CA2203565A1 - Synthesis of peptide nucleic acids (pnas) and analogues via submonomer approach - Google Patents

Synthesis of peptide nucleic acids (pnas) and analogues via submonomer approach

Info

Publication number
CA2203565A1
CA2203565A1 CA002203565A CA2203565A CA2203565A1 CA 2203565 A1 CA2203565 A1 CA 2203565A1 CA 002203565 A CA002203565 A CA 002203565A CA 2203565 A CA2203565 A CA 2203565A CA 2203565 A1 CA2203565 A1 CA 2203565A1
Authority
CA
Canada
Prior art keywords
agent
nucleobase
compound
submonomer
amino group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002203565A
Other languages
English (en)
French (fr)
Inventor
Ronald N. Zuckermann
Thomas Horn
Lutz S. Richter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2203565A1 publication Critical patent/CA2203565A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C07K14/003—Peptide-nucleic acids (PNAs)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CA002203565A 1994-11-14 1995-11-13 Synthesis of peptide nucleic acids (pnas) and analogues via submonomer approach Abandoned CA2203565A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34007394A 1994-11-14 1994-11-14
US08/340,073 1994-11-14

Publications (1)

Publication Number Publication Date
CA2203565A1 true CA2203565A1 (en) 1996-05-23

Family

ID=23331753

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002203565A Abandoned CA2203565A1 (en) 1994-11-14 1995-11-13 Synthesis of peptide nucleic acids (pnas) and analogues via submonomer approach

Country Status (5)

Country Link
EP (1) EP0792283A1 (de)
JP (1) JPH10509947A (de)
AU (1) AU4159396A (de)
CA (1) CA2203565A1 (de)
WO (1) WO1996015143A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59810914D1 (de) * 1997-05-14 2004-04-08 Morphochem Ag Verfahren zur herstellung von polymeren, die nucleobasen als seitengruppen aufweisen
JP2002520008A (ja) 1998-07-09 2002-07-09 バイオセプト インコーポレイテッド Ｄｎａ配列ハイブリッド形成を最適化するための改良されたペプチド核酸汎用ライブラリーの使用法
WO2024081849A1 (en) * 2022-10-13 2024-04-18 Carnegie Mellon University Post-synthetic modification of polynucleotides via acylation reagents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5539082A (en) * 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
DK51092D0 (da) * 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
US6228982B1 (en) * 1992-05-22 2001-05-08 Benget Norden Double-stranded peptide nucleic acids
DE4331011A1 (de) * 1993-09-13 1995-03-16 Bayer Ag Nukleinsäuren-bindende Oligomere mit C-Verzweigung für Therapie und Diagnostik

Also Published As

Publication number Publication date
JPH10509947A (ja) 1998-09-29
AU4159396A (en) 1996-06-06
WO1996015143A1 (en) 1996-05-23
EP0792283A1 (de) 1997-09-03

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Legal Events

Date Code Title Description
FZDE Dead