CA2283280C - Reovirus for the treatment of neoplasia - Google Patents
Reovirus for the treatment of neoplasia Download PDFInfo
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- CA2283280C CA2283280C CA002283280A CA2283280A CA2283280C CA 2283280 C CA2283280 C CA 2283280C CA 002283280 A CA002283280 A CA 002283280A CA 2283280 A CA2283280 A CA 2283280A CA 2283280 C CA2283280 C CA 2283280C
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- reovirus
- neoplasm
- cells
- cancer
- ras
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12211—Orthoreovirus, e.g. mammalian orthoreovirus
- C12N2720/12232—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Landscapes
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CA002508238A CA2508238C (en) | 1997-08-13 | 1998-08-12 | Reovirus for the treatment of neoplasia |
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| US08/911,383 US6110461A (en) | 1997-08-13 | 1997-08-13 | Reovirus for the treatment of neoplasia |
| US08/911,383 | 1997-08-13 | ||
| PCT/CA1998/000774 WO1999008692A1 (en) | 1997-08-13 | 1998-08-12 | Reovirus for the treatment of neoplasia |
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| CA002508238A Division CA2508238C (en) | 1997-08-13 | 1998-08-12 | Reovirus for the treatment of neoplasia |
Publications (2)
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| CA2283280A1 CA2283280A1 (en) | 1999-02-25 |
| CA2283280C true CA2283280C (en) | 2005-10-18 |
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| CA002283280A Expired - Lifetime CA2283280C (en) | 1997-08-13 | 1998-08-12 | Reovirus for the treatment of neoplasia |
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| EP (3) | EP1213023A1 (https=) |
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| NZ (1) | NZ337493A (https=) |
| PT (1) | PT1003534E (https=) |
| WO (1) | WO1999008692A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2013163727A1 (en) * | 2012-04-30 | 2013-11-07 | Oncolytics Biotech Inc. | Protecting modified viruses from neutralizing antibodies using the reovirus sigma 1 protein |
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| US6565831B1 (en) | 1999-02-24 | 2003-05-20 | Oncolytics Biotech Inc. | Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders |
| US6110461A (en) * | 1997-08-13 | 2000-08-29 | Oncolytics Biotech Inc. | Reovirus for the treatment of neoplasia |
| US6136307A (en) * | 1997-08-13 | 2000-10-24 | Oncolytics Biotech Inc. | Reovirus for the treatment of cellular proliferative disorders |
| US20030044384A1 (en) * | 1997-10-09 | 2003-03-06 | Pro-Virus, Inc. | Treatment of neoplasms with viruses |
| US7470426B1 (en) | 1997-10-09 | 2008-12-30 | Wellstat Biologics Corporation | Treatment of neoplasms with viruses |
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| AU2005201079C1 (en) * | 1999-04-15 | 2008-11-06 | Wellstat Biologics Corporation | Treatment of neoplasms with viruses |
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| US6896881B1 (en) * | 1999-09-24 | 2005-05-24 | Mayo Foundation For Medical Education And Research | Therapeutic methods and compositions using viruses of the recombinant paramyxoviridae family |
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1997
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1998
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- 1998-08-12 EP EP01130285A patent/EP1213023A1/en not_active Withdrawn
- 1998-08-12 PT PT98940002T patent/PT1003534E/pt unknown
- 1998-08-12 AU AU88471/98A patent/AU731810B2/en not_active Expired
- 1998-08-12 DE DE1003534T patent/DE1003534T1/de active Pending
- 1998-08-12 AT AT98940002T patent/ATE213948T1/de not_active IP Right Cessation
- 1998-08-12 DE DE69804106T patent/DE69804106T2/de not_active Expired - Lifetime
- 1998-08-12 ES ES98940002T patent/ES2157870T3/es not_active Expired - Lifetime
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- 1998-08-12 DK DK98940002T patent/DK1003534T3/da active
- 1998-08-12 JP JP51259099A patent/JP4291884B2/ja not_active Expired - Lifetime
- 1998-08-12 EP EP98940002A patent/EP1003534B1/en not_active Expired - Lifetime
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- 1998-08-12 WO PCT/CA1998/000774 patent/WO1999008692A1/en not_active Ceased
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2000
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2003
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2004
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2008
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013163727A1 (en) * | 2012-04-30 | 2013-11-07 | Oncolytics Biotech Inc. | Protecting modified viruses from neutralizing antibodies using the reovirus sigma 1 protein |
| WO2013163724A1 (en) * | 2012-04-30 | 2013-11-07 | Oncolytics Biotech Inc. | Protecting modified viruses from neutralizing antibodies using the reovirus sigma 1 protein |
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