CA2286733C - Reverse-turn mimetics and methods relating thereto - Google Patents
Reverse-turn mimetics and methods relating thereto Download PDFInfo
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- CA2286733C CA2286733C CA002286733A CA2286733A CA2286733C CA 2286733 C CA2286733 C CA 2286733C CA 002286733 A CA002286733 A CA 002286733A CA 2286733 A CA2286733 A CA 2286733A CA 2286733 C CA2286733 C CA 2286733C
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- compound
- turn
- amino acid
- mimetics
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/846,432 US6013458A (en) | 1995-10-27 | 1997-04-30 | Reverse-turn mimetics and methods relating thereto |
| US08/846,432 | 1997-04-30 | ||
| PCT/US1998/008542 WO1998049168A1 (en) | 1997-04-30 | 1998-04-28 | Reverse-turn mimetics and methods relating thereto |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2286733A1 CA2286733A1 (en) | 1998-11-05 |
| CA2286733C true CA2286733C (en) | 2004-07-20 |
Family
ID=25297917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002286733A Expired - Fee Related CA2286733C (en) | 1997-04-30 | 1998-04-28 | Reverse-turn mimetics and methods relating thereto |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6013458A (https=) |
| EP (1) | EP0980373A1 (https=) |
| JP (1) | JP2001526651A (https=) |
| KR (1) | KR20010020416A (https=) |
| AU (1) | AU743777B2 (https=) |
| CA (1) | CA2286733C (https=) |
| WO (1) | WO1998049168A1 (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6184223B1 (en) | 1995-10-27 | 2001-02-06 | Molecumetics Ltd. | Reverse-turn mimetics and methods relating thereto |
| AUPP254898A0 (en) * | 1998-03-24 | 1998-04-23 | University Of Queensland, The | Peptide turn mimetics |
| CA2376232A1 (en) * | 1999-06-14 | 2000-12-21 | Genentech, Inc. | A structured peptide scaffold for displaying turn libraries on phage |
| US20030166003A1 (en) * | 1999-06-14 | 2003-09-04 | Cochran Andrea G. | Structured peptide scaffold for displaying turn libraries on phage |
| US6294525B1 (en) * | 1999-09-01 | 2001-09-25 | Molecumetics Ltd. | Reverse-turn mimetics and methods relating thereto |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992013878A2 (en) * | 1991-02-07 | 1992-08-20 | Board Of Trustees Of The University Of Illinois | Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same |
| WO1994003494A1 (en) * | 1992-08-06 | 1994-02-17 | The Board Of Trustees Of The University Of Illinois | Conformationally restricted mimetics of reverse turns and peptides containing the same |
| US5288514A (en) * | 1992-09-14 | 1994-02-22 | The Regents Of The University Of California | Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support |
| US5886186A (en) * | 1995-10-25 | 1999-03-23 | Versicor, Inc. | Synthesis of substituted N-heteroaromatic compounds and methods of use thereof |
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1997
- 1997-04-30 US US08/846,432 patent/US6013458A/en not_active Expired - Lifetime
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1998
- 1998-04-28 AU AU71679/98A patent/AU743777B2/en not_active Ceased
- 1998-04-28 KR KR1019997010040A patent/KR20010020416A/ko not_active Ceased
- 1998-04-28 EP EP98918829A patent/EP0980373A1/en not_active Withdrawn
- 1998-04-28 WO PCT/US1998/008542 patent/WO1998049168A1/en not_active Ceased
- 1998-04-28 JP JP54729198A patent/JP2001526651A/ja active Pending
- 1998-04-28 CA CA002286733A patent/CA2286733C/en not_active Expired - Fee Related
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| EP0980373A1 (en) | 2000-02-23 |
| WO1998049168A1 (en) | 1998-11-05 |
| CA2286733A1 (en) | 1998-11-05 |
| US6013458A (en) | 2000-01-11 |
| JP2001526651A (ja) | 2001-12-18 |
| KR20010020416A (ko) | 2001-03-15 |
| AU7167998A (en) | 1998-11-24 |
| AU743777B2 (en) | 2002-02-07 |
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