CA2249348C - Preparation comprenant une combinaison de 5-methylisoxazol-4-acide carboxylique-(4-trifluoromethyl)-anilide et de n-(4-trifluoromethylphenyl)-2-cyano-3-acide hydroxycrotonique amide - Google Patents

Preparation comprenant une combinaison de 5-methylisoxazol-4-acide carboxylique-(4-trifluoromethyl)-anilide et de n-(4-trifluoromethylphenyl)-2-cyano-3-acide hydroxycrotonique amide Download PDF

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Publication number
CA2249348C
CA2249348C CA002249348A CA2249348A CA2249348C CA 2249348 C CA2249348 C CA 2249348C CA 002249348 A CA002249348 A CA 002249348A CA 2249348 A CA2249348 A CA 2249348A CA 2249348 C CA2249348 C CA 2249348C
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composition
component
compound
cancer
content
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Expired - Lifetime
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CA002249348A
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CA2249348A1 (fr
Inventor
Robert Bartlett
Johann Then
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Sanofi Aventis Deutschland GmbH
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Sanofi Aventis Deutschland GmbH
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Priority claimed from DE19610955A external-priority patent/DE19610955A1/de
Application filed by Sanofi Aventis Deutschland GmbH filed Critical Sanofi Aventis Deutschland GmbH
Publication of CA2249348A1 publication Critical patent/CA2249348A1/fr
Application granted granted Critical
Publication of CA2249348C publication Critical patent/CA2249348C/fr
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CA002249348A 1996-03-20 1997-03-07 Preparation comprenant une combinaison de 5-methylisoxazol-4-acide carboxylique-(4-trifluoromethyl)-anilide et de n-(4-trifluoromethylphenyl)-2-cyano-3-acide hydroxycrotonique amide Expired - Lifetime CA2249348C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19610955A DE19610955A1 (de) 1996-03-20 1996-03-20 Kombinationspräparat, enthaltend 5-Methylisoxazol-4-carbonsäure-(4-trifluormethyl)- anilid und N-(4-Trifluormethylphenyl)-2-cyan-3- hydroxycrotonsäureamid
DE19610955.8 1996-03-20
PCT/EP1997/001167 WO1997034600A1 (fr) 1996-03-20 1997-03-07 Preparation comprenant une combinaison de 5-methylisoxazol-4-acide carboxylique-(4-trifluoromethyl)-anilide et de n-(4-trifluoromethylphenyl)-2-cyano-3-acide hydroxycrotonique amide

Publications (2)

Publication Number Publication Date
CA2249348A1 CA2249348A1 (fr) 1997-09-25
CA2249348C true CA2249348C (fr) 2006-10-03

Family

ID=37101799

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002249348A Expired - Lifetime CA2249348C (fr) 1996-03-20 1997-03-07 Preparation comprenant une combinaison de 5-methylisoxazol-4-acide carboxylique-(4-trifluoromethyl)-anilide et de n-(4-trifluoromethylphenyl)-2-cyano-3-acide hydroxycrotonique amide

Country Status (1)

Country Link
CA (1) CA2249348C (fr)

Also Published As

Publication number Publication date
CA2249348A1 (fr) 1997-09-25

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