CA2212466C - Diaza-18-crown-6-ethers chromo-ionophores, specifiques pour le calcium - Google Patents

Diaza-18-crown-6-ethers chromo-ionophores, specifiques pour le calcium Download PDF

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Publication number
CA2212466C
CA2212466C CA002212466A CA2212466A CA2212466C CA 2212466 C CA2212466 C CA 2212466C CA 002212466 A CA002212466 A CA 002212466A CA 2212466 A CA2212466 A CA 2212466A CA 2212466 C CA2212466 C CA 2212466C
Authority
CA
Canada
Prior art keywords
alkyl
nitro
aryl
hydrogen
trifluoromethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002212466A
Other languages
English (en)
Other versions
CA2212466A1 (fr
Inventor
Wayne Woodrow Ii Weber
Calvin Roman Messing
Margaret Elizabeth Logan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Clinical Diagnostics Inc
Original Assignee
Ortho Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Clinical Diagnostics Inc filed Critical Ortho Clinical Diagnostics Inc
Publication of CA2212466A1 publication Critical patent/CA2212466A1/fr
Application granted granted Critical
Publication of CA2212466C publication Critical patent/CA2212466C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Preparations (AREA)
  • Inorganic Insulating Materials (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CA002212466A 1996-08-15 1997-08-06 Diaza-18-crown-6-ethers chromo-ionophores, specifiques pour le calcium Expired - Fee Related CA2212466C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/698,316 1996-08-15
US08/698,316 US5747345A (en) 1996-08-15 1996-08-15 Calcium specific diaza-18-crown-6-ether chromoionophores

Publications (2)

Publication Number Publication Date
CA2212466A1 CA2212466A1 (fr) 1998-02-15
CA2212466C true CA2212466C (fr) 2006-03-21

Family

ID=24804748

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002212466A Expired - Fee Related CA2212466C (fr) 1996-08-15 1997-08-06 Diaza-18-crown-6-ethers chromo-ionophores, specifiques pour le calcium

Country Status (10)

Country Link
US (1) US5747345A (fr)
EP (1) EP0826677B1 (fr)
JP (1) JP4361617B2 (fr)
AT (1) ATE207472T1 (fr)
CA (1) CA2212466C (fr)
DE (1) DE69707610T2 (fr)
DK (1) DK0826677T3 (fr)
ES (1) ES2163714T3 (fr)
PT (1) PT826677E (fr)
SI (1) SI0826677T1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6997963B2 (en) 2002-06-28 2006-02-14 L'oreal Use of a chromoionophore and/or fluoroionophore for dyeing human keratin fibres, dyeing compositions and methods
FR2841468B1 (fr) * 2002-06-28 2004-09-10 Oreal Utilisation pour la teinture des fibres keratiniques humaines d'un chromoionophore et/ou un fluoroionophore, compositions et procedes de teinture
US20040191567A1 (en) * 2002-09-03 2004-09-30 Caballero Gabriel Joseph Light emitting molecules and organic light emitting devices including light emitting molecules
US20040108509A1 (en) * 2002-09-03 2004-06-10 Caballero Gabriel Joseph Light emitting molecules and organic light emitting devices including light emitting molecules
US7393598B2 (en) * 2004-03-10 2008-07-01 Hcf Partners, L.P. Light emitting molecules and organic light emitting devices including light emitting molecules
WO2005097209A1 (fr) * 2004-03-10 2005-10-20 Coled Technologies, Inc. Molecules d'emission de lumiere et dispositifs d'emission de lumiere organiques contenant lesdites molecules
US11554182B2 (en) 2017-03-30 2023-01-17 Cornell University Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer
US11708283B2 (en) * 2018-06-01 2023-07-25 Cornell University Metal-chelating compositions and their use in methods of removing or inhibiting barium scale

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2842862A1 (de) * 1978-10-02 1980-04-10 Boehringer Mannheim Gmbh Verfahren zur bestimmung von ionen, polaren und/oder lipophilen substanzen in fluessigkeiten
US4649123A (en) * 1983-05-12 1987-03-10 Miles Laboratories, Inc. Ion test means having a hydrophilic carrier matrix
US4597903A (en) * 1984-08-21 1986-07-01 University Of Maryland Process for the direct preparation of N,N-disubstituted derivatives for 4,13-diaza-18-crown-6
US4603209A (en) * 1984-09-07 1986-07-29 The Regents Of The University Of California Fluorescent indicator dyes for calcium ions
EP0254202B1 (fr) * 1986-07-15 1991-09-18 Fuji Photo Film Co., Ltd. Méthode de production d'un dispositif d'analyse multi-couche intégrant
US4795712A (en) * 1987-04-10 1989-01-03 Eastman Kodak Company Calcium complexing dyes and their use in analytical compositions, elements and methods
CA2002917C (fr) * 1988-11-14 1998-01-06 Akwasi Minta Colorants fluorescents pour la detection de cations de metaux alcalins
US5405975A (en) * 1993-03-29 1995-04-11 Molecular Probes, Inc. Fluorescent ion-selective diaryldiaza crown ether conjugates
CA2031109C (fr) * 1990-07-27 1992-01-28 Susan J. Danielson Analogues de ligand pour des immunodosages derives de produits d'oxydation d'un acide dicarboxylique
US5245021A (en) * 1991-05-28 1993-09-14 Eastman Kodak Company 14-crown-4-ether derivatives
DE69324855T2 (de) * 1992-07-17 1999-11-04 Johnson & Johnson Clinical Diagnostics, Inc. Trockenes, analytisches Element und Methode zur kolorimetrischen Bestimmung von Lithiumionen
US5310888A (en) * 1992-10-22 1994-05-10 Miles Inc. Arylazo chromoionophores
CA2125832A1 (fr) * 1993-09-23 1995-03-24 Eddy Chapoteau Composition reactive et methode de dosage du lithium

Also Published As

Publication number Publication date
US5747345A (en) 1998-05-05
ES2163714T3 (es) 2002-02-01
EP0826677A1 (fr) 1998-03-04
CA2212466A1 (fr) 1998-02-15
JPH10130249A (ja) 1998-05-19
ATE207472T1 (de) 2001-11-15
JP4361617B2 (ja) 2009-11-11
DK0826677T3 (da) 2001-11-19
DE69707610D1 (de) 2001-11-29
EP0826677B1 (fr) 2001-10-24
PT826677E (pt) 2002-02-28
DE69707610T2 (de) 2002-05-08
SI0826677T1 (en) 2002-06-30

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