CA2234723A1 - Production de peptides d : methodes et compositions - Google Patents

Production de peptides d : methodes et compositions Download PDF

Info

Publication number
CA2234723A1
CA2234723A1 CA 2234723 CA2234723A CA2234723A1 CA 2234723 A1 CA2234723 A1 CA 2234723A1 CA 2234723 CA2234723 CA 2234723 CA 2234723 A CA2234723 A CA 2234723A CA 2234723 A1 CA2234723 A1 CA 2234723A1
Authority
CA
Canada
Prior art keywords
peptide
ligand
antibody
amino acid
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2234723
Other languages
English (en)
Inventor
Barry Robson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gryphon Therapeutics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2234723A1 publication Critical patent/CA2234723A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention porte sur des procédés de production et d'utilisation d'anticorps D et de peptides D. Lesdits anticorps et peptides sont des analogues de ligands ou de récepteurs pouvant se fixer spécifiquement aux peptides L, aux peptides contenant à la fois des L-aminoacides et des D-aminoacides de peptides chiraux et non chiraux non naturels, et à des composés chiraux et non chiraux non peptidiques. Lesdits peptides et anticorps résistent à la protéolyse dans l'intestin et dans le corps et sont moins immunogènes que leurs contreparties, les anticorps L et les peptides L. L'invention porte également sur leur procédé de fabrication.
CA 2234723 1995-10-10 1996-10-10 Production de peptides d : methodes et compositions Abandoned CA2234723A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US550895P 1995-10-10 1995-10-10
US1443396P 1996-03-28 1996-03-28
US60/014,433 1996-03-28
US60/005,508 1996-03-28

Publications (1)

Publication Number Publication Date
CA2234723A1 true CA2234723A1 (fr) 1997-04-17

Family

ID=26674440

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2234723 Abandoned CA2234723A1 (fr) 1995-10-10 1996-10-10 Production de peptides d : methodes et compositions

Country Status (5)

Country Link
EP (1) EP0862447A1 (fr)
JP (1) JP2000500431A (fr)
AU (1) AU7442296A (fr)
CA (1) CA2234723A1 (fr)
WO (1) WO1997013522A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9722131D0 (en) * 1997-10-20 1997-12-17 Medical Res Council Method
US6599506B1 (en) * 1999-04-21 2003-07-29 The University Of Kansas D-form polypeptide that inhibits the interaction between LFA-1 and ICAM-1
CA2491611A1 (fr) 2002-07-03 2004-01-15 Bio Science International, Inc. Peptides comprenant des aminoacides d aromatiques et leurs methodes d'utilisation
KR101323846B1 (ko) * 2011-04-08 2013-10-31 광주과학기술원 타겟 친화도가 유지되고 안정성이 개선된 ｄ－앱타이드
WO2013172954A1 (fr) 2012-05-17 2013-11-21 Ra Pharmaceuticals, Inc Inhibiteurs de peptides et de peptidomimétiques

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5248611A (en) * 1987-05-28 1993-09-28 Scripps Clinic And Research Foundation Stereoisomer separation method using antibody combing site-containing molecules
US5079152A (en) * 1987-05-28 1992-01-07 Scripps Clinic And Research Foundation Antibody combining sites that exhibit stereoselective synthase activity, and methods using the same

Also Published As

Publication number Publication date
WO1997013522A1 (fr) 1997-04-17
JP2000500431A (ja) 2000-01-18
AU7442296A (en) 1997-04-30
EP0862447A1 (fr) 1998-09-09

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Legal Events

Date Code Title Description
FZDE Dead