CA2231385A1 - A high throughput assay using fusion proteins - Google Patents

A high throughput assay using fusion proteins Download PDF

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Publication number
CA2231385A1
CA2231385A1 CA002231385A CA2231385A CA2231385A1 CA 2231385 A1 CA2231385 A1 CA 2231385A1 CA 002231385 A CA002231385 A CA 002231385A CA 2231385 A CA2231385 A CA 2231385A CA 2231385 A1 CA2231385 A1 CA 2231385A1
Authority
CA
Canada
Prior art keywords
binding
fusion protein
protein
screening
leu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002231385A
Other languages
English (en)
French (fr)
Inventor
Scott P. Salowe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603486.3A external-priority patent/GB9603486D0/en
Application filed by Individual filed Critical Individual
Publication of CA2231385A1 publication Critical patent/CA2231385A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9493—Immunosupressants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
CA002231385A 1995-09-15 1996-09-11 A high throughput assay using fusion proteins Abandoned CA2231385A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US382495P 1995-09-15 1995-09-15
US60/003,824 1995-09-15
GB9603486.3 1996-02-20
GBGB9603486.3A GB9603486D0 (en) 1996-02-20 1996-02-20 A high throughputassay using fusion proteins
PCT/US1996/014563 WO1997010502A1 (en) 1995-09-15 1996-09-11 A high throughput assay using fusion proteins

Publications (1)

Publication Number Publication Date
CA2231385A1 true CA2231385A1 (en) 1997-03-20

Family

ID=26308762

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002231385A Abandoned CA2231385A1 (en) 1995-09-15 1996-09-11 A high throughput assay using fusion proteins

Country Status (4)

Country Link
EP (1) EP0855029A4 (ja)
JP (1) JP2000501171A (ja)
CA (1) CA2231385A1 (ja)
WO (1) WO1997010502A1 (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187757B1 (en) 1995-06-07 2001-02-13 Ariad Pharmaceuticals, Inc. Regulation of biological events using novel compounds
WO1998041866A1 (en) * 1997-03-14 1998-09-24 Merck & Co., Inc. A high throughput assay using fusion proteins
EP1144655A2 (en) * 1998-10-19 2001-10-17 Ariad Gene Therapeutics, Inc. Regulated expression using conditional er retention domains
US7067526B1 (en) 1999-08-24 2006-06-27 Ariad Gene Therapeutics, Inc. 28-epirapalogs
ATE522603T1 (de) 2001-06-22 2011-09-15 Hoffmann La Roche Löslicher komplex, der retrovirale oberflächen- glykoproteine und fkpa oder slyd enthält
WO2004060346A2 (en) 2002-12-30 2004-07-22 Angiotech International Ag Drug delivery from rapid gelling polymer composition
EP1892530A1 (en) * 2006-08-25 2008-02-27 Boehringer Ingelheim Pharma GmbH & Co. KG Method for determining transport activity of a transport protein
US8921642B2 (en) 2008-01-11 2014-12-30 Massachusetts Eye And Ear Infirmary Conditional-stop dimerizable caspase transgenic animals
CA2905229C (en) 2013-06-11 2023-10-10 Clontech Laboratories, Inc. Protein enriched microvesicles and methods of making and using the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154734B1 (en) * 1984-03-15 1990-08-29 Immunex Corporation Immediate ligand detection assay, a test kit and its formation

Also Published As

Publication number Publication date
EP0855029A4 (en) 2000-03-08
WO1997010502A1 (en) 1997-03-20
JP2000501171A (ja) 2000-02-02
EP0855029A1 (en) 1998-07-29

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Legal Events

Date Code Title Description
FZDE Discontinued