CA2166988A1 - Novel dialkoxy-pyridinyl-benzimidazole derivatives - Google Patents
Novel dialkoxy-pyridinyl-benzimidazole derivativesInfo
- Publication number
- CA2166988A1 CA2166988A1 CA002166988A CA2166988A CA2166988A1 CA 2166988 A1 CA2166988 A1 CA 2166988A1 CA 002166988 A CA002166988 A CA 002166988A CA 2166988 A CA2166988 A CA 2166988A CA 2166988 A1 CA2166988 A1 CA 2166988A1
- Authority
- CA
- Canada
- Prior art keywords
- methyl
- pyridinyl
- carbomethoxy
- benzimidazole
- sulfinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| WOPCT/SE94/00511 | 1994-05-27 | ||
| SE9400511 | 1994-05-27 | ||
| PCT/SE1995/000519 WO1995032959A1 (en) | 1994-05-27 | 1995-05-11 | Novel dialkoxy-pyridinyl-benzimidazole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2166988A1 true CA2166988A1 (en) | 1995-12-07 |
Family
ID=20392945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002166988A Abandoned CA2166988A1 (en) | 1994-05-27 | 1995-05-11 | Novel dialkoxy-pyridinyl-benzimidazole derivatives |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0712401A1 (xx) |
| JP (1) | JPH09504557A (xx) |
| CN (1) | CN1128997A (xx) |
| AU (1) | AU2633095A (xx) |
| BR (1) | BR9506235A (xx) |
| CA (1) | CA2166988A1 (xx) |
| CZ (1) | CZ24396A3 (xx) |
| EE (1) | EE9600011A (xx) |
| FI (1) | FI960367A0 (xx) |
| HU (1) | HU9600005D0 (xx) |
| IL (1) | IL113604A0 (xx) |
| IS (1) | IS4321A (xx) |
| MA (1) | MA23563A1 (xx) |
| NO (1) | NO960268L (xx) |
| PL (1) | PL312692A1 (xx) |
| TN (1) | TNSN95062A1 (xx) |
| WO (1) | WO1995032959A1 (xx) |
| ZA (1) | ZA954125B (xx) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9423968D0 (en) * | 1994-11-28 | 1995-01-11 | Astra Ab | Resolution |
| GB9423970D0 (en) * | 1994-11-28 | 1995-01-11 | Astra Ab | Oxidation |
| US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| WO2000028975A2 (en) | 1998-11-18 | 2000-05-25 | Astrazeneca Ab | Improved chemical process and pharmaceutical formulation |
| US8206741B2 (en) | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
| US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| MX2009004475A (es) | 2006-10-27 | 2009-08-12 | Univ Missouri | Composiciones que comprenden agentes acido labiles que inhiben la bomba de protones, por lo menos otro agente farmaceuticamente activo y metodos de uso de las misma. |
| EP2252274A4 (en) | 2008-02-20 | 2011-05-11 | Univ Missouri | COMPOSITION COMPRISING A COMBINATION OF OMEPRAZOLE AND LANSOPRAZOLE, AND A BUFFER AGENT, AND METHODS OF USING THE SAME |
| AU2009290712A1 (en) | 2008-09-09 | 2010-03-18 | Astrazeneca Ab | Method for delivering a pharmaceutical composition to patient in need thereof |
| CA2764963C (en) | 2009-06-25 | 2016-11-01 | Astrazeneca Ab | Method for treating a patient at risk for developing an nsaid-associated ulcer |
| UA115139C2 (uk) | 2011-12-28 | 2017-09-25 | Поузен Інк. | Спосіб доставки фармацевтичної композиції, яка містить омепразол й ацетилсаліцилову кислоту, пацієнту |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE184602T1 (de) * | 1990-06-20 | 1999-10-15 | Astra Ab | Dialkoxypyridinylbenzimidazolderivate, verfahren zur herstellung und ihre pharmazeutische verwendung |
| DE4035455A1 (de) * | 1990-11-08 | 1992-05-14 | Byk Gulden Lomberg Chem Fab | Enantiomerentrennung |
-
1994
- 1994-05-29 TN TNTNSN95062A patent/TNSN95062A1/fr unknown
-
1995
- 1995-05-03 IL IL11360495A patent/IL113604A0/xx unknown
- 1995-05-11 EP EP95921187A patent/EP0712401A1/en not_active Withdrawn
- 1995-05-11 CN CN95190482A patent/CN1128997A/zh active Pending
- 1995-05-11 PL PL95312692A patent/PL312692A1/xx unknown
- 1995-05-11 CA CA002166988A patent/CA2166988A1/en not_active Abandoned
- 1995-05-11 BR BR9506235A patent/BR9506235A/pt not_active Application Discontinuation
- 1995-05-11 WO PCT/SE1995/000519 patent/WO1995032959A1/en not_active Application Discontinuation
- 1995-05-11 JP JP8500730A patent/JPH09504557A/ja active Pending
- 1995-05-11 EE EE9600011A patent/EE9600011A/xx unknown
- 1995-05-11 AU AU26330/95A patent/AU2633095A/en not_active Abandoned
- 1995-05-11 HU HU9600005A patent/HU9600005D0/hu unknown
- 1995-05-11 CZ CZ96243A patent/CZ24396A3/cs unknown
- 1995-05-19 ZA ZA954125A patent/ZA954125B/xx unknown
- 1995-05-26 MA MA23901A patent/MA23563A1/fr unknown
-
1996
- 1996-01-17 IS IS4321A patent/IS4321A/is unknown
- 1996-01-23 NO NO960268A patent/NO960268L/no unknown
- 1996-01-26 FI FI960367A patent/FI960367A0/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CZ24396A3 (en) | 1996-06-12 |
| TNSN95062A1 (fr) | 1996-02-06 |
| MA23563A1 (fr) | 1995-12-31 |
| NO960268D0 (no) | 1996-01-23 |
| ZA954125B (en) | 1995-11-27 |
| CN1128997A (zh) | 1996-08-14 |
| FI960367A (fi) | 1996-01-26 |
| JPH09504557A (ja) | 1997-05-06 |
| NO960268L (no) | 1996-01-23 |
| FI960367A0 (fi) | 1996-01-26 |
| HU9600005D0 (en) | 1996-03-28 |
| BR9506235A (pt) | 1997-08-12 |
| EE9600011A (et) | 1996-04-15 |
| IL113604A0 (en) | 1995-08-31 |
| WO1995032959A1 (en) | 1995-12-07 |
| IS4321A (is) | 1996-01-17 |
| EP0712401A1 (en) | 1996-05-22 |
| PL312692A1 (en) | 1996-05-13 |
| AU2633095A (en) | 1995-12-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1020460B1 (en) | The sodium salt of the (-)-enantiomer of omeprazole | |
| US6875872B1 (en) | Compounds | |
| CA2166988A1 (en) | Novel dialkoxy-pyridinyl-benzimidazole derivatives | |
| WO1995032957A1 (en) | Novel ethoxycarbonyloxymethyl derivatives of substituted benzimidazoles | |
| CA2166987A1 (en) | Novel substituted benzimidazoles | |
| AU676337C (en) | Optically pure salts of pyridinylmethyl sulfinyl-IH- benzimidazole compounds | |
| SK5896A3 (en) | Substituted benzimideazoles |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |