CA2251558C - Complexe du facteur viii hautement purifie - Google Patents

Complexe du facteur viii hautement purifie Download PDF

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Publication number
CA2251558C
CA2251558C CA002251558A CA2251558A CA2251558C CA 2251558 C CA2251558 C CA 2251558C CA 002251558 A CA002251558 A CA 002251558A CA 2251558 A CA2251558 A CA 2251558A CA 2251558 C CA2251558 C CA 2251558C
Authority
CA
Canada
Prior art keywords
vwf
factor viii
preparation
complex
plasma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002251558A
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English (en)
Other versions
CA2251558A1 (fr
Inventor
Wolfgang Schonhofer
Johann Eibl
Alfred Weber
Yendra Linnau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oesterreichisches Institut fuer Haemoderivate
Original Assignee
Immuno AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT0066796A external-priority patent/AT403765B/de
Application filed by Immuno AG filed Critical Immuno AG
Publication of CA2251558A1 publication Critical patent/CA2251558A1/fr
Application granted granted Critical
Publication of CA2251558C publication Critical patent/CA2251558C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne un complexe hautement purifié ayant comme composants le factor VIII et le facteur de von Willebrand (vWF), présentant une activité spécifique d'au moins 70, de préférence de 100 à 300 E du facteur VIII/mg. L'invention concerne également une préparation pharmaceutique stable contenant ce complexe, ainsi qu'un procédé de production de ce complexe, fondé sur la chromatographie d'immunoaffinité.
CA002251558A 1996-04-12 1997-04-09 Complexe du facteur viii hautement purifie Expired - Fee Related CA2251558C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ATA667/96 1996-04-12
AT0066796A AT403765B (de) 1996-04-12 1996-04-12 Verfahren zur herstellung einer präparation enthaltend einen hochgereinigten komplex
PCT/AT1997/000069 WO1997039033A1 (fr) 1996-04-12 1997-04-09 Purification du complexe du facteur viii par chromatographie d'immunoaffinite

Publications (2)

Publication Number Publication Date
CA2251558A1 CA2251558A1 (fr) 1997-10-23
CA2251558C true CA2251558C (fr) 2005-11-22

Family

ID=35474793

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002251558A Expired - Fee Related CA2251558C (fr) 1996-04-12 1997-04-09 Complexe du facteur viii hautement purifie

Country Status (1)

Country Link
CA (1) CA2251558C (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT406867B (de) 1997-02-27 2000-10-25 Immuno Ag Verfahren zur gewinnung von hochreinem vwf oder faktor viii/vwf-komplex
AT406373B (de) 1997-02-27 2000-04-25 Immuno Ag Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie

Also Published As

Publication number Publication date
CA2251558A1 (fr) 1997-10-23

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