CA2187863A1 - Container for staining of cells and tissues in combination with a roller and a support - Google Patents
Container for staining of cells and tissues in combination with a roller and a supportInfo
- Publication number
- CA2187863A1 CA2187863A1 CA002187863A CA2187863A CA2187863A1 CA 2187863 A1 CA2187863 A1 CA 2187863A1 CA 002187863 A CA002187863 A CA 002187863A CA 2187863 A CA2187863 A CA 2187863A CA 2187863 A1 CA2187863 A1 CA 2187863A1
- Authority
- CA
- Canada
- Prior art keywords
- container
- compartments
- outlets
- compartment
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000010186 staining Methods 0.000 title description 9
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 30
- 238000000034 method Methods 0.000 claims description 7
- 239000000427 antigen Substances 0.000 claims description 6
- 102000036639 antigens Human genes 0.000 claims description 6
- 108091007433 antigens Proteins 0.000 claims description 6
- 102000004169 proteins and genes Human genes 0.000 claims description 6
- 108090000623 proteins and genes Proteins 0.000 claims description 6
- 230000001413 cellular effect Effects 0.000 claims description 5
- 238000000151 deposition Methods 0.000 claims description 4
- 230000009172 bursting Effects 0.000 claims description 3
- 230000008021 deposition Effects 0.000 claims description 2
- 239000006185 dispersion Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 description 14
- 239000000523 sample Substances 0.000 description 8
- 102000004190 Enzymes Human genes 0.000 description 7
- 108090000790 Enzymes Proteins 0.000 description 7
- 229940088598 enzyme Drugs 0.000 description 7
- 239000011521 glass Substances 0.000 description 6
- 239000007788 liquid Substances 0.000 description 5
- 238000010276 construction Methods 0.000 description 3
- 230000033001 locomotion Effects 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 229920003023 plastic Polymers 0.000 description 3
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- 102000003992 Peroxidases Human genes 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000007901 in situ hybridization Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 108040007629 peroxidase activity proteins Proteins 0.000 description 2
- -1 polyethylene Polymers 0.000 description 2
- 102000002260 Alkaline Phosphatase Human genes 0.000 description 1
- 108020004774 Alkaline Phosphatase Proteins 0.000 description 1
- 108090001008 Avidin Proteins 0.000 description 1
- 108020003215 DNA Probes Proteins 0.000 description 1
- 239000003298 DNA probe Substances 0.000 description 1
- 229920000219 Ethylene vinyl alcohol Polymers 0.000 description 1
- 108010015776 Glucose oxidase Proteins 0.000 description 1
- 239000004366 Glucose oxidase Substances 0.000 description 1
- 108010001336 Horseradish Peroxidase Proteins 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 108020004518 RNA Probes Proteins 0.000 description 1
- 239000003391 RNA probe Substances 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 239000003637 basic solution Substances 0.000 description 1
- 102000005936 beta-Galactosidase Human genes 0.000 description 1
- 108010005774 beta-Galactosidase Proteins 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000013581 critical reagent Substances 0.000 description 1
- 230000026058 directional locomotion Effects 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 239000004715 ethylene vinyl alcohol Substances 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 229940116332 glucose oxidase Drugs 0.000 description 1
- 235000019420 glucose oxidase Nutrition 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- RZXDTJIXPSCHCI-UHFFFAOYSA-N hexa-1,5-diene-2,5-diol Chemical compound OC(=C)CCC(O)=C RZXDTJIXPSCHCI-UHFFFAOYSA-N 0.000 description 1
- 238000009396 hybridization Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 239000011140 metalized polyester Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 239000013610 patient sample Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/505—Containers for the purpose of retaining a material to be analysed, e.g. test tubes flexible containers not provided for above
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1002—Reagent dispensers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N2001/317—Apparatus therefor spraying liquids onto surfaces
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Clinical Laboratory Science (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US546795P | 1995-10-16 | 1995-10-16 | |
| US60/005,467 | 1995-10-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2187863A1 true CA2187863A1 (en) | 1997-04-17 |
Family
ID=21716020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002187863A Abandoned CA2187863A1 (en) | 1995-10-16 | 1996-10-15 | Container for staining of cells and tissues in combination with a roller and a support |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5843793A (enExample) |
| EP (1) | EP0768519B1 (enExample) |
| JP (1) | JP3734899B2 (enExample) |
| AT (1) | ATE249035T1 (enExample) |
| CA (1) | CA2187863A1 (enExample) |
| DE (1) | DE69629777T2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH690628A5 (de) * | 1996-03-22 | 2000-11-15 | Intex Pharmazeutische Produkte | Testbesteck, bestehend aus einem Blister, und seine Verwendung. |
| GB9824202D0 (en) | 1998-11-04 | 1998-12-30 | Moore David F | Liquid transfer system |
| EP1158057A1 (en) * | 2000-05-18 | 2001-11-28 | Centre National De La Recherche Scientifique | Compositions and methods applicable to genetic analyses |
| GB0129816D0 (en) * | 2001-12-13 | 2002-01-30 | The Technology Partnership Plc | Testing device for chemical or biochemical analysis |
| US7332348B2 (en) * | 2003-02-28 | 2008-02-19 | Applera Corporation | Sample substrate having a divided sample chamber and method of loading thereof |
| WO2008012550A2 (en) | 2006-07-28 | 2008-01-31 | Diagnostics For The Real World, Ltd. | Device, system and method for processing a sample |
| WO2009024773A1 (en) | 2007-08-17 | 2009-02-26 | Diagnostics For The Real World, Ltd | Device, system and method for processing a sample |
| US20120187021A1 (en) * | 2011-01-25 | 2012-07-26 | Analogic Corporation | Sample carrier and sample carrier processing apparatus |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3654091A (en) * | 1968-05-09 | 1972-04-04 | Aerojet General Co | Incubation chamber |
| US3785771A (en) * | 1969-08-19 | 1974-01-15 | Du Pont | Method and apparatus for analyzing a liquid containing macromolecules that would interfere with the analysis |
| US3770382A (en) * | 1971-07-15 | 1973-11-06 | Du Pont | Automatic clinical analyzer |
| US4040420A (en) * | 1976-04-22 | 1977-08-09 | General Dynamics | Packaging and dispensing kit |
| US4659677A (en) * | 1983-05-26 | 1987-04-21 | Eastman Kodak Company | Method providing liquid mixing outside containers |
| AT379311B (de) * | 1984-03-29 | 1985-12-27 | Immuno Ag | Vorrichtung zur applikation eines gewebeklebstoffes |
| US4978336A (en) * | 1987-09-29 | 1990-12-18 | Hemaedics, Inc. | Biological syringe system |
| US5229297A (en) * | 1989-02-03 | 1993-07-20 | Eastman Kodak Company | Containment cuvette for PCR and method of use |
| US5089233A (en) * | 1989-06-12 | 1992-02-18 | Eastman Kodak Company | Processing apparatus for a chemical reaction pack |
| US5258314A (en) * | 1991-03-18 | 1993-11-02 | Paradigm Biotechnologies Partnership | Microprocessor-based biomedical monitoring apparatus and method |
| US5254479A (en) | 1991-12-19 | 1993-10-19 | Eastman Kodak Company | Methods for preventing air injection into a detection chamber supplied with injected liquid |
| US5290518A (en) * | 1992-08-17 | 1994-03-01 | Eastman Kodak Company | Flexible extraction device with burstable sidewall |
| US5288463A (en) * | 1992-10-23 | 1994-02-22 | Eastman Kodak Company | Positive flow control in an unvented container |
| US5593065A (en) * | 1995-04-10 | 1997-01-14 | Pakmax, Inc. | Metered dual dispenser cap for squeeze containers |
-
1996
- 1996-10-10 US US08/728,586 patent/US5843793A/en not_active Expired - Lifetime
- 1996-10-15 JP JP27256196A patent/JP3734899B2/ja not_active Expired - Fee Related
- 1996-10-15 CA CA002187863A patent/CA2187863A1/en not_active Abandoned
- 1996-10-15 AT AT96307500T patent/ATE249035T1/de not_active IP Right Cessation
- 1996-10-15 EP EP96307500A patent/EP0768519B1/en not_active Expired - Lifetime
- 1996-10-15 DE DE69629777T patent/DE69629777T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69629777T2 (de) | 2004-07-15 |
| EP0768519B1 (en) | 2003-09-03 |
| EP0768519A3 (en) | 1998-06-10 |
| DE69629777D1 (de) | 2003-10-09 |
| EP0768519A2 (en) | 1997-04-16 |
| JPH09133676A (ja) | 1997-05-20 |
| US5843793A (en) | 1998-12-01 |
| ATE249035T1 (de) | 2003-09-15 |
| JP3734899B2 (ja) | 2006-01-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20061010 |