CA2179376A1 - Novel intermediates for the synthesis of l-aspartyl-d-.alpha.-aminoalkanoyl-(s)-n-.alpha.-alkylbenzyl amides useful as artificial sweeteners - Google Patents
Novel intermediates for the synthesis of l-aspartyl-d-.alpha.-aminoalkanoyl-(s)-n-.alpha.-alkylbenzyl amides useful as artificial sweetenersInfo
- Publication number
- CA2179376A1 CA2179376A1 CA002179376A CA2179376A CA2179376A1 CA 2179376 A1 CA2179376 A1 CA 2179376A1 CA 002179376 A CA002179376 A CA 002179376A CA 2179376 A CA2179376 A CA 2179376A CA 2179376 A1 CA2179376 A1 CA 2179376A1
- Authority
- CA
- Canada
- Prior art keywords
- ch2ch3
- co2ch2
- cho
- alpha
- aspartyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Seasonings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17199693A | 1993-12-22 | 1993-12-22 | |
| US08/171,996 | 1993-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2179376A1 true CA2179376A1 (en) | 1995-06-29 |
Family
ID=22625935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002179376A Abandoned CA2179376A1 (en) | 1993-12-22 | 1994-12-22 | Novel intermediates for the synthesis of l-aspartyl-d-.alpha.-aminoalkanoyl-(s)-n-.alpha.-alkylbenzyl amides useful as artificial sweeteners |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0736037A1 (Direct) |
| JP (1) | JPH09507076A (Direct) |
| KR (1) | KR970700201A (Direct) |
| AU (1) | AU1442995A (Direct) |
| CA (1) | CA2179376A1 (Direct) |
| FI (1) | FI962592A0 (Direct) |
| IL (1) | IL111990A0 (Direct) |
| NO (1) | NO962620L (Direct) |
| PE (1) | PE25195A1 (Direct) |
| TW (1) | TW282450B (Direct) |
| WO (1) | WO1995017418A2 (Direct) |
| ZA (1) | ZA9410199B (Direct) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996030381A1 (en) * | 1995-03-28 | 1996-10-03 | Novo Nordisk A/S | Immunosuppressive agents |
| FR2744454B1 (fr) * | 1996-02-07 | 1998-04-24 | Nofre Claude | Acide n-(3,3-dimethylbutyl)-l-aspartyl-d-alpha- aminoalcanoique n-(s)-1-phenyl-1-alcanamide utile comme agent edulcorant |
| US8044173B2 (en) | 2005-09-13 | 2011-10-25 | University Of Reading | Asymmetric synthesis of peptides |
| GB0518667D0 (en) | 2005-09-13 | 2005-10-19 | Univ Reading The | Method |
| US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
| US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4411925A (en) * | 1980-01-21 | 1983-10-25 | Pfizer Inc. | Branched amides of L-aspartyl-d-amino acid dipeptides |
| US4730076A (en) * | 1985-12-18 | 1988-03-08 | Nippon Kayaku Kabushiki Kaisha | Process for producing α-aspartyl-phenylalanine ester |
| AT394854B (de) * | 1986-06-12 | 1992-07-10 | Biochemie Gmbh | Verfahren zur herstellung von n-l-alpha-aspartyl-l-phenylalanin(nieder)alkylestern |
| DE59009485D1 (de) * | 1989-01-26 | 1995-09-14 | Bayer Ag | Optisch aktive (Meth)Acrylsäure-Derivate, ihre Herstellung, ihre Polymerisation zu optisch aktiven Polymeren und deren Verwendung. |
| US5286509A (en) * | 1992-06-22 | 1994-02-15 | The Coca-Cola Company | L-aspartyl-D-α-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as artificial sweeteners |
-
1994
- 1994-12-15 IL IL11199094A patent/IL111990A0/xx unknown
- 1994-12-21 ZA ZA9410199A patent/ZA9410199B/xx unknown
- 1994-12-22 AU AU14429/95A patent/AU1442995A/en not_active Abandoned
- 1994-12-22 KR KR1019960703374A patent/KR970700201A/ko not_active Withdrawn
- 1994-12-22 WO PCT/US1994/014770 patent/WO1995017418A2/en not_active Ceased
- 1994-12-22 FI FI962592A patent/FI962592A0/fi not_active Application Discontinuation
- 1994-12-22 EP EP95906070A patent/EP0736037A1/en not_active Withdrawn
- 1994-12-22 JP JP7517595A patent/JPH09507076A/ja active Pending
- 1994-12-22 CA CA002179376A patent/CA2179376A1/en not_active Abandoned
- 1994-12-22 PE PE1994257675A patent/PE25195A1/es not_active Application Discontinuation
-
1995
- 1995-01-16 TW TW084100341A patent/TW282450B/zh active
-
1996
- 1996-06-20 NO NO962620A patent/NO962620L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1995017418A3 (en) | 1995-10-19 |
| IL111990A0 (en) | 1995-03-15 |
| EP0736037A1 (en) | 1996-10-09 |
| ZA9410199B (en) | 1995-09-04 |
| FI962592L (fi) | 1996-06-20 |
| JPH09507076A (ja) | 1997-07-15 |
| FI962592A7 (fi) | 1996-06-20 |
| WO1995017418A2 (en) | 1995-06-29 |
| PE25195A1 (es) | 1995-09-29 |
| AU1442995A (en) | 1995-07-10 |
| KR970700201A (ko) | 1997-01-08 |
| FI962592A0 (fi) | 1996-06-20 |
| NO962620L (no) | 1996-08-19 |
| TW282450B (Direct) | 1996-08-01 |
| NO962620D0 (no) | 1996-06-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |