CA2252706A1 - Polypeptide conjugates for transporting substances across cell membranes - Google Patents
Polypeptide conjugates for transporting substances across cell membranes Download PDFInfo
- Publication number
- CA2252706A1 CA2252706A1 CA002252706A CA2252706A CA2252706A1 CA 2252706 A1 CA2252706 A1 CA 2252706A1 CA 002252706 A CA002252706 A CA 002252706A CA 2252706 A CA2252706 A CA 2252706A CA 2252706 A1 CA2252706 A1 CA 2252706A1
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- polypeptide
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
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- A—HUMAN NECESSITIES
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
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- General Health & Medical Sciences (AREA)
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- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1634796P | 1996-05-01 | 1996-05-01 | |
| US2860996P | 1996-10-23 | 1996-10-23 | |
| US60/016,347 | 1996-10-23 | ||
| US60/028,609 | 1996-10-23 | ||
| PCT/US1997/007335 WO1997040854A2 (en) | 1996-05-01 | 1997-04-30 | Polypeptide conjugates for transporting substances across cell membranes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2252706A1 true CA2252706A1 (en) | 1997-11-06 |
Family
ID=26688485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002252706A Abandoned CA2252706A1 (en) | 1996-05-01 | 1997-04-30 | Polypeptide conjugates for transporting substances across cell membranes |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0966303A2 (OSRAM) |
| JP (1) | JP2000509394A (OSRAM) |
| AU (1) | AU729643B2 (OSRAM) |
| CA (1) | CA2252706A1 (OSRAM) |
| WO (1) | WO1997040854A2 (OSRAM) |
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| ATE291617T1 (de) * | 1997-01-24 | 2005-04-15 | Avi Biopharm Inc | Verfahren und konjugat zur behandlung von helicobacter pylori-infektionen |
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| WO1998052614A2 (en) | 1997-05-21 | 1998-11-26 | The Board Of Trustees Of The Leland Stanford Junior University | Composition and method for enhancing transport across biological membranes |
| US6958148B1 (en) | 1998-01-20 | 2005-10-25 | Pericor Science, Inc. | Linkage of agents to body tissue using microparticles and transglutaminase |
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| US20020064520A1 (en) * | 1999-08-19 | 2002-05-30 | Yanina Rozenberg | Targeted artificial gene delivery |
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| WO2001013957A2 (en) * | 1999-08-24 | 2001-03-01 | Cellgate, Inc. | Enhancing drug delivery across and into epithelial tissues using oligo arginine moieties |
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| ES2617692T3 (es) | 2000-07-21 | 2017-06-19 | Revance Therapeutics, Inc. | Sistemas de transporte de agentes biológicos de múltiples componentes |
| JP2004523480A (ja) * | 2000-08-22 | 2004-08-05 | ニュー リバー ファーマシューティカルズ， インコーポレイテッド | 活性作用物質送達系ならびに活性作用物質の保護および投与方法 |
| JP2006516948A (ja) * | 2000-11-14 | 2006-07-13 | ニュー リバー ファーマシューティカルズ インコーポレイテッド | 硫酸アバカビルを含有する新規な薬剤化合物および同化合物の製造ならびに使用方法 |
| AU2003217676B2 (en) * | 2002-02-22 | 2009-06-11 | Takeda Pharmaceutical Company Limited | Active agent delivery systems and methods for protecting and administering active agents |
| ATE512674T1 (de) | 2003-01-06 | 2011-07-15 | Angiochem Inc | Angiopep-1, verwandte verbindungen, und deren verwnedungen |
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| US9211248B2 (en) | 2004-03-03 | 2015-12-15 | Revance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
| AU2005327188C9 (en) | 2004-07-02 | 2011-09-22 | Avi Biopharma, Inc. | Antisense antibacterial method and compound |
| AU2006213686A1 (en) | 2005-02-09 | 2006-08-17 | Avi Bio Pharma, Inc. | Antisense composition and method for treating muscle atrophy |
