CA2194010A1 - Pulsatile delivery systems of biologically active agents using electro voltage pulsing for controlling membrane permeability - Google Patents

Pulsatile delivery systems of biologically active agents using electro voltage pulsing for controlling membrane permeability

Info

Publication number
CA2194010A1
CA2194010A1 CA 2194010 CA2194010A CA2194010A1 CA 2194010 A1 CA2194010 A1 CA 2194010A1 CA 2194010 CA2194010 CA 2194010 CA 2194010 A CA2194010 A CA 2194010A CA 2194010 A1 CA2194010 A1 CA 2194010A1
Authority
CA
Canada
Prior art keywords
agent
drug
tissue
substance
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2194010
Other languages
English (en)
French (fr)
Inventor
Ooi Wong
Tung-Fen Chen
Russell O. Potts
Durairaj Bommi Bommannan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cygnus Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2194010A1 publication Critical patent/CA2194010A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
CA 2194010 1994-06-24 1995-06-23 Pulsatile delivery systems of biologically active agents using electro voltage pulsing for controlling membrane permeability Abandoned CA2194010A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26530694A 1994-06-24 1994-06-24
US08/265,306 1994-06-24

Publications (1)

Publication Number Publication Date
CA2194010A1 true CA2194010A1 (en) 1996-01-04

Family

ID=23009917

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2194010 Abandoned CA2194010A1 (en) 1994-06-24 1995-06-23 Pulsatile delivery systems of biologically active agents using electro voltage pulsing for controlling membrane permeability

Country Status (5)

Country Link
EP (1) EP0766579A1 (ja)
JP (1) JPH10511008A (ja)
AU (1) AU2947795A (ja)
CA (1) CA2194010A1 (ja)
WO (1) WO1996000111A1 (ja)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6009345A (en) * 1992-08-17 1999-12-28 Genetronics, Inc. Method and apparatus for a combination of electroporation and iontophoresis for the delivery of drugs and genes
ATE365026T1 (de) * 1996-12-31 2007-07-15 Altea Therapeutics Corp Mikroporation von gewebe zur verabreichung von bioaktiven substanzen
AU8444698A (en) 1997-06-30 1999-01-25 Centre National De La Recherche Scientifique Improved method for transferring nucleic acid into multicelled eukaryo tic organism cells and combination therefor
ATE275423T1 (de) 1997-06-30 2004-09-15 Aventis Pharma Sa Verabreichung der nukleinsäure in den quergestreiften muskel
EP0952869A1 (en) * 1997-09-08 1999-11-03 Vyteris, Inc. Iontophoretic delivery of buprenorphine
DE69806794T2 (de) * 1997-11-04 2003-03-13 Genetronics Inc Kombinierte elektroporation-und iontophoresevorrichtung zur medikament-und genverabreichung
TW368420B (en) * 1997-11-04 1999-09-01 Genetronics Inc Apparatus and method for transdermal molecular delivery by applying sufficient amplitude of electric field to induce migration of molecules through pores in the stratum corneum
US6778853B1 (en) 1997-12-17 2004-08-17 University Of South Florida Electroporation device
US6192270B1 (en) * 1998-08-14 2001-02-20 Genetronics, Inc. Apparatus and method for the delivery of drugs and genes into tissue
US6148232A (en) * 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
AU765788B2 (en) * 1999-02-10 2003-10-02 Gmp Drug Delivery, Inc. Iontophoresis, electroporation and combination patches for local drug delivery
US7089053B1 (en) 1999-10-14 2006-08-08 Pola Chemical Industries Inc Compositions for drug administration by electroporation
JP4566496B2 (ja) * 1999-12-15 2010-10-20 ユニヴァーシティ オブ サウス フロリダ 電気穿孔素子及び電気穿孔方法
AU2002365542A1 (en) * 2001-11-27 2003-06-10 Cellectricon Ab A method for combined parallel agent delivery and electroporation for cell structures and use thereof
WO2004036202A1 (en) 2002-10-16 2004-04-29 Cellectricon Ab Nanoelectrodes and nanotips for recording transmembrane currents in a plurality of cells
AU2004228038A1 (en) * 2003-04-02 2004-10-21 Advancis Pharmaceutical Corporation Pulsatile transdermally administered antigens and adjuvants
US20060036209A1 (en) * 2003-11-13 2006-02-16 Janardhanan Subramony System and method for transdermal delivery
AU2005224182B2 (en) * 2004-03-19 2008-04-17 Mcneil Ab Means for transdermal administration of nicotine
EP2205967B1 (en) 2007-10-17 2013-05-01 Syneron Medical Ltd. Dissolution rate verification

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE143279T1 (de) * 1991-12-03 1996-10-15 Alza Corp Iontophoretische verbreichungsvorrichtung und versorgungsnetz dafür
JPH0670987A (ja) * 1992-08-28 1994-03-15 Katsuro Tachibana 薬物投与・体液採取ユニット及び装置

Also Published As

Publication number Publication date
AU2947795A (en) 1996-01-19
WO1996000111A1 (en) 1996-01-04
EP0766579A1 (en) 1997-04-09
JPH10511008A (ja) 1998-10-27

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Legal Events

Date Code Title Description
FZDE Dead