CA2220349C - Coatings for production of hyperpolarized noble gases - Google Patents

Coatings for production of hyperpolarized noble gases Download PDF

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Publication number
CA2220349C
CA2220349C CA002220349A CA2220349A CA2220349C CA 2220349 C CA2220349 C CA 2220349C CA 002220349 A CA002220349 A CA 002220349A CA 2220349 A CA2220349 A CA 2220349A CA 2220349 C CA2220349 C CA 2220349C
Authority
CA
Canada
Prior art keywords
modified
polymer
noble gas
deuterated
container
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002220349A
Other languages
English (en)
French (fr)
Other versions
CA2220349A1 (en
Inventor
Bastiaan Driehuys
William Happer
Gordon D. Cates, Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Princeton University
Original Assignee
Princeton University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Princeton University filed Critical Princeton University
Publication of CA2220349A1 publication Critical patent/CA2220349A1/en
Application granted granted Critical
Publication of CA2220349C publication Critical patent/CA2220349C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/282—Means specially adapted for hyperpolarisation or for hyperpolarised contrast agents, e.g. for the generation of hyperpolarised gases using optical pumping cells, for storing hyperpolarised contrast agents or for the determination of the polarisation of a hyperpolarised contrast agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A61K49/1815—Suspensions, emulsions, colloids, dispersions compo-inhalant, e.g. breath tests
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/14—Linings or internal coatings
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B23/00—Noble gases; Compounds thereof
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
    • F17C—VESSELS FOR CONTAINING OR STORING COMPRESSED, LIQUEFIED OR SOLIDIFIED GASES; FIXED-CAPACITY GAS-HOLDERS; FILLING VESSELS WITH, OR DISCHARGING FROM VESSELS, COMPRESSED, LIQUEFIED, OR SOLIDIFIED GASES
    • F17C1/00—Pressure vessels, e.g. gas cylinder, gas tank, replaceable cartridge
    • F17C1/16—Pressure vessels, e.g. gas cylinder, gas tank, replaceable cartridge constructed of plastics materials
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
    • F17C—VESSELS FOR CONTAINING OR STORING COMPRESSED, LIQUEFIED OR SOLIDIFIED GASES; FIXED-CAPACITY GAS-HOLDERS; FILLING VESSELS WITH, OR DISCHARGING FROM VESSELS, COMPRESSED, LIQUEFIED, OR SOLIDIFIED GASES
    • F17C2203/00—Vessel construction, in particular walls or details thereof
    • F17C2203/06—Materials for walls or layers thereof; Properties or structures of walls or their materials
    • F17C2203/0602—Wall structures; Special features thereof
    • F17C2203/0607—Coatings
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
    • F17C—VESSELS FOR CONTAINING OR STORING COMPRESSED, LIQUEFIED OR SOLIDIFIED GASES; FIXED-CAPACITY GAS-HOLDERS; FILLING VESSELS WITH, OR DISCHARGING FROM VESSELS, COMPRESSED, LIQUEFIED, OR SOLIDIFIED GASES
    • F17C2221/00—Handled fluid, in particular type of fluid
    • F17C2221/07—Hyperpolarised gases
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
    • F17C—VESSELS FOR CONTAINING OR STORING COMPRESSED, LIQUEFIED OR SOLIDIFIED GASES; FIXED-CAPACITY GAS-HOLDERS; FILLING VESSELS WITH, OR DISCHARGING FROM VESSELS, COMPRESSED, LIQUEFIED, OR SOLIDIFIED GASES
    • F17C2270/00—Applications
    • F17C2270/05—Applications for industrial use
    • F17C2270/0527—Superconductors
    • F17C2270/0536—Magnetic resonance imaging
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
    • Y10T428/131—Glass, ceramic, or sintered, fused, fired, or calcined metal oxide or metal carbide containing [e.g., porcelain, brick, cement, etc.]
    • Y10T428/1317—Multilayer [continuous layer]
    • Y10T428/1321—Polymer or resin containing [i.e., natural or synthetic]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31551—Of polyamidoester [polyurethane, polyisocyanate, polycarbamate, etc.]
    • Y10T428/31609—Particulate metal or metal compound-containing
    • Y10T428/31612—As silicone, silane or siloxane

