CA2239733A1 - Gene de predisposition au cancer du sein lie au chromosome 13 - Google Patents

Gene de predisposition au cancer du sein lie au chromosome 13

Info

Publication number
CA2239733A1
CA2239733A1 CA002239733A CA2239733A CA2239733A1 CA 2239733 A1 CA2239733 A1 CA 2239733A1 CA 002239733 A CA002239733 A CA 002239733A CA 2239733 A CA2239733 A CA 2239733A CA 2239733 A1 CA2239733 A1 CA 2239733A1
Authority
CA
Canada
Prior art keywords
breast cancer
relates
gene
human
brca2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002239733A
Other languages
English (en)
Other versions
CA2239733C (fr
Inventor
Sean V. Tavtigian
Alexander Kamb
Jacques Simard
Fergus Couch
Johanna M. Rommens
Barbara L. Weber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Endorecherche Inc
HSC Research and Development LP
Myriad Genetics Inc
University of Pennsylvania Penn
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27541925&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2239733(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/639,501 external-priority patent/US5837492A/en
Application filed by Individual filed Critical Individual
Publication of CA2239733A1 publication Critical patent/CA2239733A1/fr
Application granted granted Critical
Publication of CA2239733C publication Critical patent/CA2239733C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/828—Cancer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002239733A 1995-12-18 1996-12-17 Gene de predisposition au cancer du sein lie au chromosome 13 Expired - Fee Related CA2239733C (fr)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US57377995A 1995-12-18 1995-12-18
US08/573,779 1995-12-18
US57535995A 1995-12-20 1995-12-20
US08/575,359 1995-12-20
US57655995A 1995-12-21 1995-12-21
US08/576,559 1995-12-21
US58539196A 1996-01-11 1996-01-11
US08/585,391 1996-01-11
US08/639,501 1996-04-29
US08/639,501 US5837492A (en) 1995-12-18 1996-04-29 Chromosome 13-linked breast cancer susceptibility gene
PCT/US1996/019598 WO1997022689A1 (fr) 1995-12-18 1996-12-17 Gene de predisposition au cancer du sein lie au chromosome 13

Publications (2)

Publication Number Publication Date
CA2239733A1 true CA2239733A1 (fr) 1997-06-26
CA2239733C CA2239733C (fr) 2001-04-03

Family

ID=27541925

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002239733A Expired - Fee Related CA2239733C (fr) 1995-12-18 1996-12-17 Gene de predisposition au cancer du sein lie au chromosome 13

Country Status (11)

Country Link
US (2) US6124104A (fr)
EP (1) EP0785216B2 (fr)
JP (1) JP3455228B2 (fr)
AT (1) ATE230759T1 (fr)
AU (1) AU1461597A (fr)
CA (1) CA2239733C (fr)
DE (1) DE69625678T3 (fr)
IL (1) IL124620A0 (fr)
NO (1) NO982785L (fr)
NZ (1) NZ326525A (fr)
WO (1) WO1997022689A1 (fr)

