CA2274803C - Activateur du recepteur de nf-kappab, recepteur membre de la superfamille des recepteurs de tnf - Google Patents

Activateur du recepteur de nf-kappab, recepteur membre de la superfamille des recepteurs de tnf Download PDF

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Publication number
CA2274803C
CA2274803C CA2274803A CA2274803A CA2274803C CA 2274803 C CA2274803 C CA 2274803C CA 2274803 A CA2274803 A CA 2274803A CA 2274803 A CA2274803 A CA 2274803A CA 2274803 C CA2274803 C CA 2274803C
Authority
CA
Canada
Prior art keywords
rank
polypeptide
seq
amino acid
ser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2274803A
Other languages
English (en)
Other versions
CA2274803A1 (fr
Inventor
Dirk M. Anderson
Laurent J. Galibert
Eugene Maraskovsky
William C. Dougall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunex Corp
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Priority claimed from PCT/US1997/023866 external-priority patent/WO1998028424A2/fr
Publication of CA2274803A1 publication Critical patent/CA2274803A1/fr
Application granted granted Critical
Publication of CA2274803C publication Critical patent/CA2274803C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Abstract

Récepteurs isolés, ADNs codant ces récepteurs et compositions pharmaceutiques préparées à partir de ces récepteurs. On peut utiliser ces récepteurs isolés afin de réguler une réaction immune. Ces récepteurs sont également utiles pour rechercher leurs inhibiteurs par criblage.
CA2274803A 1996-12-23 1997-12-22 Activateur du recepteur de nf-kappab, recepteur membre de la superfamille des recepteurs de tnf Expired - Fee Related CA2274803C (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US5997896P 1996-12-23 1996-12-23
US60/059,978 1996-12-23
US81350997A 1997-03-07 1997-03-07
US08/813,509 1997-03-07
US6467197P 1997-10-14 1997-10-14
US60/064,671 1997-10-14
PCT/US1997/023866 WO1998028424A2 (fr) 1996-12-23 1997-12-22 Activateur du recepteur de nf-kappab, recepteur membre de la superfamille des recepteurs de tnf

Publications (2)

Publication Number Publication Date
CA2274803A1 CA2274803A1 (fr) 1998-07-02
CA2274803C true CA2274803C (fr) 2012-05-22

Family

ID=43981413

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2274803A Expired - Fee Related CA2274803C (fr) 1996-12-23 1997-12-22 Activateur du recepteur de nf-kappab, recepteur membre de la superfamille des recepteurs de tnf

Country Status (4)

Country Link
JP (1) JP2013005802A (fr)
CA (1) CA2274803C (fr)
IL (3) IL130491A (fr)
PT (1) PT946725E (fr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2274987C (fr) * 1996-12-23 2012-01-24 Immunex Corporation Ligand pour l'activateur des recepteurs du nf-kappa b, ligand membre de la superfamille de tnf

Also Published As

Publication number Publication date
IL215020A0 (fr) 2011-10-31
PT946725E (pt) 2011-04-20
IL130491A0 (en) 2000-06-01
CA2274803A1 (fr) 1998-07-02
IL215021A0 (en) 2011-10-31
IL130491A (en) 2011-10-31
JP2013005802A (ja) 2013-01-10

Similar Documents

Publication Publication Date Title
CA2274987C (fr) Ligand pour l'activateur des recepteurs du nf-kappa b, ligand membre de la superfamille de tnf
WO1998028426A9 (fr) Ligand pour l'activateur des recepteurs du nf-kappab, ligand membre de la superfamille de tnf
CA2274803C (fr) Activateur du recepteur de nf-kappab, recepteur membre de la superfamille des recepteurs de tnf
AU741504B2 (en) Receptor activator of NF-kappa B, receptor is member of TNF receptor superfamily

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20151222