILP), exprimé par exemple à partir de cellules du colon ou de l'utérus. La présente invention concerne également les molécules antisens desdites séquences nucléotidiques codant l'ILP, des vecteurs d'expression permettant de produire un ILP purifié, des anticorps capables de se fixer spécifiquement à cet ILP, des sondes d'hybridation ou des oligonucléotides conçus pour détecter les séquences d'acide nucléique codant l'ILP, des cellules hôtes génétiquement manipulées permettant d'exprimer l'ILP, des tests destinés à diagnostiquer l'activation de type insuline en fonction des molécules d'acide nucléique codant l'ILP, et des anticorps capables de se fixer spécifiquement à la protéine.
EP98942285A 1997-09-24 1998-08-28 Polypeptide de type insuline et ses utilisations Withdrawn EP1017816A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5983697P 1997-09-24 1997-09-24
US59836P 1997-09-24
PCT/US1998/017888 WO1999015664A1 (fr) 1997-09-24 1998-08-28 Polypeptide de type insuline et ses utilisations

Publications (1)

Publication Number Publication Date
EP1017816A1 true EP1017816A1 (fr) 2000-07-12

Family

ID=22025596

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98942285A Withdrawn EP1017816A1 (fr) 1997-09-24 1998-08-28 Polypeptide de type insuline et ses utilisations

Country Status (7)

Country Link
EP (1) EP1017816A1 (fr)
JP (1) JP2001517444A (fr)
AU (1) AU9037898A (fr)
CA (1) CA2304102A1 (fr)
IL (1) IL135050A0 (fr)
WO (1) WO1999015664A1 (fr)
ZA (1) ZA988070B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3228500A (en) * 1999-02-12 2000-08-29 Zymogenetics Inc. Insulin-family homolog localized to chromosome 1
KR20020093053A (ko) * 2000-04-21 2002-12-12 다케다 야쿠힌 고교 가부시키가이샤 신규 인슐린/ｉｇｆ/릴랙신 패밀리 폴리펩티드 및 그의ｄｎａ
SE526214C2 (sv) * 2003-02-28 2005-07-26 Amersham Biosciences Ab Ett sätt att generera metallkelaterande affinitetsligander
CN111269310B (zh) * 2020-03-02 2023-03-31 郑州伊美诺生物技术有限公司 C-p串联表达重组蛋白及其基因、制备方法、应用、c肽检测试剂盒

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5108897A (en) * 1988-09-30 1992-04-28 Cornell Research Foundation, Inc. Relaxin testing for early detection of pregnancy in dogs
WO1998016635A1 (fr) * 1996-10-15 1998-04-23 Zymogenetics, Inc. Homologues de l'insuline

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9915664A1 *

Also Published As

Publication number Publication date
AU9037898A (en) 1999-04-12
JP2001517444A (ja) 2001-10-09
ZA988070B (en) 2000-03-03
CA2304102A1 (fr) 1999-04-01
WO1999015664A1 (fr) 1999-04-01
IL135050A0 (en) 2001-05-20

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Legal Events

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Effective date: 20000413

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Withdrawal date: 20011022