CA2300972A1 - Utilisation de l'element mariner pour creer des animaux transgeniques - Google Patents
Utilisation de l'element mariner pour creer des animaux transgeniques Download PDFInfo
- Publication number
- CA2300972A1 CA2300972A1 CA002300972A CA2300972A CA2300972A1 CA 2300972 A1 CA2300972 A1 CA 2300972A1 CA 002300972 A CA002300972 A CA 002300972A CA 2300972 A CA2300972 A CA 2300972A CA 2300972 A1 CA2300972 A1 CA 2300972A1
- Authority
- CA
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- Prior art keywords
- mariner
- transposase
- cell
- avian
- embryo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Environmental Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Animal Husbandry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Developmental Biology & Embryology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
L'invention concerne un procédé pour créer un embryon d'animal transgénique. Ce procédé consiste à introduire, dans une cellule embryonnaire de l'animal, un élément semblable au Mariner (MLA) qui comprend un transgène, et éventuellement à introduire une protéine transposase exogène ou une séquence d'ADN ou d'ARN codant pour une transposase. On peut utiliser l'embryon qui résulte de cette opération pour produire de nouveaux embryons ou pour lui permettre de se développer et donner un animal. L'invention peut servir à introduire des ADN étrangers dans des animaux sélectionnés.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9717913.9A GB9717913D0 (en) | 1997-08-22 | 1997-08-22 | Dna |
| GBGB9812822.6A GB9812822D0 (en) | 1998-06-12 | 1998-06-12 | Dna |
| GB9812822.6 | 1998-06-12 | ||
| GB9717913.9 | 1998-06-12 | ||
| PCT/GB1998/002517 WO1999009817A1 (fr) | 1997-08-22 | 1998-08-21 | Utilisation de l'element mariner pour creer des animaux transgeniques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2300972A1 true CA2300972A1 (fr) | 1999-03-04 |
Family
ID=26312117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002300972A Abandoned CA2300972A1 (fr) | 1997-08-22 | 1998-08-21 | Utilisation de l'element mariner pour creer des animaux transgeniques |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1006790A1 (fr) |
| JP (1) | JP2001513336A (fr) |
| AU (1) | AU8817798A (fr) |
| CA (1) | CA2300972A1 (fr) |
| WO (1) | WO1999009817A1 (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6299850B1 (en) | 1999-03-16 | 2001-10-09 | The United States Of America As Represented By The Department Of Energy | Carbon activation process for increased surface accessibility in electrochemical capacitors |
| EP1161551A2 (fr) * | 1999-03-17 | 2001-12-12 | Paradigm Genetics Inc. | Methodes et materiaux de production elevee et rapide d'une bibliotheque de genes knockouts dans un organisme |
| WO2001029205A2 (fr) * | 1999-10-19 | 2001-04-26 | Minos Biosystems Limited | Procede de manipulation genetique |
| EP1268837B1 (fr) * | 2000-03-21 | 2009-07-15 | Minos Biosystems Limited | PROCEDE DE PRODUCTION de MAMMIFERES TRANSGENIQUES A L'AIDE DE TRANSPOSONS |
| JP2004267001A (ja) * | 2000-08-16 | 2004-09-30 | Kansai Tlo Kk | トランスジェニック哺乳動物及びその作製方法並びにこれを用いた遺伝子機能の解明方法 |
| US20030092179A1 (en) * | 2001-09-24 | 2003-05-15 | Patrick Fogarty | Animal integration vector and methods for its use |
| JP2005512602A (ja) | 2002-01-09 | 2005-05-12 | マイノス バイオシステムズ リミテッド | トランスポゾンベクターを使用するトランスジェニック生物における誘導性転位 |
| JP2005530516A (ja) * | 2002-06-26 | 2005-10-13 | トランスジェンアールエックス，インコーポレイテッド | トランスポゾンベースのベクターを使用したトランスジェニック動物における遺伝子調節 |
| US20040172667A1 (en) | 2002-06-26 | 2004-09-02 | Cooper Richard K. | Administration of transposon-based vectors to reproductive organs |
| FR2850668B1 (fr) * | 2003-01-31 | 2005-04-08 | Centre Nat Rech Scient | Elements genetiques mobiles appartenant a la famille mariner chez les eucaryotes hydrothermaux |
| WO2005003359A1 (fr) * | 2003-07-08 | 2005-01-13 | Japan Science And Technology Corporation | Procede et systeme permettant de mettre au point un organisme transgenique |
| WO2005062881A2 (fr) | 2003-12-24 | 2005-07-14 | Transgenrx, Inc. | Therapie genique faisant intervenir des vecteurs de transposon |
| US9157097B2 (en) | 2008-09-25 | 2015-10-13 | Proteovec Holding, L.L.C. | Vectors for production of growth hormone |
| WO2010036976A2 (fr) | 2008-09-25 | 2010-04-01 | Transgenrx, Inc. | Nouveaux vecteurs pour la production d'anticorps |
| EP2417263B1 (fr) | 2009-04-09 | 2015-09-23 | ProteoVec Holding L.L.C. | Production de protéines au moyen de vecteurs à base de transposon |
| BR112022018442A2 (pt) | 2020-03-15 | 2022-11-22 | Proteinea Inc | Produção de proteína recombinante em insetos |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8906214D0 (en) * | 1989-03-17 | 1989-05-04 | Nat Res Dev | Introducing an exogenous gene into birds |
| GB9517780D0 (en) * | 1995-08-31 | 1995-11-01 | Roslin Inst Edinburgh | Biological manipulation |
| EP0885307A1 (fr) * | 1996-02-09 | 1998-12-23 | Vereniging Het Nederlands Kanker Instituut | Vecteurs et methodes afferentes permettant d'apporter a des cellules des acides nucleiques supplementaires s'integrant dans leur genome |
-
1998
- 1998-08-21 WO PCT/GB1998/002517 patent/WO1999009817A1/fr not_active Application Discontinuation
- 1998-08-21 CA CA002300972A patent/CA2300972A1/fr not_active Abandoned
- 1998-08-21 EP EP98939777A patent/EP1006790A1/fr not_active Withdrawn
- 1998-08-21 JP JP2000507225A patent/JP2001513336A/ja active Pending
- 1998-08-21 AU AU88177/98A patent/AU8817798A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU8817798A (en) | 1999-03-16 |
| EP1006790A1 (fr) | 2000-06-14 |
| WO1999009817A1 (fr) | 1999-03-04 |
| JP2001513336A (ja) | 2001-09-04 |
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| FZDE | Discontinued |