CA2251090C - Derives de phenylethanolaminotetralincarboxamide - Google Patents

Derives de phenylethanolaminotetralincarboxamide Download PDF

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Publication number
CA2251090C
CA2251090C CA002251090A CA2251090A CA2251090C CA 2251090 C CA2251090 C CA 2251090C CA 002251090 A CA002251090 A CA 002251090A CA 2251090 A CA2251090 A CA 2251090A CA 2251090 C CA2251090 C CA 2251090C
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Canada
Prior art keywords
carbon atom
configuration
amino group
pharmaceutically acceptable
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002251090A
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English (en)
Other versions
CA2251090A1 (fr
Inventor
Makio Kitazawa
Kosuke Okazaki
Tetsuro Tamai
Masaru Saito
Nobuyuki Tanaka
Hiroaki Kobayashi
Ken Kikuchi
Hideyuki Muranaka
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Kissei Pharmaceutical Co Ltd
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Kissei Pharmaceutical Co Ltd
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Publication date
Application filed by Kissei Pharmaceutical Co Ltd filed Critical Kissei Pharmaceutical Co Ltd
Priority claimed from PCT/JP1997/001159 external-priority patent/WO1997038970A1/fr
Publication of CA2251090A1 publication Critical patent/CA2251090A1/fr
Application granted granted Critical
Publication of CA2251090C publication Critical patent/CA2251090C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Dérivé de phényléthanolaminotétralincarboxamide représenté par la formule générale (I) et des sels pharmacologiquement acceptables de ceux-ci. Dans la formule (I), A représente alkylène inférieur; B représente amino, di(alkyle inférieur)amino ou amino alicyclique à 3 à 7 éléments qui peut porter oxygène sur le cycle; l'atome de carbone marqué d'un astérisque représente un atome de carbone à configuration R- ou S- ou un mélange de ces atomes; et l'atome de carbone marqué d'un (S) représente un atome de carbone à configuration S. Ces composés comprennent un récepteur adrénergique- beta 2 sélectif stimulant les effets tout en réduisant la charge du coeur, telle que la tachychardie, et sont utiles en tant qu'agents de prévention du risque d'avortement, d'accouchement prématuré, en tant qu'agents de bronchodilatation, de rémission et agent pour l'expulsion des calculs urinaires.
CA002251090A 1996-04-12 1997-04-04 Derives de phenylethanolaminotetralincarboxamide Expired - Fee Related CA2251090C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP12622596 1996-04-12
JP8/126225 1996-04-12
PCT/JP1997/001159 WO1997038970A1 (fr) 1996-04-12 1997-04-04 Derives de phenylethanolaminotetralincarboxamide

Publications (2)

Publication Number Publication Date
CA2251090A1 CA2251090A1 (fr) 1997-10-23
CA2251090C true CA2251090C (fr) 2006-02-21

Family

ID=35985384

Family Applications (1)

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CA002251090A Expired - Fee Related CA2251090C (fr) 1996-04-12 1997-04-04 Derives de phenylethanolaminotetralincarboxamide

Country Status (1)

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CA (1) CA2251090C (fr)

Also Published As

Publication number Publication date
CA2251090A1 (fr) 1997-10-23

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