CA2240682C - Procede de preparation d'une fraction d'acide hyaluronique a faible indice de polydispersite - Google Patents

Procede de preparation d'une fraction d'acide hyaluronique a faible indice de polydispersite Download PDF

Info

Publication number
CA2240682C
CA2240682C CA002240682A CA2240682A CA2240682C CA 2240682 C CA2240682 C CA 2240682C CA 002240682 A CA002240682 A CA 002240682A CA 2240682 A CA2240682 A CA 2240682A CA 2240682 C CA2240682 C CA 2240682C
Authority
CA
Canada
Prior art keywords
hyaluronic acid
molecular weight
process according
average molecular
acid fraction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002240682A
Other languages
English (en)
Other versions
CA2240682A1 (fr
Inventor
Lanfranco Callegaro
Davide Renier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidia Farmaceutici SpA
Original Assignee
Fidia Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT95PD000244A external-priority patent/IT1282219B1/it
Application filed by Fidia Farmaceutici SpA filed Critical Fidia Farmaceutici SpA
Publication of CA2240682A1 publication Critical patent/CA2240682A1/fr
Application granted granted Critical
Publication of CA2240682C publication Critical patent/CA2240682C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Procédé de préparation d'une fraction d'acide hyaluronique présentant un poids moléculaire moyen compris entre 5 000 et 300 000, et un indice de polydispersité inférieur à 1,7, consistant à traiter l'acide hyaluronique de poids moléculaire élevé de départ avec de l'hypochlorite de sodium et simultanément avec des ultrasons.
CA002240682A 1995-12-20 1996-12-19 Procede de preparation d'une fraction d'acide hyaluronique a faible indice de polydispersite Expired - Fee Related CA2240682C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITPD95A000244 1995-12-20
IT95PD000244A IT1282219B1 (it) 1995-12-20 1995-12-20 Processo chimico fisico combinato per la preparazione di frazioni di acido ialuronico a basso peso molecolare caratterizzate da bassa
PCT/EP1996/005701 WO1997022629A1 (fr) 1995-12-20 1996-12-19 Procede de preparation d'une fraction d'acide hyaluronique a faible indice de polydispersite

Publications (2)

Publication Number Publication Date
CA2240682A1 CA2240682A1 (fr) 1997-06-26
CA2240682C true CA2240682C (fr) 2006-02-14

Family

ID=35892336

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002240682A Expired - Fee Related CA2240682C (fr) 1995-12-20 1996-12-19 Procede de preparation d'une fraction d'acide hyaluronique a faible indice de polydispersite

Country Status (1)

Country Link
CA (1) CA2240682C (fr)

Also Published As

Publication number Publication date
CA2240682A1 (fr) 1997-06-26

Similar Documents

Publication Publication Date Title
US6020484A (en) Process for preparing a hyaluronic acid fraction having a low polydispersion index
AU2001291815B8 (en) Percarboxylated polysaccharides, and a process for their preparation
DK173818B1 (da) Heparinderivat
JP4278716B2 (ja) Ｎ−硫酸化ヒアルロン酸化合物、その誘導体および製造方法
EP1144459B2 (fr) Acides hyaluroniques reticules et leur utilisation medicale
CA2556942C (fr) Esters d'acide hyaluronique comprenant de la rheine, procede de preparation associe et compositions comprenant lesdits esters
AU2001291815A1 (en) Percarboxylated polysaccharides, and a process for their preparation
JP2011174079A (ja) ヒアルロン酸アミドおよびそれらの誘導体、並びにそれらの製造法
JP2009545637A (ja) 分岐ヒアルロン酸及びその製造方法
KR20100092494A (ko) 산성 다당체의 부티르산-포름산 에스테르 혼합물, 및 그의 제조 및 피부 화장료로서의 용도
CA2240682C (fr) Procede de preparation d'une fraction d'acide hyaluronique a faible indice de polydispersite
IL141230A (en) Hyaluronic acid derivatives obtained from hyaluronic acid fraction having a low polydispersion index and pharmaceutical compositions and healthcare products containing them
WO2008090583A1 (fr) Dérivés phosphatés de polysaccharides et leurs utilisations
EP3922268B1 (fr) Nouveaux dérivés obtenus à partir d'acide hyaluronique et de carnosine
WO2018079812A1 (fr) Composition de gel, et procédé de fabrication de celle-ci
JP2024509534A (ja) ポリマーをベースとする植込み型又は注入型生成物及びそれらの調製方法
MXPA06008467A (en) Esters of hyaluronic acid with rhein, process for their preparation and compositions comprising the same
MXPA01004712A (en) Cross-linked hyaluronic acids and medical uses thereof

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20121219