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Dispersion Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Details Of Rigid Or Semi-Rigid Containers (AREA)
  • Physical Vapour Deposition (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Inorganic Insulating Materials (AREA)
  • Chemically Coating (AREA)
  • Paints Or Removers (AREA)
  • Containers Having Bodies Formed In One Piece (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
CA002220349A 1995-06-07 1996-06-07 Coatings for production of hyperpolarized noble gases Expired - Fee Related CA2220349C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/478,276 US5612103A (en) 1995-06-07 1995-06-07 Coatings for production of hyperpolarized noble gases
US08/478,276 1995-06-07
PCT/US1996/009402 WO1996039912A1 (en) 1995-06-07 1996-06-07 Coatings for production of hyperpolarized noble gases

Publications (2)

Publication Number Publication Date
CA2220349A1 CA2220349A1 (en) 1996-12-19
CA2220349C true CA2220349C (en) 2002-01-22

Family

ID=23899257

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002220349A Expired - Fee Related CA2220349C (en) 1995-06-07 1996-06-07 Coatings for production of hyperpolarized noble gases

Country Status (12)

Country Link
US (1) US5612103A (enExample)
EP (1) EP0837641B1 (enExample)
JP (2) JP3971799B2 (enExample)
CN (1) CN1149165C (enExample)
AT (1) ATE378366T1 (enExample)
BR (1) BR9609064A (enExample)
CA (1) CA2220349C (enExample)
DE (1) DE69637324T2 (enExample)
DK (1) DK0837641T3 (enExample)
MX (1) MX9709600A (enExample)
NO (1) NO324090B1 (enExample)
WO (1) WO1996039912A1 (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5642625A (en) * 1996-03-29 1997-07-01 The Trustees Of Princeton University High volume hyperpolarizer for spin-polarized noble gas
NZ502784A (en) * 1997-08-13 2002-06-28 Univ Princeton Sol-gel coated polarization vessels
US6318092B1 (en) 1997-08-18 2001-11-20 The Trustees Of Princeton University Alkali metal hybrid spin-exchange optical pumping
PL340503A1 (en) 1997-11-14 2001-02-12 Norbert Weiler Apparatus for administering fluids
US6079213A (en) * 1997-12-12 2000-06-27 Magnetic Imaging Technologies Incorporated Methods of collecting, thawing, and extending the useful life of polarized gases and associated accumulators and heating jackets
CN1284158A (zh) * 1997-12-12 2001-02-14 磁成象技术公司 极化气体储蓄器和加热夹套及相关的气体收集和熔化方法以及极化气体产品
US6128918A (en) * 1998-07-30 2000-10-10 Medi-Physics, Inc. Containers for hyperpolarized gases and associated methods
NZ508720A (en) * 1998-06-17 2003-08-29 Medi Physics Inc Resilient containers for hyperpolarized gases
US6423387B1 (en) 1998-06-17 2002-07-23 Medi-Physics, Inc. Resilient containers for hyperpolarized gases and associated methods
NZ508719A (en) * 1998-06-17 2002-10-25 Medi Physics Inc Hyperpolarized gas transport device with at least one gas chamber and a electromagnet providing a magnetic holding field
US6237363B1 (en) 1998-09-30 2001-05-29 Medi-Physics, Inc. Hyperpolarized noble gas extraction methods masking methods and associated transport containers
US6286319B1 (en) 1998-09-30 2001-09-11 Medi-Physics, Inc. Meted hyperpolarized noble gas dispensing methods and associated devices
US6523356B2 (en) 1998-09-30 2003-02-25 Medi-Physics, Inc. Meted hyperpolarized noble gas dispensing methods and associated devices
US6125654A (en) * 1998-10-16 2000-10-03 Syracuse University Bulk production and usage of hyperpolarized 129 Xenon
US6284222B1 (en) 1998-11-03 2001-09-04 Medi--Physics, Inc. Hyperpolarized helium-3 microbubble gas entrapment methods
US6566875B1 (en) 1999-02-23 2003-05-20 Medi-Physics, Inc. Portable hyperpolarized gas monitoring systems, computer program products, and related methods using NMR and/or MRI during transport
DE19927788C2 (de) * 1999-06-18 2003-03-06 Forschungszentrum Juelich Gmbh Polarisator für die Polarisation eines Edelgases
US6295834B1 (en) 1999-06-30 2001-10-02 Medi-Physics, Inc. NMR polarization monitoring coils, hyperpolarizers with same, and methods for determining the polarization level of accumulated hyperpolarized noble gases during production
GB9920758D0 (en) 1999-09-03 1999-11-03 Nycomed Amersham Plc Improved container composition for diagnostic agents
DE10000675C2 (de) 2000-01-11 2001-11-15 Otten Ernst Wilhelm Lineardurchführung, Vorrichtung und Verfahren zur hochproduktiven Erzeugung von hoch kernspinpolarisiertem Helium-3 Gas
US7035518B2 (en) * 2001-04-13 2006-04-25 Hitachi Cable, Ltd. Polymer waveguides and process for producing the same
US6830818B2 (en) * 2001-04-13 2004-12-14 Hitachi Cable, Ltd. Polymer material and polymer film
CA2509801A1 (en) 2003-01-17 2004-08-05 Medi-Physics Inc. Method of producing optically pumped hyperpolarized gas
US7275540B2 (en) * 2003-04-22 2007-10-02 Medi-Physics, Inc. MRI/NMR-compatible, tidal volume control and measurement systems, methods, and devices for respiratory and hyperpolarized gas delivery
WO2009143368A2 (en) * 2008-05-23 2009-11-26 University Of Utah Non-cryogenic storage cell for hyperpolarized 129xe
US9874622B2 (en) 2013-09-27 2018-01-23 General Electric Company Hyperpolarized media transport vessel
CN106456808B (zh) 2014-02-21 2019-11-19 杜克大学 具有纳米簇抑制、检测和/或过滤的超偏振稀有气体生产系统及相关的方法和装置
CN104651905B (zh) * 2015-01-28 2017-11-07 永保纳米科技(深圳)有限公司 一种阳极铝匀染缓染助剂及其操作液，和阳极铝匀染缓染处理工艺
CN112833870B (zh) * 2020-12-30 2023-01-06 中国人民解放军国防科技大学 核磁共振陀螺中抑制碱金属原子极化磁场影响的有效方法
GB2612838A (en) * 2021-11-15 2023-05-17 Hyperspin Ltd Apparatus for pumping hyperpolarised gas and method of handling hyperpolarised gas
CN114644322B (zh) * 2022-04-15 2024-02-06 宁波诺丁汉大学 超极化稀有气体生产设备
WO2025151298A1 (en) 2024-01-10 2025-07-17 Polarean, Inc. Hyperpolarizers with a load-lock chamber for alkali metal

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US3657363A (en) * 1967-09-15 1972-04-18 Us Army Process for the deuteration of the hydroxyl position of organic alcohols
US3642851A (en) * 1968-12-27 1972-02-15 Union Carbide Corp Preparation of linear halosiloxanes and compounds derived therefrom
US3646090A (en) * 1969-05-29 1972-02-29 Union Carbide Corp Process for preparing linear chlorine terminated siloxane compounds
US3966781A (en) * 1970-12-17 1976-06-29 Merck Sharp & Dohme (I.A.) Corporation Deuteration of functional group-containing hydrocarbons
US3989705A (en) * 1974-04-01 1976-11-02 Canadian Patents And Development Limited Processes for the deuteration and/or tritiation of organic substrates by hydrogen substitution
US4586511A (en) * 1983-03-04 1986-05-06 Children's Hospital Medical Center Methods and compositions for detecting and imaging a gas in an animal by nuclear magnetic resonance
US4882384A (en) * 1988-02-01 1989-11-21 Shell Oil Company Modified block copolymers
US4914160A (en) * 1988-06-23 1990-04-03 Hormoz Azizian Deuteration of unsaturated polymers and copolymers
JPH0731545A (ja) * 1993-07-22 1995-02-03 Toho Kasei Kk フッ素樹脂塗膜を有する加熱容器
JP2938727B2 (ja) * 1993-09-14 1999-08-25 信越化学工業株式会社 メチルジメトキシシランの保存方法

Also Published As

Publication number Publication date
DE69637324D1 (de) 2007-12-27
CN1192128A (zh) 1998-09-02
JP3971799B2 (ja) 2007-09-05
AU695121B2 (en) 1998-08-06
CN1149165C (zh) 2004-05-12
EP0837641A1 (en) 1998-04-29
BR9609064A (pt) 1999-09-21
JPH11508354A (ja) 1999-07-21
MX9709600A (es) 1998-10-31
WO1996039912A1 (en) 1996-12-19
DE69637324T2 (de) 2008-09-18
AU6098396A (en) 1996-12-30
DK0837641T3 (da) 2008-03-25
EP0837641A4 (en) 2002-07-17
ATE378366T1 (de) 2007-11-15
EP0837641B1 (en) 2007-11-14
JP2007292739A (ja) 2007-11-08
US5612103A (en) 1997-03-18
NO975725L (no) 1998-02-05
CA2220349A1 (en) 1996-12-19
NO975725D0 (no) 1997-12-05
JP4584278B2 (ja) 2010-11-17
NO324090B1 (no) 2007-08-13

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Legal Events

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EEER Examination request
MKLA Lapsed

Effective date: 20130607