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US6617104B2 (en) 1996-12-03 2003-09-09 Michael R. Swift Predisposition to breast cancer by mutations at the ataxia-telangiectasia genetic locus
GB9708221D0 (en) * 1997-04-23 1997-06-11 Cancer Res Campaign Tech Substances and uses thereof
EP2275574B1 (fr) * 1997-08-15 2015-06-03 Gene Logic Inc. Codage d'haplotypes de séquence du gène BRCA2 humain
US20090269814A1 (en) * 1998-05-22 2009-10-29 Murphy Patricia D Method of Analyzing a BRCA2 Gene in a Human Subject
US6492109B1 (en) 1997-09-23 2002-12-10 Gene Logic, Inc. Susceptibility mutation 6495delGC of BRCA2
US6051379A (en) * 1997-09-23 2000-04-18 Oncormed, Inc. Cancer susceptibility mutations of BRCA2
US6686163B2 (en) 1998-05-06 2004-02-03 Gene Logic Inc. Coding sequence haplotype of the human BRCA1 gene
US20030180789A1 (en) * 1998-12-30 2003-09-25 Dale Roderic M.K. Arrays with modified oligonucleotide and polynucleotide compositions
US6087112A (en) * 1998-12-30 2000-07-11 Oligos Etc. Inc. Arrays with modified oligonucleotide and polynucleotide compositions
US7148016B1 (en) * 1999-01-14 2006-12-12 Ca*Tx Inc. Immunoassays to detect diseases or disease susceptibility traits
AUPQ421699A0 (en) * 1999-11-24 1999-12-16 University Of Western Australia, The Tumour suppressor factor
US20050013803A1 (en) * 2000-07-07 2005-01-20 Benjamin Thomas L. Diagnosing and treating cancer cells using mutant viruses
US20030157481A1 (en) * 2001-12-10 2003-08-21 Benjamin Thomas L. Diagnosing and treating cancer cells using T-HR mutants and their targets
US20030188326A1 (en) * 2000-11-03 2003-10-02 Dana Farber Cancer Institute Methods and compositions for the diagnosis of cancer susceptibilities and defective DNA repair mechanisms and treatment thereof
EP2298878A3 (fr) 2000-11-03 2011-11-16 Dana Farber Cancer Institute Procédés et compositions pour le diagnostic de cancer
US6816789B2 (en) * 2001-04-19 2004-11-09 Varian, Inc. Method and system for analyzing chromatograms
ATE353976T1 (de) * 2001-06-05 2007-03-15 Auckland Uniservices Ltd Verfahren und zusammensetzungen zur beurteilung der lungenfunktion und von lungenerkrankungen
AU2002359398A1 (en) * 2001-11-16 2003-06-10 Exelixis, Inc. Nucleic acids and polypeptides of invertebrate brca2 and methods of use
US20030139466A1 (en) * 2001-11-29 2003-07-24 Peritt David L. Methods for pretreating a subject with extracorporeal photopheresis
AU2006244683A1 (en) * 2005-05-10 2006-11-16 Synergenz Bioscience Limited Methods and compositions for assessment of pulmonary function and disorders
EP1888777A4 (fr) * 2005-05-19 2008-11-26 Synergenz Bioscience Ltd Procédés et compositions d'évaluation des fonctions et troubles pulmonaires
EP1888776A4 (fr) * 2005-05-19 2009-07-29 Synergenz Bioscience Ltd Méthodes et compositions pour évaluation de la fonction et de troubles pulmonaires
AU2006248189A1 (en) * 2005-05-20 2006-11-23 Synergenz Bioscience Limited Methods of analysis of polymorphisms and uses thereof
US8768629B2 (en) 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
CN101449162B (zh) 2006-05-18 2013-07-31 分子压型学会股份有限公司 确定针对病状的个性化医疗介入的系统和方法
WO2007148997A1 (fr) * 2006-06-22 2007-12-27 Pomorska Akademia Medyczna Détermination de la prédisposition au cancer par l'identification de combinaisons génotypiques de variants spécifiques des gènes cyp1b1, brca2 et chek2
EP2949763A3 (fr) 2006-08-11 2016-03-09 Johns Hopkins University Séquences de codage de consensus des cancers du sein humains
US7993835B1 (en) 2007-05-11 2011-08-09 Myriad Genetics, Inc. BRCA2 mutations and use thereof
EP2347009A4 (fr) * 2008-10-14 2012-05-30 Caris Mpi Inc Cibles géniques et protéiques exprimées par des gènes représentant des profils de biomarqueurs et des jeux de signatures par type de tumeurs
GB2463401B (en) 2008-11-12 2014-01-29 Caris Life Sciences Luxembourg Holdings S A R L Characterizing prostate disorders by analysis of microvesicles
WO2011057125A2 (fr) * 2009-11-05 2011-05-12 Myriad Genetics, Inc. Compositions et procédés pour la détermination de la susceptibilité à un cancer
AU2011223789A1 (en) 2010-03-01 2012-09-20 Caris Life Sciences Switzerland Holdings Gmbh Biomarkers for theranostics
CA2795776A1 (fr) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Biomarqueurs circulants pour une maladie
US20130018700A1 (en) * 2011-07-14 2013-01-17 International Business Machines Corporation Optimizing product portfolios under customer choice
US20140222512A1 (en) * 2013-02-01 2014-08-07 Goodsnitch, Inc. Receiving, tracking and analyzing business intelligence data
US20140343982A1 (en) * 2013-05-14 2014-11-20 Landmark Graphics Corporation Methods and systems related to workflow mentoring
AU2015236054B2 (en) * 2014-03-25 2019-11-21 Five3 Genomics, Llc Systems and methods for RNA analysis in functional confirmation of cancer mutations
US10133996B2 (en) * 2014-04-22 2018-11-20 International Business Machines Corporation Object lifecycle analysis tool
CN104962613B (zh) * 2015-06-02 2019-12-03 南京医科大学 一种用于乳腺癌辅助诊断的突变基因及其应用

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GB2307477B (en) * 1995-11-23 1997-10-22 Cancer Res Campaign Tech Materials and methods relating to the identification and sequencing of the BRCA2 cancer susceptibility gene and uses thereof
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US6376176B1 (en) † 1999-09-13 2002-04-23 Cedars-Sinai Medical Center Methods of using a major histocompatibility complex class III haplotype to diagnose Crohn's disease
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Also Published As

Publication number Publication date
CA2239733C (fr) 2001-04-03
NO982785D0 (no) 1998-06-17
WO1997022689A1 (fr) 1997-06-26
IL124620A0 (en) 1998-12-06
JP3455228B2 (ja) 2003-10-14
NZ326525A (en) 1999-11-29
DE69625678T3 (de) 2006-11-09
AU1461597A (en) 1997-07-14
EP0785216B2 (fr) 2006-06-07
DE69625678T2 (de) 2003-11-06
EP0785216B1 (fr) 2003-01-08
NO982785L (no) 1998-08-17
US6033857A (en) 2000-03-07
ATE230759T1 (de) 2003-01-15
DE69625678D1 (de) 2003-02-13
US6124104A (en) 2000-09-26
EP0785216A1 (fr) 1997-07-23

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Effective date: 20161219