CA2205420A1 - Substance mk7634, process for production thereof, and anthelminthic containing said substance - Google Patents

Substance mk7634, process for production thereof, and anthelminthic containing said substance

Info

Publication number
CA2205420A1
CA2205420A1 CA002205420A CA2205420A CA2205420A1 CA 2205420 A1 CA2205420 A1 CA 2205420A1 CA 002205420 A CA002205420 A CA 002205420A CA 2205420 A CA2205420 A CA 2205420A CA 2205420 A1 CA2205420 A1 CA 2205420A1
Authority
CA
Canada
Prior art keywords
substance
active ingredient
anthelminthic
production
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002205420A
Other languages
French (fr)
Other versions
CA2205420C (en
Inventor
Mina Kanda
Noriko Chiba
Shigenori Kumazawa
Masayuki Takagi
Kenzo Harimaya
Tadaaki Okada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Nihon Nohyaku Co Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from PCT/JP1995/002387 external-priority patent/WO1996016070A1/en
Publication of CA2205420A1 publication Critical patent/CA2205420A1/en
Application granted granted Critical
Publication of CA2205420C publication Critical patent/CA2205420C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/02Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungal isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

An imperfect fungus such as a microorganism belonging to the genus Curvularia in a culture medium containing nutrients utilizable for normal microorganisms and isolating MK7634 substance of a molecular formula: C8H15N3O4 from the culture by, for example, solvent extraction, ion exchange resin technique or gel filtration chromatography. The MK7634 substance can be used as an active ingredient of drugs.
In particular, the MK7634 substance is a novel anthelmintic substance and expected to be used as an active ingredient of anthelmintics.
CA002205420A 1994-11-24 1995-11-22 Substance mk7634, process for production thereof, and anthelminthic containing said substance Expired - Fee Related CA2205420C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP6-290057 1994-11-24
JP29005794 1994-11-24
PCT/JP1995/002387 WO1996016070A1 (en) 1994-11-24 1995-11-22 Substance mk7634, process for production thereof, and anthelminthic containing said substance

Publications (2)

Publication Number Publication Date
CA2205420A1 true CA2205420A1 (en) 1996-05-30
CA2205420C CA2205420C (en) 2007-05-22

Family

ID=38156699

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002205420A Expired - Fee Related CA2205420C (en) 1994-11-24 1995-11-22 Substance mk7634, process for production thereof, and anthelminthic containing said substance

Country Status (1)

Country Link
CA (1) CA2205420C (en)

Also Published As

Publication number Publication date
CA2205420C (en) 2007-05-22

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed
MKLA Lapsed

Effective date: 20121122