CA2221978A1 - Utilisation d'un sel d'hydrate d'hydrazone de 6-carboxy-3-methylbenzothiazolone en depistage colorimetrique de peroxyde d'hydrogene - Google Patents

Utilisation d'un sel d'hydrate d'hydrazone de 6-carboxy-3-methylbenzothiazolone en depistage colorimetrique de peroxyde d'hydrogene Download PDF

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Publication number
CA2221978A1
CA2221978A1 CA 2221978 CA2221978A CA2221978A1 CA 2221978 A1 CA2221978 A1 CA 2221978A1 CA 2221978 CA2221978 CA 2221978 CA 2221978 A CA2221978 A CA 2221978A CA 2221978 A1 CA2221978 A1 CA 2221978A1
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CA
Canada
Prior art keywords
hydrogen
group
alkyl
heteroaryl
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2221978
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English (en)
Inventor
Yuri A. Nikolyukin
David J. Gibboni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Actimed Laboratories Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2221978A1 publication Critical patent/CA2221978A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/16—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing hetero atoms
    • C09B23/162—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing hetero atoms only nitrogen atoms
    • C09B23/166—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing hetero atoms only nitrogen atoms containing two or more nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B27/00—Preparations in which the azo group is formed in any way other than by diazotising and coupling, e.g. oxidation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
    • C12Q2326/32—3-Methyl-2-benzothiazolinone hydrazone hydrochloride hydrate, i.e. MBTH

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Abstract

Les sels solubles dans l'eau de composés d'hydrazone réagissent rapidement avec des composés d'aniline en présence d'une peroxydase et de peroxyde d'hydrogène, produisant une couleur qui peut être mesurée par spectrophotométrie ou visuellement lorsqu'ils sont incorporés à une solution ou à un dispositif de mesure d'analytes. Ces sels d'hydrazone solubles dans l'eau sont utiles pour dépister le peroxyde d'hydrogène ou un analyte qui réagit en produisant du peroxyde d'hydrogène dans un liquide aqueux. A cet effet, on met physiquement en contact un échantillon liquide avec une composition colorante constituée d'un sel soluble dans l'eau d'un composé d'hydrazone et d'un composé d'aniline substitué ou non, en présence d'une substance à activité peroxydante, afin de produire un pigment coloré, et on détecte ensuite le pigment qui se forme en présence de peroxyde d'hydrogène ou d'un analyte qui réagit en produisant du peroxyde d'hydrogène.
CA 2221978 1995-05-25 1996-05-24 Utilisation d'un sel d'hydrate d'hydrazone de 6-carboxy-3-methylbenzothiazolone en depistage colorimetrique de peroxyde d'hydrogene Abandoned CA2221978A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45078095A 1995-05-25 1995-05-25
US08/450,780 1995-05-25

Publications (1)

Publication Number Publication Date
CA2221978A1 true CA2221978A1 (fr) 1996-11-28

Family

ID=23789457

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2221978 Abandoned CA2221978A1 (fr) 1995-05-25 1996-05-24 Utilisation d'un sel d'hydrate d'hydrazone de 6-carboxy-3-methylbenzothiazolone en depistage colorimetrique de peroxyde d'hydrogene

Country Status (4)

Country Link
EP (1) EP0840798A1 (fr)
AU (1) AU5878896A (fr)
CA (1) CA2221978A1 (fr)
WO (1) WO1996037629A1 (fr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3124594A1 (de) * 1981-06-23 1983-01-05 Boehringer Mannheim Gmbh, 6800 Mannheim Mittel und verfahren zum nachweis von wasserstoffperoxid
US4492714A (en) * 1983-02-25 1985-01-08 Beatrice Foods Co. Non-protein, high stability fat emulsion composition and method of production
DE3446637A1 (de) * 1984-12-20 1986-07-03 Boehringer Mannheim Gmbh, 6800 Mannheim Mittel zur verbesserung des nachweises h(pfeil abwaerts)2(pfeil abwaerts)0(pfeil abwaerts)2(pfeil abwaerts)-liefernder oxidase-reaktionen und seine verwendung
DE3517273A1 (de) * 1985-05-14 1986-11-20 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von azoverbindungen
EP0555045B1 (fr) * 1992-02-03 1997-10-08 Lifescan, Inc. Colorant oxidatif copulant amélioré pour l'analyse quantitative des analytes

Also Published As

Publication number Publication date
AU5878896A (en) 1996-12-11
EP0840798A1 (fr) 1998-05-13
WO1996037629A1 (fr) 1996-11-28

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