CA2233296A1 - Compose presentant une homologie de sequence avec une phospholipase a2 associee a une lipoproteine (lp-pla2) ou acetyle hydrolase du facteur d'activation des plaquettes - Google Patents

Compose presentant une homologie de sequence avec une phospholipase a2 associee a une lipoproteine (lp-pla2) ou acetyle hydrolase du facteur d'activation des plaquettes Download PDF

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Publication number
CA2233296A1
CA2233296A1 CA002233296A CA2233296A CA2233296A1 CA 2233296 A1 CA2233296 A1 CA 2233296A1 CA 002233296 A CA002233296 A CA 002233296A CA 2233296 A CA2233296 A CA 2233296A CA 2233296 A1 CA2233296 A1 CA 2233296A1
Authority
CA
Canada
Prior art keywords
polypeptide
polynucleotide
dna
sequence
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002233296A
Other languages
English (en)
Inventor
Christopher Donald Southan
Simon Quentyn John Rice
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA002233296A priority Critical patent/CA2233296A1/fr
Publication of CA2233296A1 publication Critical patent/CA2233296A1/fr
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

On décrit des polynucléotides codant le polypeptide de SEQ ID N0 1, lequel présente plus ou moins 40 % d'homologie avec la phospholipase A2 associée à une lipoprotéine (Lp-PLA2) ou acétyle hydrolase du facteur d'activation des plaquettes (PAF).
CA002233296A 1995-09-29 1995-09-29 Compose presentant une homologie de sequence avec une phospholipase a2 associee a une lipoproteine (lp-pla2) ou acetyle hydrolase du facteur d'activation des plaquettes Abandoned CA2233296A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002233296A CA2233296A1 (fr) 1995-09-29 1995-09-29 Compose presentant une homologie de sequence avec une phospholipase a2 associee a une lipoproteine (lp-pla2) ou acetyle hydrolase du facteur d'activation des plaquettes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002233296A CA2233296A1 (fr) 1995-09-29 1995-09-29 Compose presentant une homologie de sequence avec une phospholipase a2 associee a une lipoproteine (lp-pla2) ou acetyle hydrolase du facteur d'activation des plaquettes

Publications (1)

Publication Number Publication Date
CA2233296A1 true CA2233296A1 (fr) 1997-04-10

Family

ID=4162251

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002233296A Abandoned CA2233296A1 (fr) 1995-09-29 1995-09-29 Compose presentant une homologie de sequence avec une phospholipase a2 associee a une lipoproteine (lp-pla2) ou acetyle hydrolase du facteur d'activation des plaquettes

Country Status (1)

Country Link
CA (1) CA2233296A1 (fr)

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Legal Events

Date Code Title Description
FZDE Discontinued