CA2280518A1 - Hiv integrase inhibitors - Google Patents

Hiv integrase inhibitors Download PDF

Info

Publication number
CA2280518A1
CA2280518A1 CA002280518A CA2280518A CA2280518A1 CA 2280518 A1 CA2280518 A1 CA 2280518A1 CA 002280518 A CA002280518 A CA 002280518A CA 2280518 A CA2280518 A CA 2280518A CA 2280518 A1 CA2280518 A1 CA 2280518A1
Authority
CA
Canada
Prior art keywords
compound
aids
hiv
atcc
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002280518A
Other languages
English (en)
French (fr)
Inventor
Deborah L. Zink
Ana M. Teran
Russell B. Lingham
Ali Shafiee
Sheo Bux Singh
Keith C. Silverman
Fernando Pelaez
Gerald F. Bills
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9707492.6A external-priority patent/GB9707492D0/en
Application filed by Individual filed Critical Individual
Publication of CA2280518A1 publication Critical patent/CA2280518A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002280518A 1997-02-06 1998-02-03 Hiv integrase inhibitors Abandoned CA2280518A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US3690297P 1997-02-06 1997-02-06
US60/036,902 1997-02-06
GBGB9707492.6A GB9707492D0 (en) 1997-04-14 1997-04-14 HIV integrase inhibitors
GB9707492.6 1997-04-14
PCT/US1998/002292 WO1998034932A1 (en) 1997-02-06 1998-02-03 Hiv integrase inhibitors

Publications (1)

Publication Number Publication Date
CA2280518A1 true CA2280518A1 (en) 1998-08-13

Family

ID=26311374

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002280518A Abandoned CA2280518A1 (en) 1997-02-06 1998-02-03 Hiv integrase inhibitors

Country Status (4)

Country Link
EP (1) EP1023281A1 (de)
AU (1) AU6271098A (de)
CA (1) CA2280518A1 (de)
WO (1) WO1998034932A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1367784A (zh) * 1999-06-02 2002-09-04 盐野义制药株式会社 新的取代丙烯酮衍生物的制备方法
GB0200957D0 (en) * 2002-01-17 2002-03-06 Secr Defence Novel polymer and uses thereof
AU2004257645A1 (en) * 2003-07-07 2005-01-27 David H. Wagner Methods for predicting development of auto-immune diseases and treatment of same
US8283366B2 (en) 2010-01-22 2012-10-09 Ambrilia Biopharma, Inc. Derivatives of pyridoxine for inhibiting HIV integrase
CN113717145B (zh) * 2021-09-18 2023-05-26 中国热带农业科学院热带作物品种资源研究所 双萘并r-吡喃酮类化合物及其在抗植物炭疽菌中的应用

Also Published As

Publication number Publication date
WO1998034932A1 (en) 1998-08-13
AU6271098A (en) 1998-08-26
EP1023281A4 (de) 2000-08-02
EP1023281A1 (de) 2000-08-02

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Legal Events

Date Code Title Description
FZDE Discontinued