CA2175059A1 - Preparation pharmaceutique granulaire - Google Patents

Preparation pharmaceutique granulaire

Info

Publication number
CA2175059A1
CA2175059A1 CA002175059A CA2175059A CA2175059A1 CA 2175059 A1 CA2175059 A1 CA 2175059A1 CA 002175059 A CA002175059 A CA 002175059A CA 2175059 A CA2175059 A CA 2175059A CA 2175059 A1 CA2175059 A1 CA 2175059A1
Authority
CA
Canada
Prior art keywords
ebselen
pharmaceutical preparation
granular pharmaceutical
particle size
average particle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002175059A
Other languages
English (en)
Inventor
Hiroaki Nakagami
Taketoshi Keshikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA002175059A priority Critical patent/CA2175059A1/fr
Publication of CA2175059A1 publication Critical patent/CA2175059A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D293/00—Heterocyclic compounds containing rings having nitrogen and selenium or nitrogen and tellurium, with or without oxygen or sulfur atoms, as the ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C391/00—Compounds containing selenium

Abstract

L'invention concerne une préparation granulaire obtenue en granulant de l'ebsélène (2-phényle-1,2-benzisosélénazol-3(2H)-one) finement pulvérisé avec un polymère hydrophile, et une suspension aqueuse de la préparation. Cette préparation est excellente, car elle peut être administrée par une sonde gastrique. En effet, elle se disperse rapidement et de manière homogène dans l'eau ou dans une solution aqueuse dans laquelle elle est en suspension avant utilisation, et elle reste bien dans cet état. Cela facilite la production d'une solution médicamenteuse contenant cette préparation et son administration par une sonde. En outre, la préparation granulaire et la solution médicamenteuse contenant cette dernière peuvent être administrées sans rester dans la sonde, ce qui permet d'administrer une dose précise. Par ailleurs, il est possible de produire cette préparation sans utiliser d'appareil et de procédé spéciaux, ce qui permet de procéder à une production de masse.
CA002175059A 1993-10-27 1993-10-27 Preparation pharmaceutique granulaire Abandoned CA2175059A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002175059A CA2175059A1 (fr) 1993-10-27 1993-10-27 Preparation pharmaceutique granulaire

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002175059A CA2175059A1 (fr) 1993-10-27 1993-10-27 Preparation pharmaceutique granulaire

Publications (1)

Publication Number Publication Date
CA2175059A1 true CA2175059A1 (fr) 1995-05-04

Family

ID=4158070

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002175059A Abandoned CA2175059A1 (fr) 1993-10-27 1993-10-27 Preparation pharmaceutique granulaire

Country Status (1)

Country Link
CA (1) CA2175059A1 (fr)

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued