CA2216139C - Virus de la laryngotracheite infectieuse recombine et ses utilisations - Google Patents

Virus de la laryngotracheite infectieuse recombine et ses utilisations Download PDF

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Publication number
CA2216139C
CA2216139C CA2216139A CA2216139A CA2216139C CA 2216139 C CA2216139 C CA 2216139C CA 2216139 A CA2216139 A CA 2216139A CA 2216139 A CA2216139 A CA 2216139A CA 2216139 C CA2216139 C CA 2216139C
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Canada
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ser
ala
leu
thr
arg
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CA2216139A
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English (en)
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CA2216139A1 (fr
Inventor
Martha A. Wild
Mark D. Cochran
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MSD International Holdings GmbH
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MSD International Holdings GmbH
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Publication of CA2216139A1 publication Critical patent/CA2216139A1/fr
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Publication of CA2216139C publication Critical patent/CA2216139C/fr
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Expired - Fee Related legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne un virus de laryngotrachéite infectieuse recombinée atténué comprenant le génome viral de la laryngotrachéite infectieuse, lequel contient une déletion dans le gène de la glycoprotéine gG. Ce virus atténué est utile en tant que vaccin contre le virus de la laryngotrachéite infectieuse. L'invention concerne également un virus de laryngotrachéite infectieuse recombiné atténué comprenant le génome viral de laryngotrachéite infectieuse, lequel contient une déletion dans le gène US2, le gène de type UL47, le gène ORF4 ou le gène de la glycoprotéine G60. En outre, l'invention concerne un procédé permettant de distinguer les poulets ou autres volailes vaccinés par un virus de laryngotrachéite infectieuse recombiné, lequel ne produit pas de glycoprotéine gG, de ceux contaminés par le virus de laryngotrachéite infectieuse naturel.
CA2216139A 1995-03-23 1996-03-21 Virus de la laryngotracheite infectieuse recombine et ses utilisations Expired - Fee Related CA2216139C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41012195A 1995-03-23 1995-03-23
US46819095A 1995-06-06 1995-06-06
US08/468,190 1995-06-06
US08/410,121 1995-06-06
PCT/US1996/003916 WO1996029396A1 (fr) 1995-03-23 1996-03-21 Virus de la laryngotracheite infectieuse recombine et ses utilisations

Publications (2)

Publication Number Publication Date
CA2216139A1 CA2216139A1 (fr) 1996-09-26
CA2216139C true CA2216139C (fr) 2013-01-08

Family

ID=27020873

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2216139A Expired - Fee Related CA2216139C (fr) 1995-03-23 1996-03-21 Virus de la laryngotracheite infectieuse recombine et ses utilisations

Country Status (4)

Country Link
EP (1) EP0822980A4 (fr)
JP (1) JP3964458B2 (fr)
CA (1) CA2216139C (fr)
WO (1) WO1996029396A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8821441D0 (en) 1988-09-13 1988-10-12 Animal Health Inst Viral vectors
FR2750866B1 (fr) * 1996-06-27 1998-11-27 Rhone Merieux Vaccin vivant recombinant aviaire, utilisant comme vecteur le virus de la laryngotracheite infectieuse aviaire
FR2757061B1 (fr) * 1996-12-16 1999-03-26 Rhone Merieux Vaccin vivant recombinant aviaire, utilisant comme vecteur le virus de la laryngotracheite infectieuse aviaire
JP4549188B2 (ja) 2002-09-18 2010-09-22 アメリカ合衆国 組換えヒト2型パラインフルエンザウイルス(HPIV2)のcDNAからの回収(recovery)、並びにPIVおよび他のヒト病原体に対する免疫応答を誘発する免疫原性組成物における、そしてベクターとしての組換えHPIV2の使用
WO2013057236A1 (fr) 2011-10-21 2013-04-25 Intervet International B.V. Produits de recombinaison d'un virus non pathogène de la maladie de marek qui codent des antigènes du virus infectieux de la laryngotrachéite et du virus de la maladie de newcastle
CN103874508A (zh) 2011-10-21 2014-06-18 英特维特国际股份有限公司 提供多价免疫的重组非致病性mdv载体
WO2018112051A1 (fr) * 2016-12-14 2018-06-21 Merial, Inc. Vecteurs hvt recombinants exprimant de multiples antigènes de pathogènes aviaires, et vaccins les contenant
CN109609468B (zh) * 2018-12-10 2020-06-30 畜科生物工程有限公司 一种六基因缺失的猪伪狂犬病毒、猪伪狂犬病疫苗以及制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3339854B2 (ja) * 1988-09-13 2002-10-28 メリアル ウイルスワクチン
US5436005A (en) * 1989-08-01 1995-07-25 Arthur Webster Pty. Ltd. Low virulence infectiouns laryngotracheitis (ILT) virus for vaccinating birds
EP0473210B1 (fr) * 1990-07-30 1994-04-13 Akzo Nobel N.V. Virus recombinant de la maladie de Marek
US6087127A (en) * 1990-08-24 2000-07-11 Board Of Trustees Operating Michigan State University Marek's disease herpesvirus DNA segment encoding glycoproteins, gD, gI and gE
WO1992003554A1 (fr) * 1990-08-24 1992-03-05 Arthur Webster Pty. Ltd. Vaccin contre le virus de la laryngotracheite infectieuse
CA2172387A1 (fr) * 1993-09-24 1995-03-30 Martha A. Wild Virus recombinant de la laryngotracheite infectieuse aviaire; applications

Also Published As

Publication number Publication date
WO1996029396A1 (fr) 1996-09-26
EP0822980A4 (fr) 2000-04-26
AU721451B2 (en) 2000-07-06
EP0822980A1 (fr) 1998-02-11
CA2216139A1 (fr) 1996-09-26
JPH11503009A (ja) 1999-03-23
AU5369096A (en) 1996-10-08
JP3964458B2 (ja) 2007-08-22

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