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| EP1856139B1 (en) | 2005-03-03 | 2011-04-27 | Revance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of an oligopeptide |
| US8067571B2 (en) | 2005-07-13 | 2011-11-29 | Avi Biopharma, Inc. | Antibacterial antisense oligonucleotide and method |
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| US9365634B2 (en) | 2007-05-29 | 2016-06-14 | Angiochem Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
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| EP2143726A1 (en) * | 2008-07-11 | 2010-01-13 | Novosom AG | Nucleic acid comprising zwitterionic nucleotides |
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| CA2745524C (en) | 2008-12-05 | 2020-06-09 | Angiochem Inc. | Conjugates of neurotensin or neurotensin analogs and uses thereof |
| US8592386B2 (en) * | 2008-12-17 | 2013-11-26 | Sarepta Therapeutics, Inc. | Antisense compositions and methods for modulating contact hypersensitivity or contact dermatitis |
| AU2010239069B2 (en) | 2009-04-20 | 2015-05-14 | Angiochem Inc | Treatment of ovarian cancer using an anticancer agent conjugated to an Angiopep-2 analog |
| EP2437772B1 (en) | 2009-06-05 | 2017-12-06 | 13Therapeutics, Inc. | Immunoregulatory peptides and methods of use |
| WO2011000095A1 (en) | 2009-07-02 | 2011-01-06 | Angiochem Inc. | Multimeric peptide conjugates and uses thereof |
| CN107353317A (zh) | 2010-05-28 | 2017-11-17 | 萨勒普塔医疗公司 | 具有修饰的亚基间键和/或端基的寡核苷酸类似物 |
| US10017763B2 (en) | 2010-09-03 | 2018-07-10 | Sarepta Therapeutics, Inc. | dsRNA molecules comprising oligonucleotide analogs having modified intersubunit linkages and/or terminal groups |
| US8580748B2 (en) | 2011-04-06 | 2013-11-12 | 13Therapeutics, Inc. | Peptides for the treatment of hearing |
| US20130085139A1 (en) | 2011-10-04 | 2013-04-04 | Royal Holloway And Bedford New College | Oligomers |
| US9278987B2 (en) | 2011-11-18 | 2016-03-08 | Sarepta Therapeutics, Inc. | Functionally-modified oligonucleotides and subunits thereof |
| EA031110B1 (ru) | 2012-03-20 | 2018-11-30 | Сарепта Терапьютикс, Инк. | Конъюгаты бороновых кислот олигонуклеотидных аналогов |
| GB201210358D0 (en) * | 2012-06-12 | 2012-07-25 | Polytherics Ltd | Complexes |
| WO2014026283A1 (en) | 2012-08-14 | 2014-02-20 | Angiochem Inc. | Peptide-dendrimer conjugates and uses thereof |
| MA41795A (fr) | 2015-03-18 | 2018-01-23 | Sarepta Therapeutics Inc | Exclusion d'un exon induite par des composés antisens dans la myostatine |
| US11020417B2 (en) | 2015-06-04 | 2021-06-01 | Sarepta Therapeutics, Inc | Methods and compounds for treatment of lymphocyte-related diseases and conditions |
| EP3307326B9 (en) | 2015-06-15 | 2021-02-24 | Angiochem Inc. | Methods for the treatment of leptomeningeal carcinomatosis |
| WO2017062699A1 (en) * | 2015-10-07 | 2017-04-13 | Cormedix Inc. | Skin-penetrating formulation of taurolidine |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1541436A (en) * | 1976-02-02 | 1979-02-28 | Searle & Co | Immunological materials |
| GB9017024D0 (en) * | 1990-08-03 | 1990-09-19 | Erba Carlo Spa | New linker for bioactive agents |
| GB9026491D0 (en) * | 1990-12-05 | 1991-01-23 | Erba Carlo Spa | Anthracycline-conjugates |
| EP0932399B1 (en) * | 1996-03-12 | 2006-01-04 | PG-TXL Company, L.P. | Water soluble paclitaxel prodrugs |
-
1997
- 1997-04-30 JP JP9539221A patent/JP2000509394A/ja not_active Ceased
- 1997-04-30 WO PCT/US1997/007335 patent/WO1997040854A2/en not_active Ceased
- 1997-04-30 AU AU29298/97A patent/AU729643B2/en not_active Ceased
- 1997-04-30 EP EP97923513A patent/EP0966303A2/en not_active Withdrawn
- 1997-04-30 CA CA002252706A patent/CA2252706A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997040854A2 (en) | 1997-11-06 |
| EP0966303A2 (en) | 1999-12-29 |
| AU2929897A (en) | 1997-11-19 |
| WO1997040854A3 (en) | 1998-03-12 |
| JP2000509394A (ja) | 2000-07-25 |
| AU729643B2 (en) | 2001-02-08 |
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