AU2947795A - Pulsatile delivery systems of biologically active agents using electro voltage pulsing for controlling membrane permeability - Google Patents

Pulsatile delivery systems of biologically active agents using electro voltage pulsing for controlling membrane permeability

Info

Publication number
AU2947795A
AU2947795A AU29477/95A AU2947795A AU2947795A AU 2947795 A AU2947795 A AU 2947795A AU 29477/95 A AU29477/95 A AU 29477/95A AU 2947795 A AU2947795 A AU 2947795A AU 2947795 A AU2947795 A AU 2947795A
Authority
AU
Australia
Prior art keywords
biologically active
active agents
delivery systems
membrane permeability
controlling membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU29477/95A
Other languages
English (en)
Inventor
Durairaj Bommi Bommannan
Tung-Fen Chen
Russell O Potts
Ooi Wong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cygnus Inc
Original Assignee
Cygnus Therapeutic Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cygnus Therapeutic Systems filed Critical Cygnus Therapeutic Systems
Publication of AU2947795A publication Critical patent/AU2947795A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
AU29477/95A 1994-06-24 1995-06-23 Pulsatile delivery systems of biologically active agents using electro voltage pulsing for controlling membrane permeability Abandoned AU2947795A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26530694A 1994-06-24 1994-06-24
US265306 1994-06-24
PCT/US1995/007951 WO1996000111A1 (en) 1994-06-24 1995-06-23 Pulsatile delivery systems of biologically active agents using electro voltage pulsing for controlling membrane permeability

Publications (1)

Publication Number Publication Date
AU2947795A true AU2947795A (en) 1996-01-19

Family

ID=23009917

Family Applications (1)

Application Number Title Priority Date Filing Date
AU29477/95A Abandoned AU2947795A (en) 1994-06-24 1995-06-23 Pulsatile delivery systems of biologically active agents using electro voltage pulsing for controlling membrane permeability

Country Status (5)

Country Link
EP (1) EP0766579A1 (ja)
JP (1) JPH10511008A (ja)
AU (1) AU2947795A (ja)
CA (1) CA2194010A1 (ja)
WO (1) WO1996000111A1 (ja)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6009345A (en) * 1992-08-17 1999-12-28 Genetronics, Inc. Method and apparatus for a combination of electroporation and iontophoresis for the delivery of drugs and genes
DK1314400T3 (da) * 1996-12-31 2007-10-15 Altea Therapeutics Corp Mikroporering af væv til levering af bioaktive midler
DE69829287T2 (de) 1997-06-30 2006-04-13 Centre National De La Recherche Scientifique (Cnrs) Verbesserung der verabreichung der nukleinsäure in zellen der plurizellulären eukaryotischen organismen und kombination zur durchführung des verfahrens
EP0991426B2 (fr) 1997-06-30 2007-03-28 Institut Gustave Roussy Procede de transfert d'acide nucleique dans le muscle strie
WO1999012606A1 (en) * 1997-09-08 1999-03-18 Becton Dickinson And Company Iontophoretic delivery of buprenorphine
CA2311474C (en) * 1997-11-04 2012-10-02 Genetronics, Inc. Combined electroporation and iontophoresis apparatus for drug and gene delivery
TW368420B (en) * 1997-11-04 1999-09-01 Genetronics Inc Apparatus and method for transdermal molecular delivery by applying sufficient amplitude of electric field to induce migration of molecules through pores in the stratum corneum
WO2003046170A1 (en) * 2001-11-27 2003-06-05 Cellectricon Ab A method for combined parallel agent delivery and electroporation for cell structures and use thereof
US6778853B1 (en) 1997-12-17 2004-08-17 University Of South Florida Electroporation device
US6192270B1 (en) 1998-08-14 2001-02-20 Genetronics, Inc. Apparatus and method for the delivery of drugs and genes into tissue
US6148232A (en) * 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
MXPA01007996A (es) * 1999-02-10 2004-03-26 Gmp Drug Delivery Inc Parches de iontoforesis, electroporacion y combinacion para entrega local de droga..
US7089053B1 (en) 1999-10-14 2006-08-08 Pola Chemical Industries Inc Compositions for drug administration by electroporation
JP4566496B2 (ja) * 1999-12-15 2010-10-20 ユニヴァーシティ オブ サウス フロリダ 電気穿孔素子及び電気穿孔方法
WO2004036202A1 (en) 2002-10-16 2004-04-29 Cellectricon Ab Nanoelectrodes and nanotips for recording transmembrane currents in a plurality of cells
CA2520867A1 (en) * 2003-04-02 2004-10-21 Colin E. Rowlings Pulsatile transdermally administered antigens and adjuvants
US20060036209A1 (en) * 2003-11-13 2006-02-16 Janardhanan Subramony System and method for transdermal delivery
RU2334507C2 (ru) * 2004-03-19 2008-09-27 Макнейл Аб Средство для чрескожного введения никотина
EP2205967B1 (en) 2007-10-17 2013-05-01 Syneron Medical Ltd. Dissolution rate verification

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA929386B (en) * 1991-12-03 1993-06-07 Alza Corp Iontophoretic delivery device and power supply therefor.
JPH0670987A (ja) * 1992-08-28 1994-03-15 Katsuro Tachibana 薬物投与・体液採取ユニット及び装置

Also Published As

Publication number Publication date
CA2194010A1 (en) 1996-01-04
EP0766579A1 (en) 1997-04-09
JPH10511008A (ja) 1998-10-27
WO1996000111A1 (en) 1996-01-04

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